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Identification and molecular population genetics analysis of speciation genes in Drosophila

Research Project

Project/Area Number 21570001
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Genetics/Genome dynamics
Research InstitutionUniversity of Tsukuba

Principal Investigator

SAWAMURA Kyoichi  筑波大学, 生命環境系, 講師 (90247205)

Co-Investigator(Kenkyū-buntansha) TAKANO Toshiyuki  国立遺伝学研究所, 集団遺伝学研究部門, 准教授 (90202150)
MATSUNO Kenji  東京理科大学, 基礎工学部, 教授 (60318227)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsショウジョウバエ / 種分化 / 生殖的隔離 / 雑種致死 / 雑種不妊 / ヌクレオポリン / 遺伝的不和合 / 核孔複合タンパク
Research Abstract

Previously we succeeded to make an interspecific introgression line in which a part of the genomes of Drosophila melanogaster is replaced by the homologous genes from Drosophila simulans. Introgression homozygotes are sterile both in females and males and the introgression results in recessive lethality when crossed to D. simulans. Thus, the introgression provides an opportunity to genetically analyze reproductive isolation. In the present research, we indicated that Nucleoporin 160 is responsible for the hybrid female sterility and inviability.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (30 results)

All 2012 2011 2010 2009 Other

All Journal Article (8 results) (of which Peer Reviewed: 6 results) Presentation (21 results) Remarks (1 results)

  • [Journal Article] Genetic dissection of Nucleoporin 160(Nup160)2012

    • Author(s)
      K. Maehara, T. Murata, N. Aoyama, K. Matsuno, K. Sawamura
    • Journal Title

      a gene involved in multiple phenotypes of reproductive isolation in Drosophila. Genes and Genetic Systems

      Volume: Vol.87 (印刷中)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chromatin evolution and molecular drive in speciation2012

    • Author(s)
      K. Sawamura
    • Journal Title

      International Journal of Evolutionary Biology

      Volume: Vol.2012

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chromatin evolution and molecular drive in speciation2012

    • Author(s)
      K.Sawamura
    • Journal Title

      International Journal of Evolutionary Biology

      Volume: 2012 Pages: 1-9

    • DOI

      10.1155/2012/301894

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic dissection of Nucleoporin 160(Nup160), a gene involved in multiple phenotypes of reproductive isolation in Drosophila2012

    • Author(s)
      K.Maehara, T.Murata, N.Aoyama, K.Matsuno, K.Sawamura
    • Journal Title

      Genes and Genetic Systems

      Volume: 87(印刷中)

    • NAID

      10030616563

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 種分化の分子生物学-最近の研究から見えてきたこと2011

    • Author(s)
      澤村京一, 前原一慶, 村田孝順
    • Volume
      65巻3号
    • Pages
      2-4
    • NAID

      40018834791

    • Related Report
      2011 Final Research Report
  • [Journal Article] 種分化の分子生物学-最近の研究から見えてきたこと2011

    • Author(s)
      澤村京一、前原一慶、村田孝順
    • Journal Title

      遺伝

      Volume: 65 Pages: 2-4

    • NAID

      40018834791

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Introgression of Drosophila simulans Nuclear Pore Protein 160 in Drosophila melanogaster alone does not cause inviability but does cause female sterility2010

    • Author(s)
      K. Sawamura, K. Maehara, S. Mashino, T. Kagesawa, M. Kajiwara, K. Matsuno, A. Takahashi, T. Takano-Shimizu
    • Journal Title

      Genetics

      Volume: Vol.186 Pages: 669-676

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Introgression of Drosophila simulans Nuclear Pore Protain 160 in Drosophila melanogaster alone does not cause inviability but dces cause female sterility.2010

    • Author(s)
      K.Sawamura, 他7名
    • Journal Title

      Genetics

      Volume: VOL.186 Pages: 669-676

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Genetics of hybrid inviability and sterility between Drosophila melanogaster and Drosophila simulans2012

    • Author(s)
      K. Sawamura
    • Organizer
      Okazaki Biology Conference
    • Place of Presentation
      Okazaki
    • Year and Date
      2012-03-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Genetics of hybrid inviability and sterility between Drosophila melanogaster and Drosophila simulans2012

    • Author(s)
      K.Sawamura
    • Organizer
      Okazaki Biology Conference
    • Place of Presentation
      岡崎(招待講演)
    • Year and Date
      2012-03-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] モデル生物「ショウジョウバエ」を利用した種分化の研究2011

    • Author(s)
      澤村京一
    • Organizer
      日本遺伝学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] モデル生物「ショウジョウバエ」を利用した種分化の研究2011

    • Author(s)
      澤村京一
    • Organizer
      日本遺伝学会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular drive and epigenetics in speciation2011

    • Author(s)
      K. Sawamura
    • Organizer
      Society for Molecular Biology and Evolution
    • Place of Presentation
      Kyoto
    • Year and Date
      2011-07-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Molecular drive and epigenetics in speciation2011

