| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
Hypertension is recognized as an important factor to cause cardiovascular diseases, such as myocardial infraction and stroke. Oxidative stress is known to participate for development of the hypertension. We revealed the effect of exercise training for the oxidative damage on the tissues of hypertensive model rat caused by hypertension, in order to clarify the bases of exercise therapy for hypertension. We have developed a new marker for oxidative stress, which is 6-nitrotryptophan, and established the method to apply this marker for the analysis of exercise effect on the hypertensive model rats.
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