The molecular mechanisms of chronic exercise to improve the developmental disorders
Project/Area Number |
21500642
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Sports science
|
Research Institution | Nakamura Gakuen College |
Principal Investigator |
NAKANO Hiroshi 中村学園大学, 教育学部, 准教授 (60301678)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
Keywords | スポーツ生理学 / 発達障害 / 甲状腺ホルモン / モリス水迷路 / 学習・記憶 / 運動 / ランニング / BDNF / TrkB / 十字迷路 / ロータロッド / ラット / 行動 |
Research Abstract |
Propylthiouracil(PTU)-induced thyroid hormone insufficiency during development has caused developmental disorder, e. g. less anxiety, motor impairment, and learning and memory impairment. On the other hand, running exercise training has enhanced spatial learning in alterations of brain BDNF level in subjects exposed to hypothyroid in the neonatal period.
|
Report
(4 results)
Research Products
(11 results)