Analyses of novel genes expressed in the embryonic spinal cord with reference to the sensory axonal guidance
| Project/Area Number |
21590218
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
KAI Nobuyuki 福島県立医科大学, 医学部, 助教 (50301750)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 細胞・組織 / 発生・分化 / 神経科学 / 脳・神経 / 派生・分化 / マイクロアレイ |
|---|
| Research Abstract |
During early development, the dorsal spinal cord-derived cue chemoattracts dorsal root ganglion(DRG) axons toward the dorsal root entry zone. To identify the molecular nature of this chemoattraction, we examined the function of novel genes expressed in the embryonic dorsal spinal cord. We revealed that a protein encoded by mouse Fukushima 1(mF1) exerted an attractive activity for DRG axons. These results suggest that mF1 may be a candidate for the dorsal spinal cord-derived attractant.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons2011
Author(s)
Kenta Kobayashi, Tomoyuki Masuda, Masanori Takahashi, Jun-ichi Miyazaki, Masahiro Nakagawa, Motokazu Uchigashima, Masahiko Watanabe, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi
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Journal Title
European Journal of Neuroscience
Volume: 33(4)
Pages: 612-621
Related Report
Peer Reviewed
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[Journal Article] Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons.2011
Author(s)
Kenta Kobayashi, Tomoyuki Masuda, Masanori Takahashi, Junichi Miyazaki, Masahiro Nakagawa, Motokazu Uchigashima, Masahiko Watanabe, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi
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Journal Title
European Jourbal of Neuroscience
Volume: 33
Pages: 612-621
Related Report
Peer Reviewed
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[Presentation] 羊膜類の体幹部末梢神経系の進化2011
Author(s)
川口将史, 渡邊愛己, 真喜屋宏美, 長島寛, 川崎能彦, 平田たつみ, 増田知之, 倉谷滋, 村上安則
Organizer
第34回日本神経科学大会
Place of Presentation
神奈川
Year and Date
2011-09-16
Related Report
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[Presentation] 羊膜類の体幹部末梢神経系の進化2011
Author(s)
川口将史, 渡邊愛己, 真喜屋宏美, 長島寛, 川崎能彦, 平田たつみ, 増田知之, 倉谷滋, 村上安則
Organizer
第34回日本神経科学大会
Place of Presentation
神奈川県横浜市
Year and Date
2011-09-16
Related Report
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[Book] 生物学大辞典2010
Author(s)
増田知之, 編集代表者 石川統
Total Pages
1634
Publisher
東京化学同人社
Related Report
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