Significance of microRNA in T-cell malignancies

• Project/Area Number: 21590377
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Human pathology
• Research Institution: Nagoya City University
• Principal Investigator: INAGAKI Hiroshi 名古屋市立大学, 大学院・医学研究科, 教授 (30232507)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 成人T細胞性白血病 / マイクロRNA / 臨床病理学 / 遺伝子異常 / T細胞 / 機能解析 / 血液腫瘍

Research Abstract

Using microRNA array and quantitative PCR for some cell lines, we screened six microRNAs that may be important in adult T-cell leukemia/lymphoma(ATLL). Clinicopathological analysis of these six microRNAs showed that overexpression of one of these microRNAs(microRNA-X) was significantly associated with worse prognosis of the ATLL patients. Downregulation of microRNA-X by siRNA was associated with suppressed growth of the tumor cells of an ATLL cell line. These findings suggest that microRNA-X may play an important role in ATLL.

Research Products

• [Journal Article] Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis : a study of the Osaka Lymphoma Study Group (2012)
  • Author(s): Wada N, Zaki MA, Kohara M, Ogawa H, Sugiyama H, Nomura S, Matsumura I, Hino M, Kanakura Y, Inagaki H, Morii E, Aozasa K
  • Journal Title: Histopathology Volume: (in press)
• [Journal Article] Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma (2012)
  • Author(s): Nishikawa H, Maeda Y, Ishida T, Gnjatic S, Sato E, Mori F, Sugiyama D, Ito A, Fukumori Y, Utsunomiya A, Inagaki H, Old LJ, Ueda R, Sakaguchi S
  • Journal Title: Blood Volume: 119 Pages: 3097-104
• [Journal Article] Defucosylated anti-CCR4 monoclonal antibody(KW-0761) for relapsed adult T-cell leukemia-lymphoma : A multicenter phase II study (2012)
  • Author(s): Ishida T, Joh T, Uike N, Yamamoto K, Utsunomiya A, Yoshida S, Saburi Y, Miyamoto T, Takemoto S, Suzushima H, Tsukasaki K, Nosaka K, Fujiwara H, Ishitsuka K, Inagaki H, Ogura M, Akinaga S, Tomonaga M, Tobinai K, Ueda R
  • Journal Title: J Clin Oncol Volume: 30 Pages: 837-42
• [Journal Article] Characterization of chromosomal aberrations in thymic MALT lymphoma (2012)
  • Author(s): Kominato S, Nakayama T, Sato F, Yamada S, Xia H, Fujiyoshi Y, Hattori H, Inagaki H
  • Journal Title: Pathol Int Volume: 62 Pages: 93-8
  • NAID: 10031185173
• [Journal Article] Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma : A Multicenter Phase II Study (2012)
  • Author(s): Ishida T, Inagaki H, et al
  • Journal Title: J Clin Oncol Volume: 30 Pages: 837-842
  • Peer Reviewed
• [Journal Article] Characterization of chromosomal aberrations in thymic MALT lymphoma (2012)
  • Author(s): Kominato S, Inagaki H, et al
  • Journal Title: Pathol Int Volume: 62 Pages: 93-98
  • NAID: 10031185173
  • Peer Reviewed
• [Journal Article] The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma (2011)
  • Author(s): Ebi M, Kataoka H, Shimura T, Hirata Y, Mizushima T, Mizoshita T, Tanaka M, Tsukamoto H, Ozeki K, Tanida S, Kamiya T, Inagaki H, Joh T
  • Journal Title: Mol Med Report Volume: 4 Pages: 1151-51
• [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome (2011)
  • Author(s): Kojima M, Nakamura N, Nakazato Y, Igarashi T, Masawa N, Inagaki H
  • Journal Title: Leuk Lymphoma Volume: 52 Pages: 1150-2
• [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphoma (2011)
  • Author(s): Xia H, Nakayama T, Sakuma H, Yamada S, Sato F, Takino H, Okabe M, Fujiyoshi Y, Hattori H, Inagaki H
