Mechanism by which fatty acid binding proteins regulate the cellular signal transduction

• Project/Area Number: 21590215
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General anatomy (including Histology/Embryology)
• Research Institution: Yamaguchi University
• Principal Investigator: OWADA Yuji 山口大学, 大学院・医学系研究科, 教授 (20292211)
• Co-Investigator(Kenkyū-buntansha): TOKUDA Nobuko 山口大学, 大学院・医学系研究科, 准教授 (70227578)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 脂肪酸結合タンパク質 / 表皮細胞 / リンパ節 / 胸腺 / FABP / ケラチノサイト / アストロサイト / オリゴ前駆細胞 / オメガ3系脂肪酸 / 皮脂腺 / IL-7 / リノール酸 / 網膜 / 脳 / 樹状細胞 / M細胞

Research Abstract

In this study, we examined the role of fatty acid binding proteins in the regulation of cellular signal transduction, mainly by using FABP-deficient mice. The following results have been so far obtained :(1) epidermal-type FABP(FABP5) is involved in the early differentiation process of mouse keratinocytes though the regulation of linoleic acid metabolism(Ogawa et al., J Invest Dermatol, 2011).(2) brain-type FABP(FABP7) is involed in the proliferation of astrocytes through the regulation of omega-3 polyunsaturated fatty acid metabolism(Sharifi et al., Histochem Cell Biol, 2011).

Research Products

• [Journal Article] Reduced size of sebaceous gland and altered sebum lipid composition in mice deficient in the fatty acid-binding protein 5 gene (2012)
  • Author(s): Sugawara, T.*, Nemoto, K.*, Tokuda, N., Adachi, Y., Yamano, N., Muto, M., Okuyama, R., Sakai, S. and Owada, Y.
  • Journal Title: Exp Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Involvement of bone marrow-derived vascular progenitor cells in neovascularization during the corpus luteum formation in mice (2012)
  • Author(s): Kizuka, F., Tokuda, N., Takagi, K., Adachi, Y., Lee, L, Tamura, I., Maekawa, R., Taketani, T., Tamura, H., Suzuki, T., Owada, Y. and Sugino, N.
  • Journal Title: Biol Reprod Volume: (in press)
  • Peer Reviewed
• [Journal Article] Fatty acid-binding protein 4(FABP4) and FABP5 modulate cytokine production in the mouse thymic epithelial cells (2012)
  • Author(s): Adachi, Y.*, Hiramatsu, S.*, Tokuda, N., Sharifi, K., Ebrahimi, M, Islam, A, Kagawa, Y., Koshy, LV., Sawada, T., Hamano, K. and Owada, Y.
  • Journal Title: Histochem Cell Biol Volume: (in press)
  • Peer Reviewed
• [Journal Article] The effects of Fabp7 and Fabp5 on postnatal hippocampal neurogenesis in the mouse (2012)
  • Author(s): Matsumata, M., Sakayori, N., Maekawa, M., Owada, Y., Yoshikawa, T. and Osumi, N.
  • Journal Title: Stem Cells Volume: (in press)
  • Peer Reviewed
• [Journal Article] FABP7 expression in normal and stab injured brain cortex and its role in astrocyte proliferation (2011)
  • Author(s): Sharifi, K., Morihiro, Y., Maekawa, M., Yasumoto, Y., Hoshi, H., Adachi, Y., Sawada, T., Tokuda, N., Kondo, H., Yoshikawa, T., Suzuki, M. and Owada, Y.
  • Journal Title: Histochem Cell Biol Volume: 136 Pages: 501-13
  • Peer Reviewed
• [Journal Article] Role of polyunsaturated fatty acids and fatty acid binding protein in the pathogenesis of schizophrenia (2011)
  • Author(s): Maekawa, M., Owada, Y., and Yoshikawa, T.
