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Regulation of ferritin oligomerization and transport in cytoplasm

Research Project

Project/Area Number 21570175
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics
Research InstitutionFukuoka University

Principal Investigator

NAKAGAWA Hiroyuki  福岡大学, 理学部, 准教授 (80274562)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords運動 / 輸送 / ferritin / transport / iron
Research Abstract

Ferritin, an iron storage molecule in cytoplasm, has been shown to transport as oligomer on microtubule, but it has been still unclear motor molecules responsible for that movement. Thus we explored motor molecules binding to ferritin oligomer in cytoplasm prepared from mammalian culture cells. As a result, we found that kinesin, a motor molecule moving along microtubule, was bound to ferritin in cytoplasm.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (12 results)

All 2012 2011 2010 2009 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Book (1 results) Remarks (1 results)

  • [Journal Article] A Circadian Neuropeptide PDF in the Honeybee, Apis mellifera : cDNA Cloning and Expression of mRNA2012

    • Author(s)
      M.Sumiyoshi, S.Sato, Y.Takeda, K.Sumida, K.Koga, T.Itoh, H.Nakagawa, Y.Shimohigashi, M.Shimohigashi
    • Journal Title

      Zoological Science

      Volume: 28 Pages: 897-909

    • NAID

      40019134924

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Circadian Neuropeptide PDF in the Honeybee, Apis mellifera : cDNA Cloning and Expression of mRNA2011

    • Author(s)
      M. Sumiyoshi, S. Sato, Y. Takeda, K. Sumida, K. Koga, T. Itoh, H. Nakagawa, Y. Shimohigashi, M. Shimohigashi
    • Journal Title

      Zoological Science

      Volume: 28 Pages: 897-909

    • NAID

      40019134924

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neurite elongation from Drosophila neural BG2-c6 cells stimulated by 20-hydroxyecdysone2010

    • Author(s)
      M. Tominaga, E Nishihara, T. Oogami, M. Iwasaki, Y. Takagi, M. Shimohigashi and H. Nakagawa
    • Journal Title

      Neuroscience Letters

      Volume: 482 Pages: 250-254

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis and properties of fluorescence probe for detection of peroxides in mitochondria2010

    • Author(s)
      K. Shioji, Y. Oyama, K. Okuma and H. Nakagawa.
    • Journal Title

      Bioorganic Medical Chemistry Letters

      Volume: 20 Pages: 3911-3915

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neurite elongation from Drosophila neural BG2-c6 cells stimulated by 20-hydroxyecdysone.2010

    • Author(s)
      M.Tominaga, E Nishihara, T.Oogami, M.Iwasaki, Y.Takagi, M.Shimohigashi, H.Nakagawa
    • Journal Title

      Neuroscience Letters

      Volume: 482 Pages: 250-254

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis and properties of fluorescence probe for detection of peroxides in mitochondria.2010

    • Author(s)
      K.Shioji, Y.Oyama, K.Okuma, H.Nakagawa
    • Journal Title

      Bioorganic Medical Chemistry Letters

      Volume: 20 Pages: 3911-3915

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Movement of Ferritin Oligomers in Hepatoma Cells2009

    • Author(s)
      S. Koikawa, M. R. Hasan, M. Tominaga, S. Miyamoto, S. Kotani, H. Nakagawa.
    • Journal Title

      Science Journal of Kanagawa University

      Volume: 20 Pages: 77-80

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Iron Metabolism and Microtubule2009

    • Author(s)
      M. R. Hasan, H. Nakagawa, S. Kotani
    • Journal Title

      Science Journal of Kanagawa University

      Volume: 20 Pages: 1-9

    • NAID

      40016714873

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Movement of Ferritin Oligomers in Hepatoma Cells2009

    • Author(s)
      S Koikawa, MR Hasan, M Tominaga, S Miyamoto, S Kotani, H Nakagawa
    • Journal Title

      Science Journal of Kanagawa University 20

      Pages: 77-80

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Iron Metabolism and Microtubule2009

    • Author(s)
      MR Hasan, H Nakagawa, S Kotani
    • Journal Title

      Science Journal of Kanagawa University 20

      Pages: 1-9

    • NAID

      40016714873

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Book] Cytoskeleton of the Nervous System, Advances in Neurobiology 32011

    • Author(s)
      K. Tokuraku, K. Matsushima, H. Nakagawa and S. Kotani
    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://dx.doi.org/10.2108/zsj.28.897

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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