A Study on the multiplicity and hierarchical control of the mechanism for learning and memory
| Project/Area Number |
21570161
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biophysics
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| Research Institution | University of Toyama |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 脳・神経系の情報処理 / 学習 / 記憶 / 階層性 / 代償性 / 瞬目反射条件付け / 小脳 / 海馬 / NMDA受容体 |
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| Research Abstract |
We investigated the roles of cerebellum and the higher nervous systems in a motor learning task, the classical eyeblink conditioning, in which the basic neural circuit has been elucidated in rabbits. We found that the acquisition and retention of the memory in this task depend on the ipsilateral cerebellum in rats, similarly in rabbits. We also examined the cerebellar dependency in DBA/2 mice, which have an abnormal higher nervous system. DBA/2 mice showed a similar dependency on the ipsilateral cerebellum, which was different from the results reported in C57BL/6 mice.
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Report
(4 results)
Research Products
(17 results)