  • Journal Title: Hum Pathol Volume: 42 Pages: 1297-304
• [Journal Article] The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma (2011)
  • Author(s): Ebi M, Inagaki H, et al
  • Journal Title: Mol Med Report Volume: 4 Pages: 1151-1155
  • Peer Reviewed
• [Journal Article] Impact of CRTC 1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma (2011)
  • Author(s): Okumura Y, Inagaki H, et al
  • Journal Title: Histopathology Volume: 59 Pages: 90-97
  • Peer Reviewed
• [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome (2011)
  • Author(s): Kojima M, Inagaki H, et al
  • Journal Title: Leuk Lymphoma Volume: 52 Pages: 1150-1152
  • Peer Reviewed
• [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphoma (2011)
  • Author(s): Xia H, Inagaki H, et al
  • Journal Title: Hum Pathol Volume: 42 Pages: 1297-1304
  • Peer Reviewed
• [Journal Article] An aspiration material preparation system : application of a new liquid-based cytology technique for fine-needle aspiration of the breast (2011)
  • Author(s): Sakakibara E, Inagaki H, et al
  • Journal Title: Acta Cytol Volume: 55 Pages: 92-99
  • Peer Reviewed
• [Journal Article] 胃MALTリンパ腫とHelicobacter pylori感染 (2011)
  • Author(s): 稲垣宏, 他
  • Journal Title: 血液内科 Volume: 29 Pages: 535-542
• [Journal Article] 染色体・遺伝子転座-悪性リンパ腫・多発性骨髄腫病理診断に役立つ分子生物学(解説編) (2011)
  • Author(s): 稲垣宏, 他
  • Journal Title: 病理と臨床 Volume: 29 Pages: 468-471
• [Journal Article] 染色体・遺伝子転座-悪性リンパ腫・多発性骨髄腫病理診断に役立つ分子生物学(診断編) (2011)
  • Author(s): 稲垣宏, 他
  • Journal Title: 病理と臨床 Volume: 29 Pages: 472-476
• [Journal Article] Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma. (2011)
  • Author(s): Okumura Y, Inagaki H, et al.
  • Journal Title: Histopathology Volume: 59 Pages: 90-97
  • PMID: 21668476
  • Peer Reviewed
• [Journal Article] 染色体・遺伝子転座一悪性リンパ腫・多発性骨髄腫 病理診断に役立つ分子生物学(解説編) (2011)
  • Author(s): 稲垣宏、他
  • Journal Title: 病理と臨床 Volume: 29 Pages: 468-471
• [Journal Article] 染色体・遺伝子転座一悪性リンパ腫・多発性骨髄腫 病理診断に役立つ分子生物学(診断編) (2011)
  • Author(s): 稲垣宏、他
  • Journal Title: 病理と臨床 Volume: 29 Pages: 472-476
• [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis (2010)
  • Author(s): Sakuma H, Okumura F, Miyabe S, Sugiura M, Joh T, Shimozato K, Inagaki H
  • Journal Title: Scand J Immunol Volume: 72 Pages: 44-9
• [Journal Article] A complement-dependent, cytotoxicityenhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2Rγ(null) mouse lymphoma model (2010)
  • Author(s): Sato F, Ito A, Ishida T, Mori F, Takino H, Inagaki A, Ri M, Kusumoto S, Komatsu H, Iida S, Okada N, Inagaki H, Ueda R
  • Journal Title: Cancer Immunol Immunother Volume: 59 Pages: 1791-800
• [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called "plasma cell granuloma of the lung" (2010)
  • Author(s): Kojima M, Nakamura N, Itoh H, Kamiyoshihara M, Matsumoto M, Nakazato N, Fujisawa T, Motoori T, Masawa N, Inagaki H
  • Journal Title: Pathol Res Pract Volume: 206 Pages: 83-7
• [Journal Article] Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma (2010)
  • Author(s): Yamamoto K, Utsunomiya A, Tobinai K, Tsukasaki K, Uike N, Uozumi K, Yamaguchi K, Yamada Y, Hanada S, Tamura K, Nakamura S, Inagaki H, Ohshima K, Kiyoi H, Ishida T, Matsushima K, Akinaga S, Ogura M, Tomonaga M, Ueda R
  • Journal Title: J Clin Oncol Volume: 28 Pages: 1591-8
• [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called"plasma cell granuloma of the lung" (2010)
  • Author(s): Kojima M, Inagaki H, et al.
