Role of HtpG(Hsp90)in cyanobacterial adaptation to environmental stresses
| Project/Area Number |
21580083
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Saitama University |
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Principal Investigator |
NAKAMOTO Hitoshi 埼玉大学, 大学院・理工学研究科, 准教授 (30192678)
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| Co-Investigator(Renkei-kenkyūsha) |
KUMARU Penmetcha 産業技術総合研究所, 生物機能工学研究部門, 主任研究員 (80357938)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 微生物生態学 / 分子シャペロン / 応用微生物 / 環境 / ストレス / 進化 / シグナル伝達 |
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| Research Abstract |
We established the cyanobacterial HtpG-DnaK2-DnaJ2-GrpE chaperone machine. In this machine, HtpG, DnaK2 and DnaJ2 physically interacted each other. The heat-denatured protein substrates trapped by HtpG could be transferred to DnaK2 to be refolded. The present study indicated that HtpG forms a functional complex with DnaK2 and DnaJ2 to chaperone other proteins under environmental stresses
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Report
(4 results)
Research Products
(47 results)