  • Journal Title: Curr Pharm Des Volume: 17 Pages: 168-175
  • Peer Reviewed
• [Journal Article] Epidermal FABP(FABP5) regulates keratinocyte differentiation via 13(S)-HODE mediated activation of the NF-kB signaling pathway (2011)
  • Author(s): Ogawa, E.*, Owada, Y.*, Ikawa, S., Adachi, Y., Egawa, T., Nemoto, K., Suzuki, K., Hishinuma, T., Kawashima, H., Kondo, H., Muto, M., Aiba, S. and Okuyama, R.
  • Journal Title: J Invest Dermatol Volume: 131 Pages: 604-612
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies RNF213 as the first Moyamoya disease gene (2011)
  • Author(s): Kamada, F., Aoki, Y., Narisawa, A., Abe, Y., Komatsuzaki, S., Kikuchi, A., Kannno, J., Nihori, T., Ono, M., Ishii, N., Owada, Y., Fujimura, M., Mashimo, Y., Suzuki, Y., Hata, A., Tsuchiya, S., Tominaga, T., Matsubara, Y. and Kure, S.
  • Journal Title: J Human Genetics Volume: 56 Pages: 34-40
  • Peer Reviewed
• [Journal Article] 心臓型脂肪酸結合タンパク質による中枢ドパミン神経活動の調節 (2011)
  • Author(s): 山本由似、塩田倫史、大和田祐二、福永浩司
  • Journal Title: 薬学雑誌 Volume: 131 Pages: 497-502
  • NAID: 130000678828
  • Peer Reviewed
• [Journal Article] 脂肪酸結合蛋白質の新しい標的分子としてのドパミンD2受容体 (2011)
  • Author(s): 塩田倫史、山本由似、大和田祐二、福永浩司
  • Journal Title: 日本神経精神薬学雑誌 Volume: 31 Pages: 125-130
  • NAID: 10029094334
  • Peer Reviewed
• [Journal Article] Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions (2011)
  • Author(s): Fujii M, et al
  • Journal Title: Epilepsia Volume: 53 Issue: 3 Pages: 489-493
  • DOI: 10.1111/j.1528-1167.2011.03388.x
  • Peer Reviewed
• [Journal Article] FABP7 expression in normal and stab injured brain cortex and its role in astrocyte proliferation (2011)
  • Author(s): Sharifi K, et al
  • Journal Title: Histochemistry and Cell Biology Volume: 136 Pages: 501-513
  • Peer Reviewed
• [Journal Article] Role of polyunsaturated fatty acids and fatty acid binding protein in the pathogenesis of schizophrenia (2011)
  • Author(s): Maekawa M, et al
  • Journal Title: Current Pharmaceutical Design Volume: 17 Pages: 168-175
  • Peer Reviewed
• [Journal Article] Epidermal FABP (FABP5) regulates keratinocyte differentiation via 13(S)-HODE mediated activation of the NF-kB signaling pathway (2011)
  • Author(s): Ogawa E, et al
  • Journal Title: J Investigative Dermatology Volume: 131 Pages: 604-612
  • Peer Reviewed
• [Journal Article] Role of polyunsaturated fatty acids and fatty acid binding protein in the pathogenesis of schizophrenia. (2011)
  • Author(s): Maekawa M, et al.
  • Journal Title: Curr Pharm Des Volume: 17 Pages: 168-175
  • Peer Reviewed
• [Journal Article] Epidermal FABP (FABP5) regulates keratinocyte differentiation via 13(S)-HODE mediated activation of the NF-kB signaling pathway. (2011)
  • Author(s): Ogawa E, et al.
  • Journal Title: J Invest Dermatol Volume: 131 Pages: 604-612
  • Peer Reviewed
• [Journal Article] A genome-wide association study identifies RNF213 as the first Moyamoya disease gene. (2011)
  • Author(s): Kamada F, et al.
