Osmoregulation in elephant fish : introduction of a new model animal for cartilaginous fish research
| Project/Area Number |
21570061
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphology/Structure
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| Research Institution | The University of Tokyo |
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Principal Investigator |
HYODO Susumu 東京大学, 大気海洋研究所, 准教授 (40222244)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 軟骨魚類 / 尿素 / ゾウギンザメ / 腎臓 / 初期発生 / ホルモン受容体 / 体液調節 / 腎機能 / 卵黄嚢上皮 / バソトシン受容体 / 尿素サイクル / 環境適応 / 脳下垂体神経葉ホルモン / 進化 / 輸送体分子 / 個体発生 |
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| Research Abstract |
The aim of this study is to investigate adaptive, reproductive and developmental physiologies of the cartilaginous fish by using elephant fish as a model organism, for which the public genome database is available. We have proposed a urea reabsorption model in the renal nephron by mapping of various transporting proteins for urea, water and ions. In the present study, we also found contribution of the yolk-sac membrane to body fluid regulation in the early developmental stages, and a novel neurohypophysial hormone receptor that is likely to be involved in the maintenance of homeostasis.
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] The fifth neurohypophysial hormone receptor(V4R) is structurally related to the V2-type receptor but functionally similar to V1-and V3-type receptors2012
Author(s)
Yamaguchi, Y., Kaiya, H., Konno, N., Iwata, E., Miyazato, M., Uchiyama, M., Bell, J. D., Toop, T., Donald, J. A., Brenner, S., Venkatesh, B., Hyodo, S.
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Journal Title
Gen. Comp. Endocrinol
Volume: (in press)
Related Report
Peer Reviewed
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[Journal Article] Hepatic and extrahepatic distribution of ornithine urea cycle enzymes in holocephalan elephant fish2012
Author(s)
Takagi, W., Kajimura, M., Bell, J. D., Toop, T., Donald, J. A., Hyodo, S.
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Journal Title
Comp. Biochem. Physiol. B
Volume: 161
Issue: 4
Pages: 331-340
DOI
Related Report
Peer Reviewed
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[Journal Article] A new method to calibrate attachment angles of data loggers in swimming sharks. Eurasip J. Advance in Signal2010
Author(s)
Kawatsu, S., Sato, K., Watanabe, Y., Hyodo, S., Breves, J. P., Fox, B. K., Grau, E. G., Miyazaki, N.
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Journal Title
Processing
Volume: Article ID 732586
Issue: 1
Pages: 732586-732586
DOI
Related Report
Peer Reviewed
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[Journal Article] Rhesus glycoprotein p2(Rhp2) is a novel member of the Rh family of ammonia transporters highly expressed in shark kidney2010
Author(s)
Nakada, T., Westhoff, C. M., Yamaguchi, Y., Hyodo, S., Li, X., Muro, T., Kato, A., Nakamura, N., Hirose, S.
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Journal Title
J. Biol. Chem
Volume: 285
Issue: 4
Pages: 2653-2664
DOI
Related Report
Peer Reviewed
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[Journal Article] Multiple urea transporter proteins in the kidney of holocephalan elephant fish. Comp2009
Author(s)
Kakumura, K., Watanabe, S., Bell, J. D., Donald, J. A., Toop, T., Kaneko, T., Hyodo, S.
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Journal Title
Biochem. Physiol. B
Volume: 154
Pages: 239-247
Related Report
Peer Reviewed
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[Journal Article] African lungfish possess an arginine vasotocin receptor homologous to the tetrapod V2-type receptor2009
Author(s)
Konno, N., Hyodo, S., Yamaguchi, Y., Kaiya, H., Miyazato, M., Matsuda, K., Uchiyama, M.
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Journal Title
J. Exp. Biol
Volume: 212
Issue: 14
Pages: 2183-2193
DOI
Related Report
Peer Reviewed
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