| Project/Area Number |
21590031
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyoto Pharmaceutical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUDA Hisashi 京都薬科大学, 薬学部, 准教授 (40288593)
NAKAMURA Seikou 京都薬科大学, 薬学部, 助教 (20411035)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | エジプト天然薬物 / メタボリックシンドローム / 伝承薬物 / 抗肥満作用 / 抗糖尿病作用 / PPARγアゴニスト様活性 / 3T3-L1細胞 / PPARγアゴニスト様活 / Anastatica hierochuntica / 分化誘導促進作用 / モロヘイヤ / マリアハンド |
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| Research Abstract |
We focused Egyptian traditional medicine and have researched the active constituents for therapeutics of metabolic syndrome. As the results, the extract and the constituents from Egyptian moroheiya(the leaves of Corchorus olitorius) were found to show an anti-diabetic(PPARγagonist-like) effect. In addition, many constituents were isolated from Egyptian traditional medicines, Anastatica hierochuntica, Citrullus colocynthis, Bryonia cretica, and Cyperus longus.
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