A cell biological study of immunological diversity in bovine mammary tissue
Project/Area Number |
21580380
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied veterinary science
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Research Institution | Rakuno Gakuen University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
岩野 英知 酪農学園大学, 獣医学群, 准教授 (60382488)
中島 恵一 (独)農業・食品産業技術総合研究機構, 北海道農業研究センター, 主任研究員 (70362150)
小酒井 貴晴 山形大学, 地域教育文化学部, 准教授 (70391480)
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | ウシ / 乳房炎 / 乳腺上皮細胞 / 感染防御 / 乳房炎病原細菌 / ラクトフェリン / 好中球 / マクロファージ / 乳腺細胞 / 情報伝達系 / 黄色ブドウ球菌 / 免疫 / 三次元培養 / サイトカイン |
Research Abstract |
We created a cell culture model as a novel model of bovine mammary infection. Using this model, it was clarified that mammary epithelial cells recognized to date as milk-producing cells possess immunological diversity and are closely related to immunocompetent cells. The topic of this application is developmental research in preventative veterinary medicine and the findings are of great social significance to steady development of primary industry in Japan.
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Report
(4 results)
Research Products
(33 results)
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[Journal Article] A simplified PCR assay for fast and easy screening of Mycoplasma mastitis of dairy cattle2011
Author(s)
Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K, Ito, N., Yokota, H., Tamura, Y., Nagahata, H.
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Journal Title
J. Vet. Sci
Volume: 12
Pages: 191-193
Related Report
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[Journal Article] Analysis of Trace and Major Elements in Bronchoalveolar Lavage Fluid of Mycoplasma Bronchopneumonia in Calves2011
Author(s)
Suzuki, K., Higuchi, H., Iwano, H., Lakritz, J., Sera, K., Koiwa, M., Taguchi, K.
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Journal Title
Biol. Trace. Elem. Res
Volume: 145
Pages: 166-171
Related Report
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[Journal Article] A retrospective survey of the prevalence of complex vertebral malformation carriers in 9 Holstein dairy herds in Hokkaido, Japan2010
Author(s)
Nagahata, H., Nishiyama, T., Kanae, Y., Higuchi, H., Kawai, K., Endoh, D., Hayashi, M., Kurosawa, T.
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Journal Title
J. Vet. Med. Sci
Volume: 71
Pages: 793-795
NAID
Related Report
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[Journal Article] Effects of ammonia and hydrogen sulfide on physical and biochemical properties of the claw horn of Holstein cows2009
Author(s)
Higuchi, H., Kurumado, H., Mori, M., Degawa, A., Fujisawa, H., Kuwano, A. and Nagahata, H.
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Journal Title
Can. J. Vet. Res
Volume: 73
Pages: 15-20
Related Report
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[Journal Article] Comparison of serum lipid compositions, lipid peroxide,α-tocopherol and lipoproteins in captive marine mammals(bottlenose dolphins, spotted seals and West Indian manatees) and terrestrial mammals2009
Author(s)
Kasamatsu, M., Kawauchi, R., Tsunokawa, M., Ueda, K., Uchida, E., Oikawa, S., Higuchi, H., Kawajiri, T., Uchida, S. and Nagahata, H.
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Journal Title
Res. Vet. Sci
Volume: 86
Pages: 216-222
Related Report
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[Journal Article] Characterization of bacterial population of raw milk from bovine mastitis by culture-independent PCR-DGGE method2009
Author(s)
Kuang, Y., Tani, K., Synnott, A. J., Ohshima, K., Higuchi, H., Nagahata, H. and Tanji, Y.
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Journal Title
Biochemical Engineering Journal
Volume: 45
Pages: 76-81
NAID
Related Report
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[Journal Article] simplified PCR assay for fast and easy screening of Mycoplasma mastitis of dairy cattle
Author(s)
Higuchi, H., Iwano, H., Kawai, K., Ohta, T., Obayashi, T., Hirose, K, Ito, N., Yokota, H., Tamura, Y., Nagahata, H
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Journal Title
Journal of Veterinary Science
Volume: (in press)
Related Report
Peer Reviewed
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