  • Journal Title: J Human Genetics Volume: 56 Pages: 34-40
  • Peer Reviewed
• [Journal Article] 心臓型脂肪酸結合タンパク質による中枢ドパミン神経活動の調節 (2011)
  • Author(s): 山本由似, 他
  • Journal Title: 薬学雑誌 Volume: 131 Pages: 492-502
  • Peer Reviewed
• [Journal Article] Identification of FABP7 in fibroblastic reticular cells of mouse lymph nodes (2010)
  • Author(s): Tokuda, N., Adachi, T., Adachi, Y., Higashi, M., Sharifi, K., Tuerxun, T., Sawada, T., Kondo, H. and Owada, Y.
  • Journal Title: Histochem Cell Biol Volume: 134 Pages: 445-452
  • Peer Reviewed
• [Journal Article] Localization of fatty acid binding proteins(FABPs) in the cochlea of mice (2010)
  • Author(s): Saino-Saito, S., Suzuki, R., Tokuda, N., Abe, H., Kondo, H. and Owada, Y.
  • Journal Title: Ann Anat Volume: 192 Pages: 210-214
  • Peer Reviewed
• [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor functions in mouse brain (2010)
  • Author(s): Shioda, N., Yamamoto, Y., Watanabe, M., Binas, B., Owada, Y. and Fukunaga, K.
  • Journal Title: J Neurosci Volume: 30 Pages: 3146-3155
  • Peer Reviewed
• [Journal Article] Polymorphism screening of brain-expressed FABPs7, 5 and 3 genes and association studies in autism and schizophrenia in Japanese subjects (2010)
  • Author(s): Maekawa, M., Iwayama, Y., Arai, R., Nakamura, K., Ohnishi, T., Osumi, N., Owada, Y., Mori, N. and Yoshikawa, T.
  • Journal Title: J Human Genetics Volume: 55 Pages: 127-130
  • Peer Reviewed
• [Journal Article] 脂肪酸結合蛋白質 (2010)
  • Author(s): 徳田信子、安達泰弘、澤田知夫、大和田祐二
  • Journal Title: 日本臨床 Volume: 68巻 Pages: 80-82
• [Journal Article] Identification of FABP7 in fibroblastic reticular cells of mouse lymph nodes. (2010)
  • Author(s): Tokuda N, et al.
  • Journal Title: Histochem Cell Biol Volume: 134 Pages: 445-452
  • Peer Reviewed
• [Journal Article] Localization of fatty acid binding proteins (FABPs) in the cochlea of mice. (2010)
  • Author(s): Saino-saito S, et al.
  • Journal Title: Ann Anat Volume: 192 Pages: 210-214
  • Peer Reviewed
• [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor functions in mouse brain. (2010)
  • Author(s): Shioda, N, et al.
  • Journal Title: J Neurosci 30 Pages: 3146-3155
  • Peer Reviewed
• [Journal Article] Localization of fatty acid binding protein of epidermal type(E-FABP) common to dendritic cells and presumptive macrophage in Peyer' s patches and epithelial M-cells of mouse intestine (2009)
  • Author(s): Suzuki, R., Nourani, MR., Saino-Saito, S., Abe, H., Nochi, T., Kiyono, H., Spener, F., Kondo, H. and Owada, Y.
  • Journal Title: Histochem Cell Biol Volume: 132 Pages: 577-584
  • Peer Reviewed
• [Journal Article] Discrete localization of various fatty acid binding proteins in different cell populations of mouse retina (2009)
  • Author(s): Saino-Saito, S., Nourani, MR., Iwasa, H., Kondo, H. and Owada, Y.
  • Journal Title: Cell Tissue Res Volume: 338 Pages: 191-201
  • Peer Reviewed
• [Journal Article] Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses (2009)
  • Author(s): Maekawa, M., Takashima, N., Matsumata, M., Ikegami, S., Kontani, M., Hara, Y., Kawashima, H., Owada, Y., Kiso, Y., Yoshikawa, T., Inokuchi, K. and Osumi, N.
