Significance of Annexin A5 in atherothrombosis
| Project/Area Number |
21590374
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Human pathology
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MARUTSUKA Kosuke 宮崎大学, 医学部, 准教授 (00239154)
HATAKEYAMA Kinta 宮崎大学, 医学部, 講師 (60325735)
YAMASHITA Atsushi 宮崎大学, 医学部, 助教 (90372797)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 人体病理 / 血栓 / 動脈硬化 / Annexin A5 / アテローム血栓症 / アネキシンA5 / 血栓症 |
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| Research Abstract |
We studied the immunohistochemical study or PCR study of annexin A5 in thrombosis. No apparent annexin A5 was detected in thrombi by immunohistochemical study or PCR study. Next, we examined the annexin A5 by flow chamber study and rabbit thrombosis model. No annexin A5 was detected in these models. Annexin A5 was not associated with thrombosis.
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Report
(4 results)
Research Products
(50 results)
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[Journal Article] Human C-reactive protein enhances thrombus formation after neointimal balloon injury in transgenic rabbits.2011
Author(s)
Matsuda S, Yamashita A, Sato Y, Kitajima S, Koike T, Sugita C, Moriguchi-Goto S, Hatakeyama K, Takahashi M, Koshimoto C, Matsuura Y, Iwakiri T, Chen YE, Fan J, Asada Y
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Journal Title
J Thromb Haemost
Volume: 9
Pages: 201-208
Related Report
Peer Reviewed
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[Journal Article] Inhibition of factor XI reduces thrombus formation in rabbit jugular vein under endothelial denudation and/or blood stasis2010
Author(s)
Takahashi M, Yamashita A, Moriguchi-Goto S, Sugita C, Matsumoto T, Matsuda S, Sato Y, Kitazawa T, Hattori K, Shima M, Asada Y
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Journal Title
Thromb Res
Volume: 125
Pages: 464-70
Related Report
Peer Reviewed
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[Journal Article] Plasma Pentraxin 3, but not high-sensitivity C-reactive protein, is a useful inflammatory biomarker for predicting cognitive impairment in elderly hypertensive patients2010
Author(s)
Yano Y, Matsuda S, Hatakeyama K, Sato Y, Imamura T, Shimada K, Kodama T, Kario K, Asada Y
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Journal Title
J Gerontol A Biol Sci Med Sci
Volume: 65-5
Pages: 547-52
Related Report
Peer Reviewed
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[Journal Article] Pericardial fat inflammation correlates with coronary artery disease2010
Author(s)
Konishi M, Sugiyama S, Sato Y, Oshima S, Sugamura K, Nozaki T, Ohba K, Matsubara J, Sumida H, Nagayoshi Y, Sakamoto K, Utsunomiya D, Awai K, Jinnouchi H, Matsuzawa Y, Yamashita Y, Asada Y, Kimura K, Umemura S, Ogawa H
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Journal Title
Atherosclerosis
Volume: 213-2
Pages: 649-55
Related Report
Peer Reviewed
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[Presentation] 臍帯動脈血栓症の一例2010
Author(s)
佐藤勇一郎、山田直志、木許恭宏、中原彰彦
Organizer
第30回日本小児病理研究会
Place of Presentation
大阪市
Year and Date
2010-09-04
Related Report
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