Study on Fatty liver induced by dietary oxycholesterols
Project/Area Number |
21580144
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Food science
|
Research Institution | Kyushu University |
Principal Investigator |
SATO Masao 九州大学, 農学研究院, 准教授 (90294909)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
Keywords | 酸化コレステロール / LXR / 脂肪肝 / 脂肪酸合成酵素 / SREBP1-c |
Research Abstract |
There is a question what kinds of oxycholesterol induce fatty liver. The answer is 7α-hydroxycholesterol and 4β-hydoroxycholesterol by the results from a detect system in which a reporter assay used with the promoter region of fatty acid synthase.
|
Report
(4 results)
Research Products
(16 results)