Mechanism of the anxiolytic effect of dietary vitamin E.
| Project/Area Number |
21580160
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Meiji University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KIKUSUI Takefumi 麻布大学, 獣医学部, 教授 (90302596)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 栄養生化学 / ビタミンE / トコフェロール / 不安行動 / トコフェロー / 不安 |
|---|
| Research Abstract |
Mechanism of the anxiolytic effect of dietary vitamin E was investigated. The results demonstrated that elevated oxidative stress disturbed the neurotransmission in the brain and increased glucocorticoid secretion from adrenal under stress, that may cause increased anxiety-like behavior. The results also showed that excess intake of dietary vitamin E could suppress anxiety-like behavior of rats.
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Report
(4 results)
Research Products
(57 results)
