| Project/Area Number |
21580348
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Kobe University |
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Principal Investigator |
HONDA Kazuhisa 神戸大学, 大学院・農学研究科, 助教 (40335427)
|
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| Co-Investigator(Kenkyū-buntansha) |
ONOUE Satomi 静岡県立大学, 薬学部, 講師 (00457912)
|
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| Co-Investigator(Renkei-kenkyūsha) |
TACHIBANA Tetsuya 愛媛大学, 農学部, 准教授 (80346832)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
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| Keywords | 食欲 / ペプチド / 鶏 |
|---|
| Research Abstract |
Central administration ofα-MSH antagonist did not influenced food intake in broiler chicks, suggesting that endogenousα-MSH is decreased in the hypothalamus of broiler chicks. Central administration of CRF antagonist decreased plasma corticosterone and increased food intake in broiler chicks, suggesting that CRF antagonist acts as an orexigenic, antistress, and antiobesity peptide. However, these effects of CRF antagonist were observed in layer chicks, but not in broiler chicks, when the peptide administered intranasally. It is therefore likely that the rate of transportation of peptides from the nasal cavity to the central nervous system in broiler chicks is lower than that in layer chicks.
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