Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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Research Abstract |
We demonstrated that N-terminal domain of Sad1, an SPB component in S. pombe, is required for efficient re-accumulation of kinetochore components when cells return to mitotic cycle from meiotic cycle and thereby facilitate re-establishment of the centromere clustering at SPB. We also showed that inner nuclear membrane protein Ima1 has no apparent role in the centromere-SPB interaction, but instead is required for the formation and maintenance of nuclear membrane structure and the cell cycle progression.
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