| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
Ciguatera fish poisoning(CFP) is an ichthyosarcotoxism caused by the consumption of tropical and subtropical coral fish contaminated with toxic polyether compounds, ciguatoxins(CTXs) and maitotoxin(MTX). Garrec et al. have reported that the extracts of some southern medicinal plants, traditionally used to treat CFP, to prevent in vitro neurotoxicity produced by CTX or brevetoxin(BTX). Here, we studied new CFP antitoxic compounds isolated from verious southern medicinal plants by using in vitro neurotoxicity assay.
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