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Anthelmintic resistance of bovine gastrointestinal nematodes to macrocyclic lactones in Japan

Research Project

Project/Area Number 21580382
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied veterinary science
Research InstitutionKitasato University

Principal Investigator

KUDO Noboru  北里大学, 獣医学部, 准教授 (20153306)

Co-Investigator(Kenkyū-buntansha) OYAMADA Takashi  北里大学, 獣医学部, 教授 (80050665)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords疾病予防・制御 / 牛 / 消化管内線虫 / 薬剤耐性 / イベルメクチン / LMIT
Research Abstract

Fecal egg count reduction tests using ivermectinpour-onformulation were conducted to investigate the prevalence of anthelmintic resistance in gastrointestinal nematodes on cattle farms in Aomori and Hokkaido, northernJapan, in 2009 and 2010.The egg count reductionsof predominant infecting nematodes, Cooperiaspp., were lower than90% on one farm in Aomori and two farms in Hokkaido after ivermectin treatment on August. The egg count reductions below 90% strongly suggest the presence of anthelmintic resistance. This is the first confirmation of ivermectin-resistantnematodes in cattle in Japan.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2012 2011

All Presentation (4 results)

  • [Presentation] 北海道の放牧牛におけるイベルメクチン製剤の消化管内線虫に対する駆虫効果2012

    • Author(s)
      工藤上、釜井莉佳, その他4名
    • Organizer
      第153回日本獣医学会学術集会
    • Place of Presentation
      大宮ソニックシティー(さいたま市)
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 北海道の放牧牛におけるイベルメクチン製剤の消化管内線虫に対する駆虫効果2012

    • Author(s)
      工藤上、釜井莉佳、横山萌美、小川俊彦、溝上まりえ、小山田隆
    • Organizer
      第153回日本獣医学会学術集会
    • Place of Presentation
      大宮
    • Related Report
      2011 Final Research Report
  • [Presentation] FECR試験によるイベルメクチン製剤の牛消化管内線虫に対する駆虫効果の検討2011

    • Author(s)
      工藤上、吉岡俊朗, 他7名
    • Organizer
      第151回日本獣医学会学術集会
    • Place of Presentation
      東京農工大学(東京都)
    • Year and Date
      2011-03-31
    • Related Report
      2010 Annual Research Report
  • [Presentation] FECR試験によるイベルメクチン製剤の牛消化管内線虫に対する駆虫効果の検討2011

    • Author(s)
      工藤上、吉岡俊朗、渡邉泰士、寺園有紀、武内信乃、堂之本琢人、中島健介、一杉香里、小山田隆
    • Organizer
      第151回日本獣医学会学術集会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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