Development of novel sugar-related organic compounds utilized for the elucidation of life phenomenon.
| Project/Area Number |
21590021
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Teikyo University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 糖 / エーテル結合糖 / 糖尿病 / 糖鎖 / レベッカマイシン / グリコシル化 / SAM法 / PA化法 / Coyolosa / オキシラン |
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| Research Abstract |
In order to elucidate life phenomenon, novel sugar-related compounds(e. g., ether-linked sugars, Rebeccamycin derivatives) were efficiently synthesized. A new analytical method, which is utilizing SAM : Self-Assembled Monolayers, was also developed and was used for biological investigation.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] Identification of trimannoside-recognizing peptide sequences from a T7 phage deisplay screen using a QCM device2009
Author(s)
Nishiyama, Kazusa ; Takakusagi, Yoichi ; Kusayanagi, Tomoe ; Matsumoto, Yuki ; Habu, Shiori ; Kuramochi, Kouji ; Sugawara, Fumio ; Sakaguchi, Kengo ; Takahashi, Hideyo ; Natsugari, Hideaki ; Kobayashi, Susumu
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Journal Title
Bioloorganic & Medicinal Chemistry
Volume: 17
Pages: 195-202
Related Report
Peer Reviewed
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[Presentation] 医薬品と軸不斉2010
Author(s)
高橋秀依
Organizer
有機合成化学協会関東支部談話会
Place of Presentation
和光純薬湯河原研修所(神奈川県)
Year and Date
2010-09-17
Related Report
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