  • Journal Title: PLoS ONE Volume: 4 Pages: 5085-5085
  • Peer Reviewed
• [Journal Article] Cysteinyl leukotrienes enhance the degranulation of bone marrow-derived mast cells through the autocrine mechanism (2009)
  • Author(s): Kaneko, I., Suzuki, K., Matsuo, K., Kumagai, H., Owada, Y., Noguchi, N., Hishinuma, T. and Ono, M.
  • Journal Title: Tohoku J Exp Med Volume: 217 Pages: 185-91
  • Peer Reviewed
• [Journal Article] 高次脳機能における心臓型脂肪酸結合タンパク質の役割 (2009)
  • Author(s): 本橋慧樹、山本由似、塩田倫史、近藤尚武、大和田祐二、福永浩司
  • Journal Title: 薬学雑誌 Volume: 129巻 Pages: 191-195
  • NAID: 110007046096
  • Peer Reviewed
• [Journal Article] 免疫系細胞によるFABP分子群の発現と機能 (2009)
  • Author(s): 徳田信子、安達泰弘、澤田知夫、大和田祐二
  • Journal Title: 時間学研究 Volume: 3巻 Pages: 49-57
• [Journal Article] Discrete localization of various fatty acid binding proteins in different cell populations of mouse retina. (2009)
  • Author(s): Saino-Saito, S, et al.
  • Journal Title: Cell Tissue Res 338 Pages: 191-201
  • Peer Reviewed
• [Journal Article] Localization of fatty acid binding protein of epidermal type (E-FABP) common to dendritic cells and presumptive macrophage in Peyer's patches and epithelial M-cells of mouse intestine. (2009)
  • Author(s): Suzuki, R, et al.
  • Journal Title: Histochem Cell Biol 132 Pages: 577-584
  • Peer Reviewed
• [Presentation] 脂肪酸結合タンパク質による脳の脂質代謝制御とヒト精神疾患との関連 (2012)
  • Author(s): 大和田祐二
  • Organizer: 第89回日本生理学会大会
  • Place of Presentation: 信州大学(松本)
  • Year and Date: 2012-03-30
• [Presentation] 脂肪酸結合タンパク質による脳の脂質代謝制御とヒト精神疾患との関連 (2012)
  • Author(s): 大和田祐二
  • Organizer: 第89回日本生理学会
  • Place of Presentation: 信州大学松本市
  • Year and Date: 2012-03-30
• [Presentation] 皮脂腺における脂肪酸結合タンパク質(FABP5)の局在と機能 (2012)
  • Author(s): 山野希、徳田信子、堀啓一、根本圭、安達泰弘、澤田知夫、大和田祐二
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-28
• [Presentation] Localization of fatty acid binding protein in mouse placenta and its possible role of fatty acid transport through trophoblasts (2012)
  • Author(s): Islam, A., Tokuda, N., Adachi, Y., Sawada, T., and Owada, Y.
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-28
• [Presentation] Localization of fatty acid binding protein in mouse placenta and its possible role of fatty acid transport through trophoblasts (2012)
  • Author(s): Ariful Islam, ら
  • Organizer: 第117回日本解剖学会総会
  • Place of Presentation: 山梨大学甲府市
  • Year and Date: 2012-03-28
• [Presentation] 皮脂腺における脂肪酸結合タンパク質(FABP5)の局在と機能 (2012)
  • Author(s): 山野希, ら
  • Organizer: 第117回日本解剖学会総会
  • Place of Presentation: 山梨大学甲府市
  • Year and Date: 2012-03-28
• [Presentation] FABP7 in astrocytes is involved in control of neuronal dendritic formation (2012)
  • Author(s): Ebrahimi, M., Kagawa, Y., Sharifi, K., Adachi, Y., Sawada, T., Tokuda, N., and Owada, Y.
