| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
The chemical instability of fish collagen, higher solubility to dilute acetic acid, indicates that the intermolecular cross-links in fish collagen differ from those in mammal collagen in quantity and/or quality. In fish, however, little information is available on the collagen cross-links, and the mechanism of cross-link formation has not been clear. To obtain the fundamental information on the regulatory mechanism of collagen-cross-linking pathway in fish, the author conducted cDNA cloning of fugu Takifugu rubripes LHs(LH1, 2a, 2b and 3) and performed expression analysis in the adult tissues and the embryos.
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