| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
Leptospirosis is a zoonotic disease. Since the canine one may be lethal, it must be diagnosed in the early stage. However, there is no quick diagnostic method. A purpose of this study is developing a new convenient method for the canine leptospirosis. We identified fas1 and MaoC proteins as important antigens by analysis of leptospiral outer membrane proteins, and made latex beads for agglutination assays using their recombinant proteins. Our data suggest that this method is useful in the serological diagnosis of the canine leptospirosis.
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