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The effects of food intake restriction that is not in coordination with circadian rhythms on reproductive functions in young women

Research Project

Project/Area Number 21500813
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionAshiya College

Principal Investigator

FUJIWARA Tomoko  芦屋学園短期大学, その他, 教授 (60310744)

Co-Investigator(Kenkyū-buntansha) NAKATA Rieko  奈良女子大学, 生活環境学部, 講師 (90198119)
FUJIWARA Hiroshi  京都大学, 医学研究科, 准教授 (30252456)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords女子大学生 / 婦人科疾患 / 食習慣 / ラット実験モデル / 食育プログラム
Research Abstract

On the basis of the novel concept that diet habits in young women during the adolescence influence the subsequent quality of life(QOL) of women of the reproductive ages, in this study, we conducted the questionnaire survey concerning the daily dietary habits, the self-recognition of body stature, dieting practice and general conditions from female college students of 18-20 years old in order to elicit significant dietary habit factors that affect reproductive functions. In addition, we examined dietary habits more precisely by food nutritional analysis. Furthermore, using young adult female rat experiments, we investigated the relationship between the timing of food intake restriction and estrous cycle to know the effects of dietary habits on the reproductive functions.
The questionnaire survey confirmed that breakfast skipping is one of the important factors that adversely affect reproductive functions in young women and showed the possibility that nocturnal life style is associated with breakfast skipping. Food nutritional analysis showed that students with breakfast skipping did not supplement themselves with food energy, suggesting that breakfast is one of the reasons for lack of calories take in. In addition, animal experiments showed that greater impairment of the estrus cycle in young female rats that were starved during the day, i. e., the daytime(non-active phase) than those that were starved at night(active phase).
From these results, we proposed a new hypothesis that the timing of food consumption in daily life is an important issue that affects reproductive function in the young. These findings will contribute to establishing a new dietary education program to reduce the adverse effects of diets on reproductive functions in young women.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (31 results)

All 2012 2011 2010 2009

All Journal Article (11 results) (of which Peer Reviewed: 4 results) Presentation (18 results) Book (2 results)

  • [Journal Article] 食事調査から見る若年女性における栄養素摂取の状況2011

    • Author(s)
      藤原智子
    • Journal Title

      研究紀要(芦屋女子短期大学)

      Volume: 37 Pages: 13-32

    • NAID

      40018829122

    • Related Report
      2011 Final Research Report
  • [Journal Article] 介護食のQOL向上を目指して-介護食士3級取得講座実施報告-2011

    • Author(s)
      藤原智子、蔭山猛、小久江次郎、松原美紗
    • Journal Title

      芦屋学園短期大学研究紀要

      Volume: 38 Pages: 47-51

    • NAID

      40019214512

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Skipping breakfast is associated with reproductive dysfunction in post-adolescent female college students2010

    • Author(s)
      Fujiwara T, Nakata R
    • Journal Title

      Appetite

      Volume: 55 Pages: 714-717

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 食事と生体リズムと生殖機能2010

    • Author(s)
      藤原智子
    • Journal Title

      研究紀要(芦屋女子短期大学)

      Volume: 36 Pages: 1-19

    • NAID

      40017417063

    • Related Report
      2011 Final Research Report
  • [Journal Article] Skipping breakfast is associated with reproductive dysfunction in post-adolescent female college students.2010

    • Author(s)
      Eujiwara T, Nakata R.
    • Journal Title

      Appetite

      Volume: 55 Pages: 714-717

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食事と生体リズムと生殖機能2010

    • Author(s)
      藤原智子
    • Journal Title

      芦屋女子短期大学研究紀要

      Volume: 36 Pages: 1-19

    • NAID

      40017417063

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 食事調査から見る若年女性における栄養素摂取の状況2010

    • Author(s)
      藤原智子
    • Journal Title

      芦屋女子短期大学研究紀要

      Volume: 37 Pages: 13-32

    • NAID

      40018829122

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Skipping breakfast adversely affects menstrual disorders in young college students2009

    • Author(s)
      Fujiwara T, Sato N, Awaji H, Sakamoto H, Nakata R
    • Journal Title

      Int J Food Sci Nutr

      Volume: 60 Pages: 23-31

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 女子大学生の生殖機能に及ぼす朝食欠食の影響に関する継続的実態調査2009

    • Author(s)
      藤原智子
    • Journal Title

      研究紀要(芦屋女子短期大学)

      Volume: 34 Pages: 15-23

    • NAID

      40016998477

    • Related Report
      2011 Final Research Report
  • [Journal Article] Skipping breakfast adversely affects menstrual disorders in young college students.2009

    • Author(s)
      Fujiwara T, et al.
    • Journal Title

      International Journal of Food Sciences and Nutrition Epub ahead of print

      Pages: 1-9

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 女子大学生の生殖機能に及ぼす朝食欠食の影響に関する継続的実態調査2009