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-27
• [Presentation] 肝クッパー細胞における脂肪酸結合蛋白質(FABP7)の発現とサイトカイン産生への関与 (2012)
  • Author(s): 宮崎啓史、澤田知夫、原田美紀、清平美和、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-27
• [Presentation] 肝クッパー細胞における脂肪酸結合蛋白質の発現とサイトカイン産生への関与 (2012)
  • Author(s): 宮崎啓史, ら
  • Organizer: 第117回日本解剖学会総会
  • Place of Presentation: 山梨大学甲府市
  • Year and Date: 2012-03-27
• [Presentation] FABP7 in astrocytes is involved in control of neuronal dendritic formation (2012)
  • Author(s): Majid Ebrahimi, ら
  • Organizer: 第117回日本解剖学会総会
  • Place of Presentation: 山梨大学甲府市
  • Year and Date: 2012-03-27
• [Presentation] 脂肪酸結合タンパク質による神経機能の制御 (2012)
  • Author(s): 大和田祐二
  • Organizer: 第117回日本解剖学会総会・全国学術集会
  • Place of Presentation: 山梨大学(甲府)
  • Year and Date: 2012-03-26
• [Presentation] 脂肪酸結合タンパク質による神経機能の制御 (2012)
  • Author(s): 大和田祐二
  • Organizer: 第117回日本解剖学会総会
  • Place of Presentation: 山梨大学甲府市
  • Year and Date: 2012-03-26
• [Presentation] 肪酸結合蛋白質(FABP7)は肝クッパー細胞の機能を修飾する (2011)
  • Author(s): 宮崎啓史、澤田知夫、清平美和、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第40回日本免疫学会学術集会
  • Place of Presentation: 幕張メッセ(千葉)
  • Year and Date: 2011-11-28
• [Presentation] 脂肪酸結合蛋白質(FABP7)は肝クッパー細胞の機能を修飾する (2011)
  • Author(s): 宮崎啓史, ら
  • Organizer: 第40回日本免疫学会総会
  • Place of Presentation: 幕張メッセ幕張市
  • Year and Date: 2011-11-28
• [Presentation] Altered morphology of neurons in FABP7-deficient mixed cortical culture (2011)
  • Author(s): Ebrahimi, M., Kagawa, Y., Sharifi, K., Nawata, T., Adachi, Y., Sawada, T., Tokuda, N., and Owada, Y.
  • Organizer: 第66回日本解剖学会中国・四国支部学術集会
  • Place of Presentation: 徳島大学(徳島)
  • Year and Date: 2011-11-12
• [Presentation] Localization of fatty acid binding proteins in mouse placenta (2011)
  • Author(s): Islam, A., Tokuda, N., Adachi, Y., Sawada, T., and Owada, Y.
  • Organizer: 第66回日本解剖学会中国・四国支部学術集会
  • Place of Presentation: 徳島大学(徳島)
  • Year and Date: 2011-11-12
• [Presentation] Expression of FABP7 in normal and injured brain cortex and its role in astrocyte proliferation (2011)
  • Author(s): Sharifi, K., Morihiro, Y., Yasumoto, Y., Maekawa, M., Ebrahim, M., Tokuda, N., Yoshikawa, T., and Owada, Y.
  • Organizer: 第34回日本神経科学会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-09-16
• [Presentation] Expression of FABP7 in normal and injured brain cortex and its role in astrocyte proliferation (2011)
  • Author(s): Kazem Sharifi, ら
  • Organizer: 第34回日本神経科学会
  • Place of Presentation: パシフィコ横浜横浜市
  • Year and Date: 2011-09-16
• [Presentation] 脂肪酸結合蛋白質FABP7によるクッパー細胞のサイトカイン産生制御 (2011)
  • Author(s): 宮崎啓史、澤田知夫、清平美和、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第23回日本比較免疫学会学術集会
  • Place of Presentation: 独立行政法人海洋研究開発機構(横浜)
  • Year and Date: 2011-08-21
• [Presentation] 脂肪酸結合タンパク質(FABP7)は肝クッパー細胞(KC)の機能制御を介して肝傷害過程に関わる (2011)
  • Author(s): 清平美和、宮崎啓史、澤田知夫、原田美紀、安達泰弘、徳田信子、大和田祐二
  • Organizer: 第116回山口大学医学会学術講演会
  • Place of Presentation: 山口大学(宇部)
  • Year and Date: 2011-07-16
• [Presentation] FABP5 regulates karatinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB pathway (2011)
  • Author(s): Adachi, Y., Okuyama, R., and Owada, Y.
