| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Excretion at the tissue and organs bordering on external side of the body has a role as a host-defense function against xenobiotics and, then, it's failure could cause diseases. Identification of the corresponding molecular factors and elucidation of the underlying molecular mechanisms is indispensable for diagnosis and treatment of the diseases. In this study, (1) we identified some of the molecular factors which could be a target for cancer treatment, and (2) found that inhibitor of the xenobiotics transporter could be useful as a chemoprevention agent.
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