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The molecular mechanisms of chronic exercise to improve the developmental disorders

Research Project

Project/Area Number 21500642
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionNakamura Gakuen College

Principal Investigator

NAKANO Hiroshi  中村学園大学, 教育学部, 准教授 (60301678)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsスポーツ生理学 / 発達障害 / 甲状腺ホルモン / モリス水迷路 / 学習・記憶 / 運動 / ランニング / BDNF / TrkB / 十字迷路 / ロータロッド / ラット / 行動
Research Abstract

Propylthiouracil(PTU)-induced thyroid hormone insufficiency during development has caused developmental disorder, e. g. less anxiety, motor impairment, and learning and memory impairment. On the other hand, running exercise training has enhanced spatial learning in alterations of brain BDNF level in subjects exposed to hypothyroid in the neonatal period.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (11 results)

All 2011 2010 2009 Other

All Presentation (10 results) Remarks (1 results)

  • [Presentation] 空間記憶保持に及ぼす走運動の影響2011

    • Author(s)
      中野裕史
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 空間記憶保持に及ぼす走運動の影響2011

    • Author(s)
      中野裕史
    • Organizer
      第66回日本体力医学会大会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 乳児期の甲状腺ホルモン撹乱による行動特性の変化と脳由来神経栄養因子の関係2010

    • Author(s)
      中野裕史
    • Organizer
      第65回日本体力医学会大会
    • Place of Presentation
      千葉
    • Year and Date
      2010-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 乳児期の甲状腺ホルモン撹乱による行動特性の変化と脳由来神経栄養因子の関係2010

    • Author(s)
      中野裕史
    • Organizer
      第65回日本体力医学会大会
    • Place of Presentation
      千葉商科大学
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 甲状腺ホルモン撹乱による発達障害モデルラット2010

    • Author(s)
      中野裕史
    • Organizer
      第3回脳・神経・内分泌系から運動の意義を考える会
    • Place of Presentation
      和洋女子大学
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 恐怖刺激を伴う運動は発達障害の症状を悪化させる2010

    • Author(s)
      中野裕史
    • Organizer
      第18回日本運動生理学会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-08-01
    • Related Report
      2011 Final Research Report
  • [Presentation] 恐怖刺激を伴う運動は発達障害の症状を悪化させる2010

    • Author(s)
      中野裕史
    • Organizer
      第18回日本運動生理学会大会
    • Place of Presentation
      鹿児島大学
    • Year and Date
      2010-08-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] 幼児・児童の健康問題を考える―環境変化と脳機能の視点より―2009

    • Author(s)
      中野裕史
    • Organizer
      九州体育・スポーツ学会第58回大会
    • Place of Presentation
      崇城大学(熊本)
    • Year and Date
      2009-09-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effects of exercise training on spatial learning and serum brain-derived neurotrophic factor in PTU-exposed rat2009

    • Author(s)
      Nakano H
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences
    • Place of Presentation
      京都
    • Year and Date
      2009-07-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Effects of exercise training on spatial learning and serum brain-derived neurotrophic factor in PTU-exposed rat2009

    • Author(s)
      中野裕史
    • Organizer
      第36回国際生理学会世界大会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2009-07-29
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.nakamura-u.ac.jp/

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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