Assessment of bone biology using 3-D structured bone substitute manufactured by rapid prototyping technology
| Project/Area Number |
21560720
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
ADACHI Taiji 京都大学, 再生医科学研究所, 教授 (40243323)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 生体内吸収材料 / 三次元構造 / 構造解析 / 経時的変化 / 熱溶融積層法 |
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| Research Abstract |
3-D structured bone substitute was manufactured by rapid prototyping technology. Optimal 3-D structure of biomaterial for both osteoconduction and osteoinduction was assessed using animal model. The results of this study revealed that 1200-micron size pore was suitable for osteoconduction and 500-micron size pore was suitable for osteoinduction. And submicron-size surface structure was also important for bone ingrowth.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Osteoinduction of porous Ti implants with channel structure fabricated by selective laser melting2011
Author(s)
Fukuda A, Takemoto M, Saito T, Fujibayashi S, Neo M, Pattanayak DK, Matsushita T, Sasaki K, Nishida N, Kokubo T, Nakamura T.
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Journal Title
Acta Biomater
Volume: 7
Issue: 5
Pages: 2327-36
DOI
Related Report
Peer Reviewed
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