  • Journal Title: Pathol Res Pract Volume: 206 Pages: 83-87
  • Peer Reviewed
• [Journal Article] Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma. (2010)
  • Author(s): Yamamoto K, Inagaki H, et al.
  • Journal Title: J Clin Oncol Volume: 28 Pages: 1591-1598
  • Peer Reviewed
• [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis (2010)
  • Author(s): Sakuma H, Inagaki H, et al.
  • Journal Title: Scand J Immunol Volume: 72 Pages: 44-49
  • Peer Reviewed
• [Journal Article] A complement-dependent cytotoxicity-enhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2R-γ(null) mouse lymphoma model (2010)
  • Author(s): Sato F, Inagaki H, et al.
  • Journal Title: Cancer Immunol Immunother Volume: 59 Pages: 1791-1800
  • Peer Reviewed
• [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome (2010)
  • Author(s): Kojima M, Inagaki H, et al.
  • Journal Title: Leuk Lymphoma Volume: 28 Pages: 1591-1598
  • Peer Reviewed
• [Journal Article] 病理形態学キーワード第4章縦隔7 胸腺リンパ上皮病変 (2010)
  • Author(s): 稲垣宏
  • Journal Title: 病理と臨床 臨時増刊号 Volume: 28 Pages: 76-77
• [Journal Article] 節外性粘膜関連リンパ組織型辺縁帯リンパ腫(MALTリンパ腫) (2010)
  • Author(s): 稲垣宏, 山田勢至, 滝野寿
  • Journal Title: 病理と臨床 Volume: 28 Pages: 731-735
• [Journal Article] 比較腫瘍学 造血系腫瘍:造血器腫瘍の病理学的概要 悪性リンパ腫を中心に (2010)
  • Author(s): 稲垣宏
  • Journal Title: アニテックス Volume: 22 Pages: 4-8
• [Journal Article] 画像診断と病理 脾原発悪性リンパ腫 (2010)
  • Author(s): 荒川利直, 稲垣宏, 他
  • Journal Title: 画像診断 Volume: 30 Pages: 130-131
• [Journal Article] Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients with Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma (2010)
  • Author(s): Yamamoto K, Inagaki H, et al.
  • Journal Title: J Clin Oncol 28 Pages: 1591-8
  • Peer Reviewed
• [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis (2010)
  • Author(s): Sakuma H, Inagaki H, et al
  • Journal Title: Scand J Immunol (In press)
  • Peer Reviewed
• [Journal Article] Cyclin D1 protein overexpression in extramedullary plasmacytoma : A clinicopathologic study of 11 cases (2009)
  • Author(s): Kojima M, Motoori T, Tamaki Y, Igarashi T, Matsumoto M, Shimizu K, Ogawa A, Itoh H, Asano S, Masawa N, Inagaki H
  • Journal Title: J Clin Exp Hemato Volume: 49 Pages: 53-6
  • NAID: 10025683712
• [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model (2009)
  • Author(s): Ito A, Ishida T, Yano H, Inagaki A, Suzuki S, Sato F, Takino H, Mori F, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R
  • Journal Title: Cancer Immunol Immunother Volume: 58 Pages: 1195-206
• [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo (2009)
  • Author(s): Ito A, Ishida T, Utsunomiya A, Sato F, Mori F, Yano H, Inagaki A, Suzuki S, Takino H, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R
  • Journal Title: J Immunol Volume: 183 Pages: 4782-91
• [Journal Article] B-cell lymphoma associated with Sjogren's syndrome among Japanese patients : a clinicopathologic and immunohistochemical study of 15 cases (2009)
  • Author(s): Kojima M, Tsukamoto N, Yokohama A, Suzuki Y, Shimizu K, Nishikawa M, Murayama K, Miyanaga T, Isoda A, Shimizu K, Itoh H, Masawa N, Yoshida K, Inagaki H
  • Journal Title: J Clin Exp Hemato Volume: 49 Pages: 89-95
  • NAID: 10026387641
• [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rγ null mouse model (2009)
  • Author(s): Ito A, Inagaki H, et al.
