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Study on Amplitude Modulated Multiplexed Flow Analysis and Its Improvement to Analysis of Practicality

Research Project

Project/Area Number 21550083
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Analytical chemistry
Research InstitutionThe University of Tokushima

Principal Investigator

TANAKA Hideji  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (40207121)

Co-Investigator(Kenkyū-buntansha) TAKEUCHI Masaki  徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 (10457319)
Research Collaborator MIMA Takuto  徳島大学, 大学院・薬科学教育部・博士前期課程, 大学院生
KUROKAWA Yohei  徳島大学, 大学院・薬科学教育部・博士前期課程, 大学院生
UEMURA Takeshi  徳島大学, 大学院・薬科学教育部・博士前期課程, 大学院生
OGUSU Takeshi  徳島大学, 薬学部薬学科, 学生
INUI Koji  徳島大学, 薬学部薬学科, 学生
YOSHIDA Haruka  徳島大学, 薬学部薬学科, 学生
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywordsフロー分析 / 自動分析 / 振幅変調 / 多重化 / フーリエ変換 / 同時分析 / 空気分節 / 周波数解析
Research Abstract

Amplitude modulated multiplexed flow analysis is a new concept for simultaneous analysis of multiple samples based on frequency analysis. In this study, we have 1) improved the throughput of the measurement by the optimization of the system and analytical conditions, 2) proposed a concept for the simultaneous determination of multiple analytes in a sample, and 3) limited the axial dispersion through the segmentation of the liquid stream with of air-bubbles for sensitivity enhancement. The developed system has successfully been applied to the determinations of phosphate ions, chloride ions, ferrous & ferric ions, nitrite & nitrate ions, and so on, in environmental water samples.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (43 results)

All 2012 2011 2010 2009 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (33 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Simultaneous Determination of Nitrite and Nitrate Ions by Air-Segmented Amplitude-Modulated Multiplexed Flow Analysis2012

    • Author(s)
      Haruka Yoshida, Koji Inui, Masaki Takeuchi, Hideji Tanaka
    • Journal Title

      Analytical Sciences

      Volume: 28 Issue: 5 Pages: 523-525

    • DOI

      10.2116/analsci.28.523

    • NAID

      10030757752

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simultaneous Determination of Nitrite and Nitrate Ions by Air-Segmented Amplitude Modulated Multiplexed Flow Analysis2012

    • Author(s)
      Yoshida, H
    • Journal Title

      Analytical Science

      Volume: 28(5)(in press)

    • NAID

      10030757752

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Air-Segmented Amplitude-Modulated Multiplexed Flow Analysis2011

    • Author(s)
      Koji Inui, Takeshi Uemura, Takeshi Ogusu, Masaki Takeuchi, Hideji Tanaka
    • Journal Title

      Analytical Sciences

      Volume: 27 Issue: 3 Pages: 305

    • DOI

      10.2116/analsci.27.305

    • NAID

      10027906376

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Air-Segmented Amplitude-Modulated multiplexed Flow Analysis2011

    • Author(s)
      Koji Inui, et al
    • Journal Title

      Analytical Sciences

      Volume: 27(3) Pages: 305-308

    • NAID

      10027906376

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spectrophotometric Determination of Trace Phosphate Ions by Amplitude-Modulated Flow Analysis Coupled with Malachite Green Method2010

    • Author(s)
      Takeshi Uemura, Takeshi Ogusu, Masaki Takeuchi, Hideji Tanaka
    • Journal Title

      Analytical Sciences

      Volume: 26 Issue: 7 Pages: 797-801

    • DOI

      10.2116/analsci.26.797

    • NAID

      10026784550

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analytical Parameters for Amplitude-Modulated Multiplexed Flow Analysis2010

    • Author(s)
      Yohei Kurokawa, Masaki Takeuchi, Hideji Tanaka
    • Journal Title

      Analytical Sciences

      Volume: 26 Issue: 7 Pages: 791-796

    • DOI

      10.2116/analsci.26.791

    • NAID

      10026784530

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Investigation on Analytical Parameters for Amplitude Modulated Multiplexed Flow Analysis2010

    • Author(s)
      Yohei Kurokawa, et al.
    • Journal Title

      Analytical Sciences

      Volume: 26(6) Pages: 791-796

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spectrophotometric Determination of Trace Phosphate Ion by Amplitude Modulated Flow Analysis Coupled with Malachite Green Method2010