    • Author(s)
      藤原智子
    • Journal Title

      芦屋女子短期大学研究紀要 34

      Pages: 15-23

    • NAID

      40016998477

    • Related Report
      2009 Annual Research Report
  • [Presentation] 朝食欠食は若年女性の生殖機能に悪影響を及ぼす2011

    • Author(s)
      藤原智子
    • Organizer
      第26回日本女性医学学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-11-12
    • Related Report
      2011 Final Research Report
  • [Presentation] Novel local regulatorymechanisms for human embryo attachment and invasion2011

    • Author(s)
      Fujiwara H
    • Organizer
      The 4^<th> International Conference of Repeated Implantation Failure
    • Place of Presentation
      広州中国
    • Year and Date
      2011-11-12
    • Related Report
      2011 Final Research Report
  • [Presentation] 若年女性の生殖機能に対する朝食欠食の抑制作用の実験的検証2011

    • Author(s)
      藤原智子
    • Organizer
      第26回日本女性医学学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Improvement of implantation rates using autologous peripheral blood mononuclear cells2011

    • Author(s)
      Fujiwara H
    • Organizer
      16th World Congress on In Vitro Fertilization
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2011-09-12
    • Related Report
      2011 Final Research Report
  • [Presentation] Skipping breakfast adversely affects reproductive function in post-adolescent female college students2011

    • Author(s)
      Fujiwara T, Nakata R
    • Organizer
      XI Asian Congress of Nutrition
    • Place of Presentation
      Singapore
    • Year and Date
      2011-07-13
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 食事リズムが若年女性の生殖機能に及ぼす影響について2011

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第63回大会
    • Place of Presentation
      千葉
    • Year and Date
      2011-05-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 食事リズムが若年女性の生殖機能に及ぼす影響について2011

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第63回大会
    • Place of Presentation
      和洋女子大学
    • Year and Date
      2011-05-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Circulating immune cells can promote embryo implantation2011

    • Author(s)
      Fujiwara H
    • Organizer
      31th Annual Meeting of The American Society for Reproductive Immunology
    • Place of Presentation
      Salt Lake City, U. S. A
    • Year and Date
      2011-05-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 若年女性の生殖機能に対する朝食欠食の抑制作用の実験的検証2011

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本栄養・食糧学会第65会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 若年女性の生殖機能に対する朝食欠食の抑制作用の実験的検証2011

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本栄養・食糧学会第65会大会
    • Place of Presentation
      お茶の水女子大学
    • Year and Date
      2011-05-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] 思春期直後の性成熟完成期にあたる女性を対象とした食事調査結果について2010

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本調理科学会平成22年度大会
    • Place of Presentation
      福岡
    • Year and Date
      2010-08-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 思春期直後の性成熟完成期にあたる女性を対象とした食事調査結果について2010

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本調理科学会平成22年度大会
    • Place of Presentation
      中村学園大学
    • Year and Date
      2010-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] 食生活習慣が若年女性の生殖機能に及ぼす影響について2010

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第62回大会
    • Place of Presentation
      広島
    • Year and Date
      2010-05-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 食生活習慣が若年女性の生殖機能に及ぼす影響について2010

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第62回大会
    • Place of Presentation
      広島大学
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 朝食の欠食が若年女性の生殖機能に及ぼす影響について2009

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第61回大会
    • Place of Presentation
      武庫川女子大学
    • Year and Date
      2009-08-31
    • Related Report
      2009 Annual Research Report
  • [Presentation] 朝食の欠食が若年女性の生殖機能に及ぼす影響について2009

    • Author(s)
      藤原智子、中田理恵子
    • Organizer
      日本家政学会第61回大会
    • Place of Presentation
      兵庫
    • Year and Date
      2009-08-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 朝食の欠食が思春期後の女子大学生の生殖機能に悪影響を及ぼす可能性について2009

    • Author(s)
      藤原智子
    • Organizer
      日本調理科学会平成21年度大会
    • Place of Presentation
      同志社女子大学
    • Year and Date
      2009-08-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 朝食の欠食が思春期後の女子大学生の生殖機能に悪影響を及ぼす可能性について2009

    • Author(s)
      藤原智子
    • Organizer
      日本調理科学会平成21年度大会
    • Place of Presentation
      京都
    • Year and Date
      2009-08-28
    • Related Report
      2011 Final Research Report
  • [Book] Skipping breakfast is associated with constipation in post-adolescent female college students in Japan. Chapter 4 ; In Constipation-Causes, Diagnosis and Treatment2012

    • Author(s)
      Fujiwara T
    • Publisher
      InTech Open Access Publisher
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] Immune regulation of human embryo implantation by circulating blood cells2011

    • Author(s)
      Fujiwara H, Sato Y, Ideta A, Aoyagi Y, Araki Y and Imakawa K
    • Publisher
      InTech Open Access Publisher
    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2020-06-02  

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