  • Journal Title: Cancer Immunol Immunother 58 Pages: 1195-206
  • Peer Reviewed
• [Journal Article] Cyclin D1 protein overexpression in extramedullary plasmacytoma : A clinicopathologic study of 11 cases (2009)
  • Author(s): Kojima M, Inagaki H, et al.
  • Journal Title: J Clin Exp Hematopathol 49 Pages: 53-6
  • NAID: 10025683712
  • Peer Reviewed
• [Journal Article] Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in muco-epidermoid carcinoma : a molecular and clinicopathologic study of 101 cases (2009)
  • Author(s): Miyabe S, Inagaki H, et al.
  • Journal Title: J Oral Maxillofac Surg 67 Pages: 1432-41
  • Peer Reviewed
• [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid IL-2Rγ null mice in vivo (2009)
  • Author(s): Ito A, Inagaki H, et al.
  • Journal Title: J Immunol 183 Pages: 4782-91
  • Peer Reviewed
• [Journal Article] Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma (2009)
  • Author(s): Nakayama T, Inagaki H, et al.
  • Journal Title: Mod Pathol 22 Pages: 1575-81
  • Peer Reviewed
• [Journal Article] B-cell lymphoma associated with Sjogren's syndrome among Japanese patients : a clinicopathologic and immunohistochemical study of 15 cases (2009)
  • Author(s): Kojima M, Inagaki H, et al.
  • Journal Title: J Clin Exp Hematopathol 49 Pages: 89-95
  • NAID: 10026387641
  • Peer Reviewed
• [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called "plasma cell granuloma of the lung" (2009)
  • Author(s): Kojima M, Inagaki H, et al.
  • Journal Title: Pathol Res Pract 206 Pages: 83-7
  • Peer Reviewed
• [Journal Article] Prognostic significance of p27Kipl, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma : a molecular and clinicopathologic study of 101 cases. (2009)
  • Author(s): Miyabe S, Inagaki H, et al.
  • Journal Title: J Oral Maxillofac Surg Volume: 67 Pages: 1432-1441
  • PMID: 19531414
  • Peer Reviewed
• [Journal Article] Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma (2009)
  • Author(s): Nakayama T, Inagaki H, et al.
  • Journal Title: Mod Pathol Volume: 22 Pages: 1575-1581
  • PMID: 19749740
  • Peer Reviewed
• [Journal Article] 臨床検査の分子生物学 染色体検査(FISH法など) (2009)
  • Author(s): 滝野寿、稲垣宏、他
  • Journal Title: 分子消化器病 Volume: 6 Pages: 64-68
• [Journal Article] 胸腺MALTリンパ腫 (2009)
  • Author(s): 稲垣宏、他
  • Journal Title: 現代医学 Volume: 57 Pages: 53-58
  • NAID: 40016892995
• [Journal Article] Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model
  • Author(s): Mori F, Ishida T, Ito A, Sato F, Masaki A, Takino H, Ri M, Kusumoto S, Komatsu H, Ueda R, Inagaki H, Iida S
  • Journal Title: Blood Cancer Journal Volume: (In press)
• [Journal Article] FOXP1 overexpression and its clinicopathological significance in peripheral T-cell lymphoma, not otherwise specified
  • Author(s): Yamada S, Sato F, Xia H, Takino H, Kominato S, Ri M, Ishida T, Iida S, Inagaki H, Yamada K
  • Journal Title: Hum Pathol Volume: (in press)
• [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in type 1 autoimmune pancreatitis
  • Author(s): Okumura F, Sakuma H, Nakazawa T, Hayashi K, Naitoh I, Miyabe K, Yoshida M, Yamashita H, Ohara H, Inagaki H, Joh T
  • Journal Title: Pathol Int Volume: (in press)
  • NAID: 10031185207
• [Journal Article] FOXP1 Overexpression and Its Clinicopathological Significance in Peripheral T-cell Lymphoma, NOS
  • Author(s): Yamada S, Inagaki H, et al
  • Journal Title: Hum Pathol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma
  • Author(s): Nishikawa H, Inagaki H, et al
  • Journal Title: Blood Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis : a study of the Osaka Lymphoma Study Group
  • Author(s): Wada N, Inagaki H, et al
  • Journal Title: Histopathology Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Analysis of VH gene rerrangement and somatic hypermutation in type 1 autoimmune pancreatitis
  • Author(s): Okumura F, Inagaki H, et al
  • Journal Title: Pathol Int Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model
  • Author(s): Mori F, Inagaki H, et al
  • Journal Title: Blood Cancer J Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Impact of CRTC1/3-MAML2 Fusions on Histological Classification and Prognosis of Mucoepidermoid Carcinoma
  • Author(s): Okumura H, Inagaki H, et al.
