An Efficient Access to Chiral Compounds via Asymmetric Hydrogenation of Polar Functional Groups
Project/Area Number |
21550096
|
Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Synthetic chemistry
|
Research Institution | Kyushu University |
Principal Investigator |
ITO Masato 九州大学, 先導物質化学研究所, 准教授 (20293037)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 触媒設計・反応 / 不斉合成反応 / 合成化学 / 触媒・科学プロセス / 水素 / 省エネルギー / 触媒・化学プロセス |
Research Abstract |
Novel molecular catalysts have been developed for the straightforward hydrogenation of a range of carboxylic acid derivatives under mild conditions. Modular design of chiral molecular catalysts could provide direct access to stereochemically well-defined moleculres, which might otherwise have required a detour to reach. Another important finding in this study is that the coexistence of inorganic base has led to dramatic improvement in their catalytic activity.
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Report
(4 results)
Research Products
(64 results)
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[Presentation] Ryo Watari, Takashi Ootsuka, Akira Shiibashi, Akio Himizu, Masato Ito, Hydrogenation of Esters and Carboxamides Promoted by Bifunctional Cp^* Ru Catalysts2011
Author(s)
Ryo Watari, Takashi Ootsuka, Akira Shiibashi, Akio Himizu, Masato Ito, Takao Ikariya
Organizer
16^<th> IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis
Place of Presentation
Shanghai, China
Year and Date
2011-07-24
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