Construction of New Theoretical Modeling to Understand and Control Single Quantum Dot Intermittent Blinking
Project/Area Number |
21510123
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Nanomaterials/Nanobioscience
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Research Institution | Hokkaido University |
Principal Investigator |
LI Chun-biu 北海道大学, 電子科学研究所, 准教授 (90397795)
|
Co-Investigator(Renkei-kenkyūsha) |
KOMATSUZAKI Tamiki 北海道大学, 電子科学研究所, 教授 (30270549)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 1分子計測(SMD) / 量子ドット / ナノバイオ / 物性理論 / 光物性 |
Research Abstract |
To elucidate the mechanisms of intermittent blinking kinetics, we developed a series of novel data-driven time series analysis and modeling techniques to extract the underlying kinetic scheme directly from single molecule (SM) quantum dot (QD) fluorescence experiments. These include the development and application of the change-point analysis that allows us to correctly extract the on and off intensity dwell-time statistics, and the development of a novel kinetic scheme (KS) construction methodology which unveils the most unbiased KS capturing the full statistical information from time series. The developed methods have demonstrated their high reliability and applicability not only in SM QD experiments, but also in a wide range of other SM measurements, such as in the SM enzymatic turnover experiments and the SM F1_ATPase rotation assessments.
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Report
(4 results)
Research Products
(68 results)
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[Presentation] 階層構造をつくる多変数確率過程の数理2011
Author(s)
宮川尚紀, 寺本央, Chun-Biu Li, 小松崎民樹
Organizer
分子科学討論会(札幌)2011
Place of Presentation
札幌コンベンションセンター(札幌市)(一般、ポスター)
Year and Date
2011-09-21
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