| Project/Area Number |
21570222
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MINOKAWA Takuya 東北大学, 生命科学研究科, 准教授 (60400305)
WADA Hiroshi 筑波大学, 生命環境科学研究科, 教授 (60303806)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 棘皮動物 / ヨツアナカシパン / ハスノハカシパン / 体腔形成 / Hox遺伝子 / ウニ / 間接発生 / 直接発生 / 進化 / 小割球 / 発生調節遺伝子 / 小割球特異化 / タコノマクラ目 / 進化的変化 |
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| Research Abstract |
It is considered that, in echinoids, indirect development is the ancestral mode, and direct development has evolved independently in several lineages. To examine modifications of molecular mechanisms that drive the evolution of direct development, I analyzed expression patterns of the micromere specification genes in two sand dollars with distinct developmental modes. Between the two species, early expression patterns of the regulatory genes were largely conserved. After the mid blastula stage, however, a unique domain emerged in the direct developer, where either delta or hesC is not expressed. Since this region gives rise to mesenchyme cells which will form coelomic compartments, this modification may promote formation of adult structures in the direct developer.
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