Analysis of change in mandible bone microstructure induced by masticatory malfunction from a viewpoint of crystallography
| Project/Area Number |
21560722
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Osaka University |
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Principal Investigator |
FUJITANI Wataru 大阪大学, 大学院・工学研究科, 技術専門員 (90379149)
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| Co-Investigator(Kenkyū-buntansha) |
NAKANO Takayoshi 大阪大学, 大学院・工学研究科, 教授 (30243182)
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| Co-Investigator(Renkei-kenkyūsha) |
NAKANO Takayoshi 大阪大学, 大学院・工学研究科, 教授 (30243182)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | バイオマテリアル / 下顎骨 / 咀嚼障害モデル / 微小領域XRD / 骨質評価 / 生体アパタイト / c軸配向性 / X線回折 / in vivo応力 / アパタイト配向性 / 咀嚼 / 咀嚼障害 / 骨微細構浩 / 骨微細構造 |
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| Research Abstract |
Mandible, which is formed through intramembranous ossification process, has a well-organized micro-structure comprising preferentially-aligned collagen(Col.)/ biological apatite(BAp) and has a role to bear complicated mechanical stress mainly from biting. The present study is aiming at clarifying the correlation between the preferential alignment of Col./ BAp and mechanical properties of bone by using a microbeam XRD, pQCT and some specific animal models : controlled biting stress and dental extraction, bone metabolism, nutrient disturbance and primary osteoporosis. The present study will provid a direction for designing novel dental implant from a viewpoint of bone microstructure and function.
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Report
(4 results)
Research Products
(29 results)
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[Journal Article] Synthesis of HydroXyapatite Contining Manganese and Its Evaluation of Biocompatibility2010
Author(s)
Wataru FUJITANI, Yoshinosuke HAMADA, Naomasa KAWAGUCHI, Seiji MORI, Kiyoshi DAITO, Ayako UCHINAKA, Takuya MATSUMOTO, Yoshihisa KOJIMA, Michiharu DAITO, Takayoshi NAKANO, and Nariaki MATSUURA
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Journal Title
Nano Biomedicine
Volume: 2(1)
Pages: 37-46
NAID
Related Report
Peer Reviewed
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[Journal Article] Synthesis of Hydroxyapatite Containing Manganese and Its Evaluation of Biocompatibility2010
Author(s)
W.FUJITANI, Y.HAMADA, N.KAWA GUCHI, S.MORI, K.DAIT'O, A.UCHINAKA, T.MATSUMOTO, Y.KOJIMA, M.DAITO, T.NAKANO, N.MATS UURA
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Journal Title
Nano Biomedicine
Volume: Vol.2, No.1
Pages: 37-46
Related Report
Peer Reviewed
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