| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
To elucidate physiological functions of multiple cells or organs exsising deep inside body, we developed a branch-type fiber-coupled confocal microscope(FCM). The spatio-temporal performance of FCM was enough to resolve the fluorescently-labelled granules in the pancreaticβcells. By using FCM, we could measure glucose-dependent fluorescent intensity changes in theβ-granules reflecting secretion of insulin to the blood stream. The FCM may be usefull technique for the understanding of mechanisms or disorders controlling of the blood glucose level.
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