    • Author(s)
      Takeshi Uemura, et al.
    • Journal Title

      Analytical Sciences

      Volume: 26(6) Pages: 797-801

    • NAID

      10026784550

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Simultaneous Determination of Multiple Analytes by Amplitude Modulated Multiplexed Flow Analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      第49回フローインジェクション分析研究懇談会
    • Place of Presentation
      愛知工業大学(豊田市)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Air Segmented-Amplitude Modulated Multiplexed Flow Analysis without Deaeration2011

    • Author(s)
      Takeshi Ogusu
    • Organizer
      第49回フローインジェクション分析研究懇談会
    • Place of Presentation
      愛知工業大学(豊田市)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Air Segmented-Amplitude Modulated Multiplexed Flow Analysis without Deaeration2011

    • Author(s)
      Takeshi Ogusu
    • Organizer
      第49回フローインジェクション分析研究懇談会
    • Place of Presentation
      愛知工業大学(名古屋市)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] Simultaneous Determination of Multiple Analytes by Amplitude Modulated Multiplexed Flow Analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      第49回フローインジェクション分析研究懇談会
    • Place of Presentation
      愛知工業大学(名古屋市)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 気節-非相分離/振幅変調フロー分析法による高感度化2011

    • Author(s)
      大楠剛司
    • Organizer
      第60回日本分析化学会年会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 気節-非相分離/振幅変調フロー分析法による高感度化2011

    • Author(s)
      大楠剛司
    • Organizer
      日本分析化学会第60年会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] Air-segmented amplitude modulated multiplexed flow analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      The 14th Asian Chemical Congress 2011
    • Place of Presentation
      The Queen Sirikit National Convention Center(Bangkok, Thailand)
    • Year and Date
      2011-09-06
    • Related Report
      2011 Final Research Report
  • [Presentation] Air-segmented amplitude modulated multiplexed flow analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      The 14th Asian Chemical Congress 2011
    • Place of Presentation
      The Queen Sirikit National Convention Center (Bangkok, Thailand)(招待講演)
    • Year and Date
      2011-09-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] Air Segmented Amplitude Modulated Multiplexed Flow Analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011
    • Place of Presentation
      Kyoto International Conference Center(Kyoto, Japan)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Amplitude Modulated Multiplexed Flow Analysis for Simultaneous Determination2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011
    • Place of Presentation
      Kyoto International Conference Center(Kyoto, Japan)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Amplitude Modulated Multiplexed Flow Analysis for Simultaneous Determination2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011
    • Place of Presentation
      Kyoto International Conference Center(京都市)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Air Segmented Amplitude Modulated Multiplexed Flow Analysis2011

    • Author(s)
      Hideji Tanaka
    • Organizer
      IUPAC International Congress on Analytical Sciences 2011
    • Place of Presentation
      Kyoto International Conference Center(京都市)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Amplitude modulated multiplexed flow analysis for simultaneous determination of chloride ions2010

    • Author(s)
      Yohei Kurokawa
    • Organizer
      The Second Decennial Meeting Between The University of Tokushima and Soul National University on Pharmaceutical Sciences
    • Place of Presentation
      Awaji Yumebutai International Conference Center(Awaji, Japan)
    • Year and Date
      2010-12-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Amplitude modulated multiplexed flow analysis for simultaneous determination of chloride ions2010

    • Author(s)
      Yohei Kurokawa
    • Organizer
      The Secod Decennial Meeting Between The University of Tokuhsima and Soul National University on Pharmaceutical Sciences
    • Place of Presentation
      Awaji Yumebutai International Conference Center(Awaji, Japan)
    • Year and Date
      2010-12-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Principle and application of amplitude modulated multiplexed flow analysis2010

    • Author(s)
      Hideji Tanaka
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2010
    • Place of Presentation
      Hawaii Convention Center(Honolulu, Hawaii, USA)
    • Year and Date
      2010-12-19
    • Related Report
      2011 Final Research Report
  • [Presentation] Principle and application of amplitude modulated multiplexed flow analysis2010

    • Author(s)
      Hideji Tanaka
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2010
    • Place of Presentation
      Hawaii Convention Center(Honolulu, Hawaii, USA)(招待講演)
    • Year and Date
      2010-12-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Air-segmented amplitude modulated flow analysis2010

