Fabrication of anodized titanium artificial bone induced osteoblast cells
| Project/Area Number |
21550193
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Inorganic industrial materials
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| Research Institution | Kinki University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HAMANISHI Chiaki 近畿大学, 医学部, 准教授 (00164921)
MATSUZAKI Kohji 近畿大学, 医学部, 助教 (60510964)
NOMA Naoki 近畿大学, 理工学部, 講師 (70208388)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | ハイブリッド材料 / ハイドロキシアパタイト / アノード酸化 / パターニング / アノード酸化チタン / 細胞誘導 / 骨芽細胞 / 人工骨 / 生体親和性 |
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| Research Abstract |
Micrometer-scale patterning-TiO_2 films derived by sol-gel method were formed on a titanium plate using by photo-irradiation patterning method. The patterned TiO_2 gel film onto titanium was then anodized at constant current density with DC or pulsed-current density by anodic oxidation in an HAp-containing alkaline bath under spark discharge, to follow preparing various pore shapes on patterned-TiO_2 film. Moreover, reversed patterning-film was also prepared by the combination of photosensitizing and anodizing method except etching process. The bioactivity, which was investigated by cell culture examination, was drastically improved for HAp-loaded titania film in comparison with anodized titanium film without HAp.
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Report
(4 results)
Research Products
(83 results)
