| Project/Area Number |
21560722
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Osaka University |
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Principal Investigator |
FUJITANI Wataru 大阪大学, 大学院・工学研究科, 技術専門員 (90379149)
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| Co-Investigator(Kenkyū-buntansha) |
NAKANO Takayoshi 大阪大学, 大学院・工学研究科, 教授 (30243182)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKANO Takayoshi 大阪大学, 大学院・工学研究科, 教授 (30243182)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | バイオマテリアル / 下顎骨 / 咀嚼障害モデル / 微小領域XRD / 骨質評価 / 生体アパタイト / c軸配向性 / X線回折 / in vivo応力 / アパタイト配向性 / 咀嚼 / 咀嚼障害 / 骨微細構浩 / 骨微細構造 |
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| Research Abstract |
Mandible, which is formed through intramembranous ossification process, has a well-organized micro-structure comprising preferentially-aligned collagen(Col.)/ biological apatite(BAp) and has a role to bear complicated mechanical stress mainly from biting. The present study is aiming at clarifying the correlation between the preferential alignment of Col./ BAp and mechanical properties of bone by using a microbeam XRD, pQCT and some specific animal models : controlled biting stress and dental extraction, bone metabolism, nutrient disturbance and primary osteoporosis. The present study will provid a direction for designing novel dental implant from a viewpoint of bone microstructure and function.
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