  • Organizer: 第30回内藤コンファレンス
  • Place of Presentation: シャトレーゼガトーキングダムサッポロ(札幌)
  • Year and Date: 2011-06-28
• [Presentation] 脳型脂肪酸結合タンパク質(FABP7)のアストロサイトにおける機能 (2011)
  • Author(s): 安本有希、Kazem Sharifi、森廣雄介、安達泰弘、徳田信子、澤田知夫、大和田祐二
  • Organizer: 第115回日本解剖学会総会
  • Place of Presentation: 岩手県民会館(盛岡)
  • Year and Date: 2011-03-29
• [Presentation] 脳の脂質恒常性維持における脂肪酸結合タンパク質の役割 (2011)
  • Author(s): 大和田祐二
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-28
• [Presentation] リンパ内のfibroblastic reticular cellにおける脳型脂肪酸結合タンパク質(FABP7)の局在解析 (2011)
  • Author(s): 徳田信子、安達泰弘、安達利昭、東麻由美、Kazem Sharifi、Tuerhong Tuerxun、澤田知夫、大和田祐二
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-28
• [Presentation] 脂肪酸結合タンパク質(FABP5)は脂肪酸代謝産物13(S)-HODEによるNF-κBシグナル伝達の調節を介して表皮細胞分化を制御する (2011)
  • Author(s): 安達泰弘、根本圭、徳田信子、澤田知夫、奥山隆平、大和田祐二
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-28
• [Presentation] FABP7 expression in injured brain cortex and its role in astrocyte proliferation (2011)
  • Author(s): Kazem Sharifi, Yuki Yasumoto, Yasuhiro Adachi, Tuerhong Tuerxun, Ariful Islam, , Majid Ebrahimi, Tomoo Sawda, Nobuko Tokuda, Yuji Owada
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-28
• [Presentation] 脂肪酸結合タンパク質(FABP7)はクッパー細胞の貪食能を介して肝傷害過程に関わる (2011)
  • Author(s): 清平美和、澤田知夫、宮崎啓史、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: パシフィコ横浜(横浜)
  • Year and Date: 2011-03-28
• [Presentation] 脳の脂質恒常性維持における脂肪酸結合タンパク質の役割 (2011)
  • Author(s): 大和田, 祐二
  • Organizer: 第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
  • Place of Presentation: (J Physiol Sci誌上開催)
  • Year and Date: 2011-03-27
• [Presentation] 脳の脂質恒常性と神経精神疾患～脂質結合タンパク質の役割～ (2010)
  • Author(s): 大和田祐二
  • Organizer: 第7回九州・山口脳循環代謝フォーラム
  • Place of Presentation: ホテルオークラ(福岡)
  • Year and Date: 2010-12-17
• [Presentation] 脳の脂質恒常性と神経精神疾患-脂質結合タンパク質の役割 (2010)
  • Author(s): 大和田, 祐二
  • Organizer: 第88回九州・山口脳循環代謝フォーラム
  • Place of Presentation: 福岡ホテルオークラ博多
  • Year and Date: 2010-12-17
• [Presentation] Quanta3D・LSM510META・FC500を用いたマウスリンパ節内の脂肪酸結合タンパク質(FABP)サブタイプの局在解析 (2010)
  • Author(s): 徳田信子、安達泰弘、安達利昭、東麻由美、澤田知夫、有働公一、大和田祐二
  • Organizer: 総合科学実験センター平成22年度第2回研究発表会
