Direct observation of the proton/hydrogen-atom transfer reaction under the restricted initial configuration

• Project/Area Number: 21550016
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Physical chemistry
• Research Institution: Kobe University
• Principal Investigator: ISHIKAWA Haruki 神戸大学, 大学院・理学研究科, 准教授 (80261551)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: プロトン移動反応 / 水素結合クラスター / 赤外分光 / 共鳴2光子イオン化 / 蛍光励起スペクトル / フェノール-ペプチドクラスター / フェノールーペプチドクラスター

Research Abstract

We have planned to investigate the proton-transfer reaction along the peptides. Using neutral hydrogen-bonded cluster as a precursor, the initial configuration of the reaction can be restricted. In the present study, phenol-amino acid clusters are used as the precursor, where phenol acts as the proton donor. We have recorded resonance-enhanced two-photon ionization and infrared spectra and calculated the optimized structures and their energies. At the present, there are some problems in the cluster production method. Thus, we are planning to continue this study.

Research Products

• [Journal Article] Infrared Spectroscopy of Jet-Cooled Tautomeric Dimer of 7-Azaindole : A Model System for the Ground-State Double Proton Transfer Reaction (2010)
  • Author(s): H. Ishikawa, H. Yabuguchi, Y. Yamada, A. Fujihara, K. Fuke
  • Journal Title: J. Phys. Chem Volume: A, 114巻 Pages: 3199-3206
  • Peer Reviewed
• [Journal Article] Infrared Spectroscopy of Jet-Cooled Tautomeric Dimer of 7-Azaindole : A Model System for the Ground-State Double Proton Transfer Reaction (2010)
  • Author(s): H.Ishikawa, H.Yabuguchi, Y.Yamada, A.Fujihara, K.Fuke
  • Journal Title: Journal of Physical Chemistry A 114 Pages: 3199-3206
  • Peer Reviewed
• [Presentation] Infrared spectroscopy of phenol-amino acid clusters (2010)
  • Author(s): NAKANO TAKUMI, ISHIKAWA HA RUKI, 他2名
  • Organizer: Pacifichem 2010
  • Place of Presentation: ホノルル
  • Year and Date: 2010-12-17
• [Presentation] Infrared spectroscopy of phenol-amino acid clusters (2010)
  • Author(s): T.Nakano, H.Yabuguchi, K.Fuke, H.Ishikawa
  • Organizer: 2010環太平洋国際化学会議
  • Place of Presentation: ホノルル(アメリカ合衆国)
  • Year and Date: 2010-12-17
• [Presentation] 水素結合クラスターを利用したペプチド内プロトン移動反応の研究 (2010)
  • Author(s): 薮口紘基・石川春樹, 他2名
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 東大阪
  • Year and Date: 2010-03-28
• [Presentation] 水素結合クラスターを用いたペプチド内プロトン移動反応の研究 (2010)
  • Author(s): 薮口紘基・石川春樹・藤原亮正・冨宅喜代一
  • Organizer: 日本化学会第90春季年会(2010)
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] 水素結合クラスターを利用したペプチド内プロトン移動反応の研究 (2009)
  • Author(s): 薮口紘基・石川春樹, 他2名
  • Organizer: 第3回分子科学討論会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-09-21
• [Presentation] 水素結合クラスターを利用したペプチド内プロトン移動反応の研究 (2009)
  • Author(s): 薮口紘基・石川春樹・藤原亮正・冨宅喜代一
  • Organizer: 第3回分子科学討論会
  • Place of Presentation: 名古屋大学(愛知県)
  • Year and Date: 2009-09-21