Screening of food components for the prevention of alcoholic liver diseases and their application
Project/Area Number |
21500783
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Eating habits, studies on eating habits
|
Research Institution | Osaka City University |
Principal Investigator |
YUASA Akiko 大阪市立大学, 大学院・生活科学研究科, 准教授 (90295709)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
|
Keywords | 健康と食生活 / 生活習慣病 / 食品成分 / アルコール性肝疾患 / 肝細胞 / 肝星細胞 / 栄養学 / 食品 |
Research Abstract |
We studied the protection against ethanol-induced liver injury by various food components. The goal of this study is to propose a utilization of them into our dietary habits for the prevention of the disease. We examined the protective effect of various food components by using in vitro cell culture models for hepatitis and for liver cirrhosis and an in vivo animal model for liver disease, which were developed by us. Then we got the following results. We found that Ecklonia cava extract, extract from Tamatsukuri-kuromon Shirouri, sesame lignin and Mate tea extract have the protective effects for ethanol-induced liver injury on our in vitro and in vivo models and suggested that the ingestion of these components is useful for our healthy life.
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Report
(4 results)
Research Products
(33 results)