  • Journal Title: Histopathology Volume: (In press)
  • Peer Reviewed
• [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary MALT lymphoma
  • Author(s): Xia H, Inagaki H, et al.
  • Journal Title: Hum Pathol Volume: (In press)
  • Peer Reviewed
• [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in type lautoimmune pancreatitis
  • Author(s): Okumura F, Inagaki H, et al.
  • Journal Title: Pathol Int
  • PMID: 22524659
  • Description: 印刷中
  • Peer Reviewed
• [Presentation] Clinicopathological Significance of MAML2 Split in Mucoepidermoid Carcinoma (2012)
  • Author(s): Inagaki H
  • Organizer: Workshop on Salivary Gland Tumor Research
  • Place of Presentation: Bethesda North Marriott Hotel, Bethesda MD, USA
  • Year and Date: 2012-02-06 – 2012-02-07
  • Invited
• [Presentation] Clinicopathological Significance of MAML2 Split in Mucoepidermoid Carcinoma (2012)
  • Author(s): Inagaki H
  • Organizer: Workshop on Salivary Gland Tumor Research
  • Place of Presentation: Bethesda North Marriott Hotel, Bethesda MD, USA(招待講演)
• [Presentation] ”非典型ワルチン腫瘍”におけるCRTC1/3-MAML2キメラ遺伝子の検討 (2011)
  • Author(s): 中山嵩久、稲垣宏、他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
  • Year and Date: 2011-04-26 – 2011-04-28
• [Presentation] Bevacizumab-induced potent antiyumor effect in a microenvironment-dependent mouse lymphoma model (2011)
  • Author(s): Mori F, Inagaki H, et al
  • Organizer: 第73回日本血液学会学術集会
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] Late relapse more than 5 years following limited-stage extranodal NK/T cell lymphoma, nasal type (2011)
  • Author(s): Totani H, Inagaki H, et al
  • Organizer: 第73回日本血液学会学術集会
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] Establishment of an angioimmunoblastic T-cell lymphoma(AITL) model in the NOG mounse (2011)
  • Author(s): Ito A, Inagaki H, et al
  • Organizer: 第73回日本血液学会
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] Potent Tax-specific CTL response to primay autologous ATL cells (2011)
  • Author(s): Suzuki S, Inagaki H, et al
  • Organizer: 第73回日本血液学会学術集会
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] Differential effect of thalidomide in the treatment of POEMS syndrome : Two case reports (2011)
  • Author(s): Yoshida T, Inagaki H, et al
  • Organizer: 第73回日本血液学会学術集会
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] 自己免疫性膵炎の免疫グロブリン遺伝子解析 (2011)
  • Author(s): 佐久間英規、稲垣宏、他
  • Organizer: 第51回日本リンパ網内系学会総会
  • Place of Presentation: 福岡国際会議場(福岡)
• [Presentation] NOGマウスによるT細胞性リンパ腫の病態解明 (2011)
  • Author(s): 伊藤旭, 稲垣宏, 他
  • Organizer: 第51回日本リンパ網内系学会シンポジウム(招待講演)
  • Place of Presentation: 福岡国際会議場(福岡)
• [Presentation] シェーグレン症候群およびIgG4関連慢性硬化性唾液腺炎における免疫グログリン重鎖遺伝子解析 (2011)
