A Study on the Photosensitive Properties of Retinal Ganglion Cell

• Project/Area Number: 21590262
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental physiology (including Physical medicine and Nutritional physiology)
• Research Institution: Tokai University
• Principal Investigator: TAKAO Motoharu 東海大学, 情報理工学部, 准教授 (90408013)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 網膜神経節細胞 / 錐体視細胞 / 局所神経回路 / 光同調 / 概日リズム / 視細胞 / 生理学 / メラノプシン / 光感受性網膜神経節細胞 / 分光波長感度特性

Research Abstract

Intrinsically photosensitive retinal ganglion cell, a subset of retinal ganglion cell, was found to mediate circadian photoentrainment ten years ago. The detailed local circuit is still largely unknown. In this study, I found the synapses between intrinsically photosensitive retinal ganglion cell and cone bipolar cells. The synaptic inputs from cones enable the intrinsically photosensitive retinal ganglion cell to respond to wide range of light spectrum.

Research Products

• [Journal Article] 情報系学生を対象とした神経科学体験実習講座の試み (2012)
  • Author(s): 高雄元晴
  • Journal Title: 東海大学情報理工学部紀要 Volume: 11 Pages: 55-58
  • Peer Reviewed
• [Journal Article] A pilot experiment on spectral sensitivity of the suprachiasmatic nucleus (2011)
  • Author(s): Koga Y., Takao, M., Murata T., Ide N.
  • Journal Title: The Proceedings of the 27the session of the CIE Volume: 27 Pages: 504-509
  • Peer Reviewed
• [Journal Article] もっと朝の光を、夜の闇を (2011)
  • Author(s): 高雄元晴
  • Journal Title: 望星 Volume: 42 Pages: 33-38
• [Journal Article] A Pilot Experiment on Spectral Response Sensitivity of The Suprachiasmatic Nucleus (The Chief Circadian Pacemaker) (2011)
  • Author(s): Koga, Y., et al
  • Journal Title: Proc.of the 27^<th> Session of the CIE Volume: 1 Pages: 504-509
  • Peer Reviewed
• [Journal Article] ソウル大会:オーラルセツションに参加して (2011)
  • Author(s): 高雄元晴
  • Journal Title: 照明学会誌 Volume: 95 Pages: 100-102
• [Journal Article] Ethnic differences in the infant's photoenvironmental effect on morningness-eveningness (2010)
  • Author(s): Takao M
  • Journal Title: The Proceedings of the Lighting Symposium of China, Japan and Korea Volume: 3 Pages: 59-62
  • Peer Reviewed
• [Journal Article] Ethnic differences in the infant's photoenvironmental effect on morningness-eveningness. (2010)
  • Author(s): 高雄元晴
  • Journal Title: The Proceedings of the Lighting Symposium of China, Japan and Korea. Volume: 3 Pages: 59-62
  • Peer Reviewed
• [Journal Article] Photoperiod at birth does not modulate the diurnal preference in Asian population (2009)
  • Author(s): Takao M., Kurachi T., Kato K.
  • Journal Title: Chronobiology International Volume: 26 Pages: 1470-1477
  • Peer Reviewed
• [Journal Article] Addictive Personality and Problematic Nobile Phone Use (2009)
  • Author(s): Takao M., Takahashi S., Kitamura M.
  • Journal Title: CyberPsychology & Behavior Volume: 12 Pages: 501-507
  • Peer Reviewed
• [Journal Article] Polychromatic properties of the pupillary light reflex in human subjects (2009)
  • Author(s): Takao M., Koga Y.
  • Journal Title: Proceedings af Lux Europa Volume: 11 Pages: 313-316
  • Peer Reviewed
• [Journal Article] Ectopic synaptic ribbons in dendrites of mouse retinal ON-and OFF-bipolar cells (2009)
  • Author(s): Ishii M, Morigiwa K, Takao M, Nakanishi S, Fukuda Y, Mimura O, Fukuda Y.
  • Journal Title: Cell & Tissue Research Volume: 338 Pages: 355-375
  • Peer Reviewed
• [Journal Article] 視覚と生体リズム (2009)
  • Author(s): 高雄元晴
  • Journal Title: 東海大学情報理工学部紀要 Volume: 9 Pages: 29-40
  • Peer Reviewed
• [Journal Article] Photoperiod at birth does not modulate the diurnal preference in Asianpopulation. (2009)
  • Author(s): Takao M., Kurachi T., Kato K.
  • Journal Title: Chronobiology International 26 Pages: 1470-1477
  • Peer Reviewed
• [Journal Article] Addictive Personality and Problematic Nobile Phone Use. (2009)
  • Author(s): Takao M., Takahashi S., Kitamura M.
