Metabolism and antioxidant activity of serotonin derivatives
| Project/Area Number |
21580161
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Niigata Institute of Technology (2011)
Kagawa University (2009-2010) |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 抗酸化物質 / 体内動態 / 予防医学 / 食品機能科学 / 生活習慣病 / 生体内吸収 / 代謝物 / 食品機能化学 |
|---|
| Research Abstract |
Biological fate of two serotonin derivatives which prevent life-style related diseases were examined to evaluate antioxidant activity in vivo. These compounds were detected in rat blood plasma in their intact forms after oral administration, although their plasma concentrations were low levels. In contrast, high amount of metabolites derived from original serotonin derivatives were also detected in blood plasma suggesting possibility that these metabolites contribute prevention of life-style related diseases.
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Report
(4 results)
Research Products
(8 results)