  • Author(s): 佐久間英規、稲垣宏、他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 非特定末梢型T細胞リンパ腫におけるFOXP1遺伝子発現の臨床病理学的意義 (2011)
  • Author(s): 山田勢至、稲垣宏、他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] NOGマウスリンパ腫モデルに対してCDC増強抗CD20抗体の抗腫瘍活性の検討 (2011)
  • Author(s): 佐藤文彦、稲垣宏、他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 成人T細胞白血病・リンパ腫におけるマイクロRNA発現異常の解析 (2011)
  • Author(s): 夏洪晶、稲垣宏、他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] NOGマウスによるT細胞性リンパ腫の病態解明 (2011)
  • Author(s): 伊藤旭, 稲垣宏, 他
  • Organizer: 第51回日本リンパ網内系学会シンポジウム
  • Place of Presentation: 福岡国際会議場(福岡)(招待講演)
• [Presentation] NOGマウスモデルによるT細胞性リンパ腫の病態解明 (2011)
  • Author(s): 佐久間英規、稲垣宏, 他
  • Organizer: 第51回日本リンパ網内系学会総会
  • Place of Presentation: 福岡国際会議場(福岡)
• [Presentation] Establishment of an angioimmunoblastic T-cell lymphoma (AITL) model in the NOG mounse (2011)
  • Author(s): Ito A, Inagaki H, et al
  • Organizer: 第73回日本血液学会プレナリー発表
  • Place of Presentation: 名古屋国際会議場(愛知)
• [Presentation] 唾液腺原発粘表皮癌119例における遺伝子メチル化についての分子病理学的検討 (2011)
  • Author(s): 宮部悟、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] NOGマウスリンパ腫モデルに対してCDC増強抗CD20抗体の抗腫瘍活性の検討 (2011)
  • Author(s): 佐藤文彦、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川
• [Presentation] 後縦隔嚢胞におけるPAX2の免疫組織化学検討 (2011)
  • Author(s): 服部日出雄、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 非ホルマリン系組織固定液の有用性に関する検討 (2011)
  • Author(s): 榊原健夫、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] CRTC1/3-MAML2キメラ遺伝子が粘表皮癌の病理学的分類や予後に与える影響 (2011)
  • Author(s): 奥村嘉英、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] "非典型ワルチン腫瘍"におけるCRTC1/3-MAML2キメラ遺伝子の検討 (2011)
  • Author(s): 中山嵩久、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 唾液腺原発粘表皮癌におけるFISH法を用いたキメラ遺伝子の検討 (2011)
  • Author(s): 野田晴菜、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 大腸印環細胞癌の亜型分類のこころみ (2011)
  • Author(s): 藤吉行雄、稲垣宏, 他
  • Organizer: 第100回日本病理学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 唾液腺原発粘表皮癌におけるCRTC3-MAML2キメラ遺伝子の臨床病理学的意義 (2010)
  • Author(s): 中山崇久, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-04-27 – 2010-04-29
• [Presentation] 粘表皮癌におけるCRTC1-MAML2、CRCT3-MAML2キメラ遺伝子の臨床病理学的意義 (2010)
  • Author(s): 奥村嘉英, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-04-27 – 2010-04-29
• [Presentation] 非ホルマリン系組織固定液の有用性に関する検討 (2010)
  • Author(s): 榊原健夫, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-04-27 – 2010-04-29
• [Presentation] Oncocytomaと鑑別が困難であった腎臓のPapillary renal cell carcinomaの一例 (2010)
  • Author(s): 藤吉行雄, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-04-27 – 2010-04-29
• [Presentation] 膿胸関連肉腫の1症例 (2010)
  • Author(s): 服部日出雄, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-04-27 – 2010-04-29
