The analysis of the cause gene in cattle with growth retardation and establishment of the gene diagnostic method

• Project/Area Number: 21580388
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Clinical veterinary science
• Research Institution: Gifu University
• Principal Investigator: OHBA Yasunori 岐阜大学, 応用生物科学部, 准教授 (20377691)
• Co-Investigator(Kenkyū-buntansha): KITAGAWA Hitoshi 岐阜大学, 応用生物科学部, 教授 (70144003) ; TAKASU Masaki 岐阜大学, 応用生物科学部, 准教授 (00503327)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 牛 / 発育不良 / 遺伝子

Research Abstract

It was suggested by analysis using the microsatellite DNA marker that the cause gene of growth retardation in cattle was, not only one, plural genes. As a result of micro-array analysis and real-time PCR, genetic expression to be related to lipid metabolism, cholesterol metabolism, and steroid metabolism significantly rose more than double in cattle with growth retardation in comparison with a normal. It was suggested that growth retardation in cattle is related with these genes.