    • Author(s)
      Hideji Tanaka
    • Organizer
      The International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii Convention Center(Honolulu, Hawaii, USA)
    • Year and Date
      2010-12-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Air-segmented amplitude modulated flow analysis2010

    • Author(s)
      Hideji Tanaka
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2010
    • Place of Presentation
      Hawaii Convention Center(Honolulu, Hawaii, USA)
    • Year and Date
      2010-12-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 振幅変調フロー分析法による微量リン酸イオンの定量2010

    • Author(s)
      上村剛史
    • Organizer
      第20回無機リン化学討論会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2010-10-07
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 振幅変調多重化フロー分析法の原理と応用.塩化物イオン,鉄イオンの定量2010

    • Author(s)
      黒河洋平
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2010-09-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 流量変化に基づく分析法:フローレイショメトリーと振幅変調フロー分析法2010

    • Author(s)
      田中秀治
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2010-09-15
    • Related Report
      2011 Final Research Report
  • [Presentation] 流量変化に基づく分析法;フローレイショメトリーと振幅変調フロー分析法2010

    • Author(s)
      田中秀治
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学(仙台市)(招待講演)
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 振幅変調多重化フロー分析法の原理と応用.塩化物イオン, 鉄イオンの定量2010

    • Author(s)
      黒河洋平
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 気節導入による振幅変調フロー分析法の高感度化2010

    • Author(s)
      田中秀治
    • Organizer
      第71回分析化学討論会
    • Place of Presentation
      島根大学(松江市)
    • Year and Date
      2010-05-15
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 振幅変調/ロックイン検出フロー分析法によるリン酸イオンの定量2009

    • Author(s)
      田中秀治
    • Organizer
      第48回フローインジェクション分析講演会
    • Place of Presentation
      大阪府立大学(堺市)
    • Year and Date
      2009-11-27
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 振幅変調フロー分析法2009

    • Author(s)
      上村剛史
    • Organizer
      マラカイトグリーン法による微量リン酸イオンの定量
    • Place of Presentation
      東京医科歯科大学(東京都文京区)
    • Year and Date
      2009-10-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 振幅変調フロー分析法/マラカイトグリーン法による微量リン酸イオンの定量2009

    • Author(s)
      上村剛史
    • Organizer
      第19回無機リン化学討論会
    • Place of Presentation
      東京医科歯科大学(東京都文京区)
    • Year and Date
      2009-10-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] 振幅変調多重化フロー分析法の測定効率向上のための検討2009

    • Author(s)
      黒河洋平
    • Organizer
      日本分析化学会第58年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2009-09-24
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] 振幅変調多重化フロー分析法によるFe(II)およびFe(III)の同時定量2009

    • Author(s)
      美馬卓人
    • Organizer
      日本分析化学会第58年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2009-09-24
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] Determination of Phosphate Ion by Amplitude Modulated Flow Analysis with Lock-in Detection2009

    • Author(s)
      Hideji Tanaka
    • Organizer
      Flow Analysis XI
    • Place of Presentation
      Pollentia Club Resort(Mallorca, Spain
    • Year and Date
      2009-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Amplitude Modulated Multiplexed Flow Analysis. Application to Simultaneous Determination of Ferrous and Ferric Ions2009

    • Author(s)
      Hideji Tanaka
    • Organizer
      Flow Analysis XI
    • Place of Presentation
      Pollentia Club Resort(Mallorca, Spain)
    • Year and Date
      2009-09-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Amplitude Modulated Multiplexed Flow Analysis. Application to Simultaneous Determination of Ferrous and Ferric Ions2009

    • Author(s)
      Hideji Tanaka
    • Organizer
      Flow Analysis XI
    • Place of Presentation
      Mallorca, Spain
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Determination of Phosphate Ion by Amplitude Modulated Flow Analysis with Lock-in Detection2009

    • Author(s)
      Hideji Tanaka
    • Organizer
      Flow Analysis XI
    • Place of Presentation
      Mallorca, Spain
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Book] 薬学分析科学の最前線2009

    • Author(s)
      田中秀治, 竹内政樹
    • Publisher
      じほう出版
    • Related Report
      2011 Final Research Report
  • [Remarks] 徳島大学広報,「最先端研究探訪」

    • URL

      http://www.tokushima-u.ac.jp/docs/2011102600010/files/saisentan145.pdf

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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