Synthetic Studies on Marine Alkaloid of Batzellasides Directed toward Novel Antidiabetic Drug
Project/Area Number |
21590004
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Chemical pharmacy
|
Research Institution | University of Toyama |
Principal Investigator |
TOYOOKA Naoki 富山大学, 大学院・理工学研究部(工学), 教授 (10217565)
|
Co-Investigator(Kenkyū-buntansha) |
KATO Atsushi 富山大学, 大学病院, 准教授 (60303236)
ADACHI Isao 富山大学, 大学病院, 教授 (30151070)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 海洋産アルカロイド / バツェラサイド / 環状カーバメート / クロスメタセシス / Batzellaside / 相対配置 / 絶対配置 / 立体化学 / 海綿 / 不斉アリル化 / ジアステレオマー |
Research Abstract |
We have achieved the total synthesis of marine alkaloid of batzellaside B in 13 steps. Furthermore, batzellaside C, and their epimers have also been synthesized.
|
Report
(4 results)
Research Products
(6 results)