| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
The database constructed by the FDA Adverse Event Reporting System (AERS) was used in order to find some drugs which are more likely to causeStevens - Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) using data mining methods. Especially, we utilized association rule applying to the combinations of drugs in each patient. As a result of the mining, we constructed a new process to find significant suspect drugs. In addition we also revealed some chemical features which frequently exist in the suspect drugs.
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