| Project/Area Number |
21570193
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cell biology
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| Research Institution | Tohoku University |
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Principal Investigator |
TANAKA Kozo 東北大学, 加齢医学研究所, 教授 (00304452)
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| Co-Investigator(Kenkyū-buntansha) |
YASUI Akira 東北大学, 加齢医学研究所, 教授 (60191110)
|
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| Research Collaborator |
ITOH Go 東北大学, 加齢医学研究所, 助教 (60607563)
KANNO Shinichiro 東北大学, 加齢医学研究所, 講師 (10400417)
TANAKA Tomoyuki 英国ダンディー大学, 生命科学科, 教授 (50227154)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 細胞周期 / 染色体分配 / 細胞分裂 / キネトコア / 微小管 |
|---|
| Research Abstract |
We searched for molecules involved in chromosomal stability, and identified a novel molecule, CAMP(chromosome alignment-maintaining phosphoprotein ; C13orf8, ZNF828). CAMP is supposed to contribute to chromosome segregation through the maintenance of kinetochore-microtubule attachment. Mutations in CAMP were suggested to be related to oncogenesis.
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