• [Presentation] A CDC-enhancing anti-CD20 mAb mediating potent antitumor activity in the humanized NOG mouse model (2010)
  • Author(s): Ito A, Inagaki H, et al
  • Organizer: 第72回日本血液学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 肺MALTリンパ腫における遺伝子異常とIgH遺伝子体細胞変異 (2010)
  • Author(s): 夏洪晶, 稲垣宏, 他
  • Organizer: 第50回日本リンパ網内系学会総会
  • Place of Presentation: 新潟コンベンションセンター(新潟)
• [Presentation] 縦隔・胸腺のリンパ増殖性疾患の診断シンポジウム2縦隔腫瘍の多様性はどこまでわかってきたか (2010)
  • Author(s): 稲垣宏
  • Organizer: 第99回日本病理学会総会(招待講演)
  • Place of Presentation: 京王プラザホテル(東京)
• [Presentation] 縦隔・胸腺のリンパ増殖性疾患の診断シンポジウム2縦隔腫瘍の多様性はどこまでわかってきたか (2010)
  • Author(s): 稲垣宏
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] 唾液腺原発粘表皮癌におけるCRTC3-MAML2キメラ遺伝子の臨床病理学的意義 (2010)
  • Author(s): 中山崇久, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] 粘表皮癌におけるCRTCI-MAMI2、CRCT3-MAML2キメラ遺伝子の臨床病理学的意義 (2010)
  • Author(s): 奥村嘉英, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] 非ホルマリン系組織固定液の有用性に関する検討 (2010)
  • Author(s): 榊原健夫, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] Oncocytomaと鑑別が困難であった腎臓のpapillary renal cell carcinomaの一例 (2010)
  • Author(s): 藤吉行雄, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] 膿胸関連肉腫の1症例 (2010)
  • Author(s): 服部日出雄, 稲垣宏, 他
  • Organizer: 第99回日本病理学会総会
  • Place of Presentation: 東京(京王プラザホテル)
• [Presentation] 肺MALT リンパ腫における遺伝子異常とIgH 遺伝子体細胞変異 (2010)
  • Author(s): 夏洪晶, 稲垣宏, 他
  • Organizer: 第50回日本リンパ網内系学会総会
  • Place of Presentation: 新潟(新潟コンベンションセンター)
• [Presentation] A CDC-enhancing anti-CD20 mAb mediating potent antitumor activity in the humanized NOG mouse model (2010)
  • Author(s): Ito A, Inagaki H, et al.
  • Organizer: 第72回日本血液学会総会
  • Place of Presentation: 横浜(パシフィコ横浜)
• [Presentation] サルコイドーシスに合併した腹部大動脈破裂の1部検例 (2009)
  • Author(s): 小湊知、稲垣宏、他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都国際会議場(京都)
  • Year and Date: 2009-05-01 – 2009-05-03
• [Presentation] 腎静脈発生と考えられた腎平滑筋肉腫の1例 (2009)
  • Author(s): 中山崇久、稲垣宏、他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都国際会議場(京都)
  • Year and Date: 2009-05-01 – 2009-05-03
• [Presentation] 小児こう胞性疾患の免疫染色的検討 (2009)
  • Author(s): 清水重喜、稲垣宏、他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都国際会議場(京都)
  • Year and Date: 2009-05-01 – 2009-05-03
• [Presentation] 造血系腫瘍の病理学的概要 (2009)
  • Author(s): 稲垣宏
  • Organizer: 第3回伴侶動物の臨床医学研究会(招待講演)
  • Place of Presentation: 岡崎コンファレンスセンター(愛知)
• [Presentation] 悪性リンパ腫:病理診断と治療 (2009)
  • Author(s): 稲垣宏
  • Organizer: 第48回中部医学検査学会(招待講演)
  • Place of Presentation: 三島市民文化会館(静岡)
• [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立 (2009)
  • Author(s): 伊藤旭、稲垣宏、他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都国際会議場(京都)
• [Presentation] EBER陽性のALK陰性anaplastic large cell lymphoma(ALCL)の2例 (2009)