  • Place of Presentation: 山口大学(山口)
  • Year and Date: 2010-12-14
• [Presentation] クッパー細胞の活性制御における脂肪酸結合タンパク質(FABP7)の関与 (2010)
  • Author(s): 澤田知夫、清平美和、宮崎啓史、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第65回日本解剖学会中国・四国支部学術集会
  • Place of Presentation: 広島国際大学(呉)
  • Year and Date: 2010-10-10
• [Presentation] 脂肪酸結合タンパク質(FABP7)のクッパー細胞における発現とその意義 (2010)
  • Author(s): 澤田知夫、中村啓二、中原有海、清平美和、徳田信子、安達泰弘、大和田祐二
  • Organizer: 第22回日本比較免疫学会学術集会
  • Place of Presentation: 九州大学(福岡)
  • Year and Date: 2010-08-04
• [Presentation] リンパ節内の脂肪酸結合蛋白質(FABP)サブタイプの局在解析 (2010)
  • Author(s): 徳田信子、東麻由美、安達利昭、安達泰弘、澤田知夫、大和田祐二
  • Organizer: 第115回日本解剖学会総会
  • Place of Presentation: 岩手県民会館(盛岡)
  • Year and Date: 2010-03-30
• [Presentation] マウス胸腺上皮細胞での液性因子産生における脂肪細胞型脂肪酸結合タンパク質(FABP4)の機能 (2010)
  • Author(s): 安達泰弘、平松澄恵、徳田信子、澤田知夫、大和田祐二
  • Organizer: 第115回日本解剖学会総会
  • Place of Presentation: 岩手県民会館(盛岡)
  • Year and Date: 2010-03-29
• [Presentation] シンポジウム「解剖学の進歩-精神機能との関連」:FABP分子群の神経系における機能-精神疾患との関連について- (2009)
  • Author(s): 大和田祐二
  • Organizer: 日本解剖学会第64回中国・四国支部学術集会
  • Place of Presentation: 高知大学(南国)
  • Year and Date: 2009-10-25
• [Presentation] FABP7の肝傷害過程における発現の意義 (2009)
  • Author(s): 徳田信子、澤田知夫、中村啓二、中原有海、清平美和、安達泰弘、大和田祐二
  • Organizer: 日本解剖学会第64回中国・四国支部学術集会
  • Place of Presentation: 高知大学(南国)
  • Year and Date: 2009-10-25
• [Presentation] 表皮細胞の分化における表皮型脂肪酸結合タンパク質(FABP5)の関与 (2009)
  • Author(s): 安達泰弘、根本圭、徳田信子、澤田知夫、大和田祐二
  • Organizer: 日本解剖学会第64回中国・四国支部学術集会
  • Place of Presentation: 高知大学(南国)
  • Year and Date: 2009-10-25
• [Presentation] 脳の脂質恒常性と精神疾患 (2009)
  • Author(s): 大和田祐二
  • Organizer: 日本解剖学会中国四国地区連合会
  • Place of Presentation: 南国市
  • Year and Date: 2009-10-24
• [Presentation] FABP7の肝傷害過程における時間的発現変化の意義 (2009)
  • Author(s): 徳田信子、澤田知夫、中村啓二、中原有海、清平美和、安達利昭、安達泰弘、大和田祐二
  • Organizer: 日本時間学会第1回大会
  • Place of Presentation: 山口大学(山口)
  • Year and Date: 2009-06-13
• [Presentation] 脂肪酸結合タンパク質(FABP7)のクッパー細胞における発現とその意義 (2009)
  • Author(s): 澤田知夫、中村啓二、中原有海、清平美和、徳田信子、安達泰弘、大和田祐二
  • Organizer: 日本比較免疫学会第21回学術集会
  • Place of Presentation: 日本大学(藤沢)
• [Remarks]
  • URL: http://ds.cc.yamaguchi-u.ac.jp/~org-anat/