| Project/Area Number |
21500781
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Nayoro City University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Tatsuro 名寄市立大学, 保健福祉学部, 講師 (90379389)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 大腸内発酵 / 窒素供給 / 腸内細菌叢 / 食事導入期 / 離乳 / 酪酸 / 短鎖脂肪酸 / 大豆タンパク質 / 肥満 / 窒素 / タンパク質 / 水素 / 腸内細菌 |
|---|
| Research Abstract |
To determine whether protein affects formation of the colonic environment during the weaning period, we examined the change in colonic microbiota and fermentation in weaning rats fed different proteins. Colonic microbiota, colonized by soy protein isolate during the weaning period, were stable and produced high amounts of butyrate. The same phenomenon was also observed in obese mice, suggesting that unique colonic microbiota were formed by the administration of soy protein isolate during the weaning period. In addition, the administration of soy protein isolate may be involved in the suppression of fat accumulation due to the unique microbiota. Taken together, we found that the administration of appropriate protein during the weaning period established a healthy colonic environment.
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