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Investigations of the mechanical properties of the spinal cord at high strain rates for computer simulation model of the spinal cord injury

Research Project

Project/Area Number 21560107
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Materials/Mechanics of materials
Research InstitutionTokuyama College of Technology

Principal Investigator

SAKURAMOTO Itsuo  徳山工業高等専門学校, 機械電気工学科, 教授 (70225853)

Research Collaborator ICHIHARA Kazuhiko  日本運動器バイオメカニクス研究所, 医師
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords生体力学 / 生体材料 / 生物・生体工学 / 医療・福祉
Research Abstract

In the present study, we made the original high speed tensile equipment(Maximum crosshead speed 1, 000mm/s), and investigated the mechanical properties of the pia mater(postero-lateral sulcus, posterior median septum, dentate ligament) andspinal parenchyma(gray matter, white matter), which are the important parts to analyze the stress distribution within the spinal cord. The results exhibit the characteristic nonlinear and viscoelastic stress-strain response, in which the stiffness of the material increases with strain and strain rate. Furthermore, the gray matter is stiffer but fails at a lower mechanical strain than the white matter at high strain rates.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2011 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (10 results)

  • [Journal Article] 脊髄の生体力学2011

    • Author(s)
      市原和彦,大木順司,陳献,櫻本逸男, 他2名
    • Journal Title

      脊椎脊髄ジャーナル

      Volume: Vol.24, No.12 Pages: 1101-1107

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脊髄の生体力学2011

    • Author(s)
      市原和彦
    • Journal Title

      脊椎脊髄ジャーナル

      Volume: 24(No.12) Pages: 1101-1107

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Mechanical properties of the pia mater in the spinal cord at high strain rates for computersimulation model of the spinal cord injury2011

    • Author(s)
      Itsuo Sakuramoto, Kazuhiko Ichihara, Junji Ohgi, Xian Chen, 他2名
    • Organizer
      The 41rd Annual Meeting of the Societyfor Neuroscience
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Final Research Report
  • [Presentation] The finite element analysis for onset mechanisms of spinal cord injury and cervical spondylotic myelopathy2011

    • Author(s)
      Kazuhiko Ichihara, Itsuo Sakuramoto, Junji Ohgi, Xian Chen, 他2名
    • Organizer
      The 41rd Annual Meeting of the Societyfor Neuroscience
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Mechanical properties of the pia mater in the spinal cord at high strain rates for computer simulation model of the spinal cord injury2011

    • Author(s)
      櫻本逸男
    • Organizer
      The 41rd Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Walter E.Washington Convention Center (Washington, USA)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] The finite element analysis for the onset mechanisms of spinal cord injury and cervical spondylotic myelopathy2011

    • Author(s)
      市原和彦
    • Organizer
      The 41rd Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Walter E.Washington Convention Center (Washington, USA)
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 圧迫性頸髄障害の発症メカニズム解明2011

    • Author(s)
      市原和彦,森田英隆,宮崎誠也,大木順司,櫻本逸男, 他4名
    • Organizer
      第26回日本脊髄外科学会
    • Place of Presentation
      沼津市民文化センター
    • Year and Date
      2011-06-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 圧迫性頚髄障害の発症メカニズム解明2011

    • Author(s)
      市原和彦
    • Organizer
      第26回日本脊髄外科学会
    • Place of Presentation
      沼津市民文化センター(沼津市)
    • Year and Date
      2011-06-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脊髄圧迫形態慢性による脊髄障害の変化2010

    • Author(s)
      市原和彦、森田英隆、宮崎誠也、大木順司、櫻本逸男, 他
    • Organizer
      第37回日本臨床バイオメカニクス学会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脊髄根糸、くも膜の力学特性-脊髄有限要素解析導入に向けて2010

    • Author(s)
      市原和彦、宮崎誠也、森田英隆、大木順司、櫻本逸男, 他
    • Organizer
      第37回日本臨床バイオメカニクス学会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脊髄質量を導入した急性脊髄圧迫有限要素解析2010

    • Author(s)
      市原和彦、森田英隆、大木順司、櫻本逸男, 他
    • Organizer
      第39回日本脊椎脊髄病学会
    • Place of Presentation
      高知県立県民文化ホール(高知市)
    • Year and Date
      2010-04-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新鮮豚脊髄神経根-くも膜-軟膜-硬膜結合部の引張り試験-鞭打ち傷害は外傷性低髄圧症候群を起こしえるか?-2009

    • Author(s)
      市原和彦、西裕美子、大木順司、櫻本逸男
    • Organizer
      第36回日本臨床バイオメカニクス学会
    • Place of Presentation
      ひめぎんホール(松山市)
    • Year and Date
      2009-10-17
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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