  • Journal Title: CyberPsychology & Behavior 12 Pages: 501-507
  • Peer Reviewed
• [Journal Article] Polychromatic properties of the pupillary light reflex in human subjects. (2009)
  • Author(s): Takao M., Koga Y.
  • Journal Title: Proceedings af Lux Europa 11 Pages: 313-316
  • Peer Reviewed
• [Journal Article] Ectopic synaptic ribbons in dendrites of mouse retinal ON- and OFF-bipolar cells. (2009)
  • Author(s): Ishii M, Morigiwa K, Takao M, Nakanishi S, Fukuda Y, Mimura O, Fukuda Y.
  • Journal Title: Cell & Tissue Research 338 Pages: 355-375
  • Peer Reviewed
• [Journal Article] 視覚と生体リズム (2009)
  • Author(s): 高雄元晴
  • Journal Title: 東海大学情報理工学部紀要 9 Pages: 29-40
  • Peer Reviewed
• [Presentation] 非イメージ形成の視覚の分光感度-覚醒に関わる神経核の応答- (2011)
  • Author(s): 井手渚紗, 御厨藍, 古賀靖子, 高雄元晴
  • Organizer: 平成23年度(第43回)照明学会全国大会講演論文集
  • Year and Date: 2011-09-15
• [Presentation] Fm theta brain wave activity during plastic model building (2011)
  • Author(s): Takao M, Kadota Y, Yamagami M, Taniuchi J, Masuda N, Shimizu H, Kamei T
  • Organizer: The 8th IBRO(International Brain Research Organization) World Congress of Neuroscience
  • Year and Date: 2011-07-15
• [Presentation] A pilot experiment on spectral sensitivity of the suprachiasmatic nucleus (2011)
  • Author(s): Koga Y., Takao, M., Murata T., Ide N.
  • Organizer: The 27 the session of the CIE
  • Year and Date: 2011-07-12
• [Presentation] プラモデル作製時における脳活動の研究-Fmθ波出現動態について- (2011)
  • Author(s): 高雄元晴
  • Organizer: 電子情報通信学会大会
  • Place of Presentation: 東京都市大学
  • Year and Date: 2011-03-14
• [Presentation] 人間の記憶特性を考慮した「覚えやすく、見破られにくい」パスワード生成アルゴリズムの提案 (2011)
  • Author(s): 高雄元晴
  • Organizer: テクニカルショウヨコハマ2011
  • Place of Presentation: パシフィコ横浜
• [Presentation] Ethnic differences in the infant's photoenvironmental effect on morningness-eveningness (2010)
  • Author(s): Takao M
  • Organizer: The 3rd. Lighting Symposium of China, Japan and Korea
  • Year and Date: 2010-09-29
• [Presentation] Ethnic differences in the infant's photoenvironmental effect on morning ness-eveningness. (2010)
  • Author(s): 高雄元晴
  • Organizer: The 3rd Lighting Symposium of China, Japan and Korea.
  • Place of Presentation: ソウル市COEX
  • Year and Date: 2010-09-29
• [Presentation] 非イメージ形成の視覚の分光感度-生物時計の光感受性- (2010)
  • Author(s): 井手渚紗, 古賀靖子, 高雄元晴
  • Organizer: 平成22年度(第43回)照明学会全国大会講演論文集
  • Year and Date: 2010-09-07
• [Presentation] 概日リズムの光同調評価装置の試作 (2010)
  • Author(s): 高雄元晴, 古賀靖子
  • Organizer: 広域医療連携研究会
  • Year and Date: 2010-06-12
• [Presentation] 概日リズムの光同調評価装置の試作 (2010)
  • Author(s): 高雄元晴・古賀靖子
  • Organizer: 広域連携医療ネットワークシステム研究会
  • Place of Presentation: 明電舎沼津事業所
  • Year and Date: 2010-06-12
• [Presentation] 非イメージ形成の視覚の分光感度-生物時計の光感受性- (2010)
  • Author(s): 井手渚沙・古賀靖子・高雄元晴
  • Organizer: 照明学会
  • Place of Presentation: 大阪市立大学
• [Presentation] Polychromatic properties of the pupillary light reflex in human subjects (2009)
  • Author(s): Takao M., Koga Y.
  • Place of Presentation: Lux Europa
  • Year and Date: 2009-09-09
• [Presentation] Polychromatic properties of the pupillary light reflex in human subjects. (2009)
  • Author(s): Takao M., Koga Y.
  • Organizer: Lux Europa
  • Place of Presentation: トルコ共和国イスタンブール県
  • Year and Date: 2009-09-09
• [Presentation] ヒトの覚醒水準に与える単波長光の効果に関する研究 (2009)
  • Author(s): 岩田利枝, 高雄元晴, 上田稲太
  • Organizer: 平成21年度(第42回)照明学会全国大会講演論文集
  • Year and Date: 2009-08-28
• [Presentation] 非イメージ形成の視覚の分光感度暗順応状態における瞳孔反射 (2009)
  • Author(s): 古賀靖子, 高雄元晴, 天野蓉子
  • Organizer: 照明学会全国大会講演論文集
  • Year and Date: 2009-08-28
• [Presentation] 非イメージ形成の視覚の分光感度-覚醒に関わる神経核の応答-
  • Author(s): 井手, ら
  • Organizer: 照明学会
  • Place of Presentation: 愛媛大学
• [Book] 神経情報科学入門 (2009)
  • Author(s): 高雄元晴, 他4名
  • Total Pages: 208
  • Publisher: コロナ社
• [Book] 神経情報科学入門 (2009)
  • Author(s): 高雄元晴
  • Total Pages: 208
  • Publisher: コロナ社
• [Remarks]
  • URL: http://www.licht-iprgc.org