Effect of activin E on the prevention and therapy of metabolic syndrome.
| Project/Area Number |
21580370
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
|
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | インスリン感受性 / エネルギー代謝 / メタボリックシンドローム / 肝臓 / トランスジェニックマウス / 肥満 |
|---|
| Research Abstract |
To assess the role of activin E, a member of the transforming growth factor-ss superfamily in glucose/energy metabolism, we investigated the transcriptional regulation of activin E in the liver cells and the phenotype of transgenic mice over-expressing activin E. Activin E plays a pathophysiologicalrole in glucose/energy metabolism. The results should help identify the target for the prevention and therapy of metabolic syndrome.
|
Report
(4 results)
Research Products
(15 results)
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[Journal Article] Identification and characterization of canine growth differentiation factor-9 and its splicing variant2012
Author(s)
Hashimoto, O. Takagi, R., Yanuma, F., Doi, S., Shindo, J., Endo, H., Hasegawa, Y. and Shimasaki, S.
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Journal Title
Gene
Volume: 499
Pages: 266-272
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