| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
Sphingosine 1-phosphate (S1P) is a lipid mediator which was secreted from vascular endothelial cells by SPNS2. SPNS2 homologues, SPNS1 and SPNS3, were localized at intracellular compartment and not function as a S1P exporter from the cells. We also develop a novel S1P analogue which functions as a light induced cross-linking to SPNS2. This compound would be useful for identification of erythrocyte S1P transportr(s).
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