  • Author(s): 稲垣淳、稲垣宏、他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都国際会議場(京都)
• [Presentation] B-LBLモデルマウスの樹立及び病態解析 (2009)
  • Author(s): 森芙美子、稲垣宏、他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都国際会議場(京都)
• [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立 (2009)
  • Author(s): 伊藤旭、稲垣宏、他
  • Organizer: 第68回日本癌学会総会
  • Place of Presentation: パシフィコ横浜(神奈川)
• [Presentation] 胸腺MALTリンパ腫における遺伝子過剰メチル化とFas遺伝子異常の解析 (2009)
  • Author(s): 滝野寿、稲垣宏、他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都国際会議場(京都)
• [Presentation] サルコイドーシスに合併した腹部大動脈破裂の1剖検例 (2009)
  • Author(s): 小湊知, 稲垣宏, 他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都
• [Presentation] 胸腺MALTリンパ腫における遺伝子過剰メチル化とFas遺伝子異常の解析 (2009)
  • Author(s): 滝野寿, 稲垣宏, 他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都
• [Presentation] 腎静脈発生と考えられた腎平滑筋肉腫の1例 (2009)
  • Author(s): 中山崇久, 稲垣宏, 他
  • Organizer: 第98回日本病理学会総会
  • Place of Presentation: 京都
• [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立 (2009)
  • Author(s): 伊藤旭, 稲垣宏, 他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] EBER陽性のALK陰性 anaplastic large cell lymphoma(ALCL)の2例 (2009)
  • Author(s): 稲垣淳, 稲垣宏, 他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] B-LBLモデルマウスの樹立及び病態解析 (2009)
  • Author(s): 森芙美子, 稲垣宏, 他
  • Organizer: 第71回日本血液学会総会
  • Place of Presentation: 京都
• [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立 (2009)
  • Author(s): 伊藤旭, 稲垣宏, 他
  • Organizer: 第68回日本癌学会総会
  • Place of Presentation: 横浜
• [Presentation] 悪性リンパ腫:病理診断と治療 (2009)
  • Author(s): 稲垣宏
  • Organizer: 第48回中部医学検査学会
  • Place of Presentation: 三島
• [Presentation] 造血系腫瘍の病理学的概要 (2009)
  • Author(s): 稲垣宏
  • Organizer: 第三回伴侶動物の臨床医学研究会
  • Place of Presentation: 岡崎
• [Book] 癌診療指針のための病理診断プラクティス:食道癌・胃癌 (2012)
  • Author(s): 稲垣宏, 楠本茂, 片岡洋望
  • Total Pages: 307
  • Publisher: 中山書店
• [Book] 癌診療指針のための病理診断プラクティス:リンパ球増殖疾患 (2010)
  • Author(s): 稲垣宏, 楠本茂
  • Total Pages: 335
  • Publisher: 中山書店
• [Book] WHO血液腫瘍分類WHO分類2008をうまく活用するために (2010)
  • Author(s): 佐藤文彦、稲垣宏
  • Total Pages: 587
  • Publisher: 医薬ジャーナル社
• [Book] 癌診療指針のための病理診断プラクティス (2010)
  • Author(s): 稲垣宏, 楠本茂
  • Total Pages: 335
  • Publisher: 中山書店
• [Book] WHO血液腫瘍分類:WHO分類2008をうまく活用するために (2010)
  • Author(s): 佐藤文彦, 稲垣宏
  • Total Pages: 587
  • Publisher: 医薬ジャーナル社
• [Book] WHO血液腫瘍分類 WHO分類2008をうまく活用するために (2010)
  • Author(s): 佐藤文彦, 稲垣宏
  • Total Pages: 587
  • Publisher: 医薬ジャーナル社
• [Remarks]
  • URL: http://www.med.nagoya-cu.ac.jp/patho2.dir/4pep.html
• [Remarks]
  • URL: http://www.med.nagoya-cu.ac.jp/patho2.dir/4pep.html
• [Remarks]
  • URL: http://www.med.nagoya-cu.ac.jp/patho2.dir/index.htm
• [Remarks]
  • URL: http://www.med.nagoya-cu.ac.jp/patho2.dir/index.htm