    • Author(s)
      K.Sawamura
    • Organizer
      Society for Molecular Biology and Evolution
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-07-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Drosophila as a model organism for the speciation study : genetic mechanisms of reproductive isolation2011

    • Author(s)
      K. Sawamura
    • Organizer
      International Interdisciplinary Scientific Research Conference
    • Place of Presentation
      Santo Domingo (Dominican Republic)
    • Year and Date
      2011-06-11
    • Related Report
      2011 Final Research Report
  • [Presentation] Drosophila as a model organism for the speciation study : genetic mechanisms of reproductive isolation2011

    • Author(s)
      K.Sawamura
    • Organizer
      International Interdisciplinary Scientific research Conference
    • Place of Presentation
      サントドミンゴ
    • Year and Date
      2011-06-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Genetics of hybrid inviability and sterility between D. melanogaster and D. simulans2011

    • Author(s)
      K. Sawamura
    • Organizer
      Asia-Pacific Drosophila Research Conference
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2011-05-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Genetics of hybrid inviability and sterility between D.melanogaster and D.simulans2011

    • Author(s)
      K.Sawamura
    • Organizer
      Asia-Pacific Drosophila Research Conference
    • Place of Presentation
      台北
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] 核膜孔複合体タンパク遺伝子(Nup160)によるショウジョウバエの雑種致死および不妊2010

    • Author(s)
      前原一慶, 増野昭太郎, 影沢達夫, 梶原三有希, 松野健治, 高橋文, 高野敏行, 澤村京一
    • Organizer
      北海道大学低温科学研究所共同研究集会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report
  • [Presentation] キイロショウジョウバエとオナジショウジョウバエを用いた交配後隔離の遺伝学2010

    • Author(s)
      澤村京一
    • Organizer
      日本遺伝学会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] キイロショウジョウバエとオナジショウジョウバエを用いた交配後隔離の遺伝学2010

    • Author(s)
      澤村京一
    • Organizer
      日本遺伝学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Introgression of Drosophila simulans Nup160 (nuclear pore protein 160) in Drosophila melanogaster alone does not cause inviability but does cause female sterility2010

    • Author(s)
      K. Sawamura, K. Maehara, S. Mashino, T. Kagesawa, M. Kajiwara, K. Matsuno, A. Takahashi, T. Takano-Shimizu
    • Organizer
      International Bio Resource Symposium Drosophila
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-03-18
    • Related Report
      2011 Final Research Report
  • [Presentation] Introgression of D.simulans Nup160 in D.melanogaster alone does not cause inviability but does cause female sterility2010

    • Author(s)
      澤村京一, et al.
    • Organizer
      International BioResource Symposium"Drosophila"
    • Place of Presentation
      比叡山(滋賀)
    • Year and Date
      2010-03-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Nuclear pore protein 160 (Nup160) causes hybrid female sterility and hybrid inviability2009

    • Author(s)
      K. Sawamura, S. Mashino, K. Maehara
    • Organizer
      European Drosophila Research Conference
    • Place of Presentation
      Nice (France)
    • Year and Date
      2009-11-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Nuclear pore protein 160(Nup 160)causes hybrid female sterility and hybrid inviability2009

    • Author(s)
      澤村京一, et al.
    • Organizer
      European Drosophila Research Conference
    • Place of Presentation
      ニース(フランス)
    • Year and Date
      2009-11-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 核膜孔複合タンパク遺伝子(Nup160)はショウジョウバエの雑種雌不妊および雑種致死を引き起こす2009

    • Author(s)
      澤村京一, 前原一慶, 増野昭太郎
    • Organizer
      日本遺伝学会
    • Place of Presentation
      松本
    • Year and Date
      2009-09-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 核膜孔複合タンパク遺伝子(Nup 160)はショウジョウバエの雑種不妊および雑種致死を引き起こす2009

    • Author(s)
      澤村京一, 他
    • Organizer
      日本遺伝学会
    • Place of Presentation
      松本(長野)
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Nucleoporin causes not only hybrid inviability but also female sterility2009

    • Author(s)
      澤村京一, et al.
    • Organizer
      Japanese Drosophila Research Conference
    • Place of Presentation
      掛川(静岡)
    • Year and Date
      2009-07-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Nucleoporin causes not only hybrid inviability but also female sterility2009

    • Author(s)
      K. Sawamura, K. Maehara, S. Mashino, T. Murata
    • Organizer
      Japanese Drosophila Research Conference
    • Place of Presentation
      Kakegawa
    • Year and Date
      2009-07-06
    • Related Report
      2011 Final Research Report
  • [Remarks] International Journal of Evolutionary BiologyにLead Guest Editorとして、特集号Mechanisms of Speciationを組んだ

    • URL

      http://www.hindawi.com/journals/ijeb/si/568376/

    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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