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New viewpoint for prevention of life style-related diseases-verification of thrifty phenotype hypothesis

Research Project

Project/Area Number 21500684
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionKyoto University

Principal Investigator

TSUDA Kinsuke  京都大学, 大学院・人間・環境学研究科, 教授 (10180001)

Co-Investigator(Kenkyū-buntansha) FUKUSIMA Mituo  岡山県立大学, 保健福祉部, 教授 (60271392)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords生活習慣病 / 生下時体重 / 倹約表現型仮説 / DOH_aD(Developmental Origin ofHealth and Disease) / DOHaD / BMI / 血糖値 / 糖尿病 / 肥満 / 食育
Research Abstract

To clarify the relationships between birth weight and life style related diseases, we examined medical examination. The subjects are two groups. We got birth weights by their maternity health record books. In 243 Japanese healthy high school girls the association of low birth weight could be detected to be significant with such risks of metabolic syndrome as SBP, DBP, TG, insulin level and insulin resistance indicating the importance of follow-up study and food education program for the prevention of MS in the later life. In middle aged group medical examination the relationship between the birth weight and present BMI shows U curve. The ratio of fasting plasma glucose levels over 100mg/dl is high in low birth weight group. These data show that low birth weight is high risk for life style-related diseases in later life.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (22 results)

All 2012 2011 2010 2009

All Journal Article (8 results) (of which Peer Reviewed: 4 results) Presentation (7 results) Book (7 results)

  • [Journal Article] Low Birth Weight as Cardio metabolic Risk in Japanese High School Girls2012

    • Author(s)
      Mori M, Mori H, Yamori Y, K Tsuda
    • Journal Title

      J American College 0f Nutrition

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Low Birth Weight as Cardiometabolic Risk in Japanese High School Girls2012

    • Author(s)
      Mori M.H.Mori, Y.Yamori, K.Tsuda
    • Journal Title

      J.American College of Nutrition

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 糖尿病治療の新時代-2010年代の展望2010

    • Author(s)
      津田謹輔
    • Journal Title

      内科

      Volume: 105 Pages: 49-51

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 糖尿病の食事療法の実際と注意点2010

    • Author(s)
      津田謹輔
    • Journal Title

      日本医師会雑誌

      Volume: 139 Pages: 146-149

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] Association of estrogen-arufa gene polymorphism with cardiac autonomic nervous activity in healthy young Japanese males2010

    • Author(s)
      Matsunaga T, K. Tsudaet
    • Journal Title

      Clin Chem Acta

      Volume: 411 Pages: 505-509

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association of estrogen-arufa gene polymorphism with cardiac autonomic Nervous activity in healthy young Japanese males2010

    • Author(s)
      T.Matsunaga, et al.
    • Journal Title

      Clin Chem Acta

      Volume: 411 Pages: 505-509

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 栄養不足と生活習慣病2009

    • Author(s)
      津田謹輔
    • Journal Title

      日本体質医学会雑誌

      Volume: 71 Pages: 84-88

    • Related Report
      2011 Final Research Report
  • [Journal Article] 栄養丕足と生活と習慣病2009

    • Author(s)
      津田謹輔
    • Journal Title

      日本体質医学会雑誌 71

      Pages: 84-88

    • Related Report
      2009 Annual Research Report
  • [Presentation] 生下時体重と成人後のBMI、血糖値の関係についての検討2012

    • Author(s)
      福島光夫、津田謹輔他7名
    • Organizer
      第66回日本栄養・食糧学会大会東北大学
    • Place of Presentation
      東北大学
    • Year and Date
      2012-05-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活習慣病についての新しい視点~栄養と遺伝の接点~2011

    • Author(s)
      津田謹輔
    • Organizer
      第10回日本栄養改善学会近畿支部学術総会
    • Place of Presentation
      奈良女子大学
    • Year and Date
      2011-12-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 生活習慣病についての新しい視点~栄養と遺伝の接点~2011

    • Author(s)
      津田謹輔
    • Organizer
      第10回日本栄養改善学会近畿支部学術総会
    • Place of Presentation
      奈良女子大学(招待講演)
    • Year and Date
      2011-12-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 食事療法の新しい展開2011

    • Author(s)
      津田謹輔
    • Organizer
      第45回糖尿病学の進歩(招待講演)
    • Place of Presentation
      福岡
    • Year and Date
      2011-02-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 食事療法の新しい展開2011

    • Author(s)
      津田謹輔
    • Organizer
      第45回糖尿病学の進歩
    • Place of Presentation
      福岡
    • Year and Date
      2011-02-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 糖尿病食事療法の温故知新2010

    • Author(s)
      津田謹輔
    • Organizer
      日本病態栄養学会
    • Place of Presentation
      京都
    • Year and Date
      2010-01-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 糖尿病食事療法の温故知新2010

    • Author(s)
      津田謹輔
    • Organizer
      病態栄養学会
    • Place of Presentation
      国立京都会館
    • Year and Date
      2010-01-10
    • Related Report
      2009 Annual Research Report
  • [Book] 糖尿病の療養指導2011

    • Author(s)
      日本糖尿病学会編
    • Publisher
      診断と治療社
    • Related Report
      2011 Final Research Report
  • [Book] スマートな糖尿病診断と治療の進め方2011

    • Author(s)
      荒木栄一
    • Publisher
      中山書店
    • Related Report
      2011 Final Research Report
  • [Book] すべてがわかる糖尿病2011

    • Author(s)
      門脇孝、真田弘美
    • Publisher
      照林社
    • Related Report
      2011 Final Research Report
  • [Book] 糖尿病研修ノート2010

    • Author(s)
      永井良三、門脇孝
    • Publisher
      診断と治療社
    • Related Report
      2011 Final Research Report
  • [Book] 新しい診断と治療のABC糖尿病2010

    • Author(s)
      花房俊昭
    • Publisher
      最新医学社
    • Related Report
      2011 Final Research Report
  • [Book] 新しい診断と治療のABC糖尿病 改訂第2版2010

    • Author(s)
      花房俊昭編集
    • Total Pages
      286
    • Publisher
      最新医学社
    • Related Report
      2010 Annual Research Report
  • [Book] 糖尿病治療の新しい展開2009

    • Author(s)
      津田謹輔(共蓍)
    • Total Pages
      127
    • Publisher
      文光堂
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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