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Significance of microRNA in T-cell malignancies

Research Project

Project/Area Number 21590377
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Human pathology
Research InstitutionNagoya City University

Principal Investigator

INAGAKI Hiroshi  名古屋市立大学, 大学院・医学研究科, 教授 (30232507)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords成人T細胞性白血病 / マイクロRNA / 臨床病理学 / 遺伝子異常 / T細胞 / 機能解析 / 血液腫瘍
Research Abstract

Using microRNA array and quantitative PCR for some cell lines, we screened six microRNAs that may be important in adult T-cell leukemia/lymphoma(ATLL). Clinicopathological analysis of these six microRNAs showed that overexpression of one of these microRNAs(microRNA-X) was significantly associated with worse prognosis of the ATLL patients. Downregulation of microRNA-X by siRNA was associated with suppressed growth of the tumor cells of an ATLL cell line. These findings suggest that microRNA-X may play an important role in ATLL.

Report

(5 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Products Report
  • Research Products

    (131 results)

All 2012 2011 2010 2009 Other

All Journal Article (61 results) (of which Peer Reviewed: 32 results) Presentation (60 results) (of which Invited: 1 results) Book (6 results) Remarks (4 results)

  • [Journal Article] Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis : a study of the Osaka Lymphoma Study Group2012

    • Author(s)
      Wada N, Zaki MA, Kohara M, Ogawa H, Sugiyama H, Nomura S, Matsumura I, Hino M, Kanakura Y, Inagaki H, Morii E, Aozasa K
    • Journal Title

      Histopathology

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma2012

    • Author(s)
      Nishikawa H, Maeda Y, Ishida T, Gnjatic S, Sato E, Mori F, Sugiyama D, Ito A, Fukumori Y, Utsunomiya A, Inagaki H, Old LJ, Ueda R, Sakaguchi S
    • Journal Title

      Blood

      Volume: 119 Pages: 3097-104

    • Related Report
      2011 Final Research Report
  • [Journal Article] Defucosylated anti-CCR4 monoclonal antibody(KW-0761) for relapsed adult T-cell leukemia-lymphoma : A multicenter phase II study2012

    • Author(s)
      Ishida T, Joh T, Uike N, Yamamoto K, Utsunomiya A, Yoshida S, Saburi Y, Miyamoto T, Takemoto S, Suzushima H, Tsukasaki K, Nosaka K, Fujiwara H, Ishitsuka K, Inagaki H, Ogura M, Akinaga S, Tomonaga M, Tobinai K, Ueda R
    • Journal Title

      J Clin Oncol

      Volume: 30 Pages: 837-42

    • Related Report
      2011 Final Research Report
  • [Journal Article] Characterization of chromosomal aberrations in thymic MALT lymphoma2012

    • Author(s)
      Kominato S, Nakayama T, Sato F, Yamada S, Xia H, Fujiyoshi Y, Hattori H, Inagaki H
    • Journal Title

      Pathol Int

      Volume: 62 Pages: 93-8

    • NAID

      10031185173

    • Related Report
      2011 Final Research Report
  • [Journal Article] Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma : A Multicenter Phase II Study2012

    • Author(s)
      Ishida T, Inagaki H, et al
    • Journal Title

      J Clin Oncol

      Volume: 30 Pages: 837-842

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of chromosomal aberrations in thymic MALT lymphoma2012

    • Author(s)
      Kominato S, Inagaki H, et al
    • Journal Title

      Pathol Int

      Volume: 62 Pages: 93-98

    • NAID

      10031185173

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma2011

    • Author(s)
      Ebi M, Kataoka H, Shimura T, Hirata Y, Mizushima T, Mizoshita T, Tanaka M, Tsukamoto H, Ozeki K, Tanida S, Kamiya T, Inagaki H, Joh T
    • Journal Title

      Mol Med Report

      Volume: 4 Pages: 1151-51

    • Related Report
      2011 Final Research Report
  • [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome2011

    • Author(s)
      Kojima M, Nakamura N, Nakazato Y, Igarashi T, Masawa N, Inagaki H
    • Journal Title

      Leuk Lymphoma

      Volume: 52 Pages: 1150-2

    • Related Report
      2011 Final Research Report
  • [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphoma2011

    • Author(s)
      Xia H, Nakayama T, Sakuma H, Yamada S, Sato F, Takino H, Okabe M, Fujiyoshi Y, Hattori H, Inagaki H
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 1297-304

    • Related Report
      2011 Final Research Report
  • [Journal Article] The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma2011

    • Author(s)
      Ebi M, Inagaki H, et al
    • Journal Title

      Mol Med Report

      Volume: 4 Pages: 1151-1155

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of CRTC 1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma2011

    • Author(s)
      Okumura Y, Inagaki H, et al
    • Journal Title

      Histopathology

      Volume: 59 Pages: 90-97

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome2011

    • Author(s)
      Kojima M, Inagaki H, et al
    • Journal Title

      Leuk Lymphoma

      Volume: 52 Pages: 1150-1152

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary mucosa-associated lymphoid tissue lymphoma2011

    • Author(s)
      Xia H, Inagaki H, et al
    • Journal Title

      Hum Pathol

      Volume: 42 Pages: 1297-1304

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An aspiration material preparation system : application of a new liquid-based cytology technique for fine-needle aspiration of the breast2011

    • Author(s)
      Sakakibara E, Inagaki H, et al
    • Journal Title

      Acta Cytol

      Volume: 55 Pages: 92-99

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report Products Report
    • Peer Reviewed
  • [Journal Article] 胃MALTリンパ腫とHelicobacter pylori感染2011

    • Author(s)
      稲垣宏, 他
    • Journal Title

      血液内科

      Volume: 29 Pages: 535-542

    • Related Report
      2011 Annual Research Report Products Report
  • [Journal Article] 染色体・遺伝子転座-悪性リンパ腫・多発性骨髄腫病理診断に役立つ分子生物学(解説編)2011

    • Author(s)
      稲垣宏, 他
    • Journal Title

      病理と臨床

      Volume: 29 Pages: 468-471

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 染色体・遺伝子転座-悪性リンパ腫・多発性骨髄腫病理診断に役立つ分子生物学(診断編)2011

    • Author(s)
      稲垣宏, 他
    • Journal Title

      病理と臨床

      Volume: 29 Pages: 472-476

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma.2011

    • Author(s)
      Okumura Y, Inagaki H, et al.
    • Journal Title

      Histopathology

      Volume: 59 Pages: 90-97

    • PMID

      21668476

    • Related Report
      Products Report
    • Peer Reviewed
  • [Journal Article] 染色体・遺伝子転座一悪性リンパ腫・多発性骨髄腫 病理診断に役立つ分子生物学(解説編)2011

    • Author(s)
      稲垣宏、他
    • Journal Title

      病理と臨床

      Volume: 29 Pages: 468-471

    • Related Report
      Products Report
  • [Journal Article] 染色体・遺伝子転座一悪性リンパ腫・多発性骨髄腫 病理診断に役立つ分子生物学(診断編)2011

    • Author(s)
      稲垣宏、他
    • Journal Title

      病理と臨床

      Volume: 29 Pages: 472-476

    • Related Report
      Products Report
  • [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis2010

    • Author(s)
      Sakuma H, Okumura F, Miyabe S, Sugiura M, Joh T, Shimozato K, Inagaki H
    • Journal Title

      Scand J Immunol

      Volume: 72 Pages: 44-9

    • Related Report
      2011 Final Research Report
  • [Journal Article] A complement-dependent, cytotoxicityenhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2Rγ(null) mouse lymphoma model2010

    • Author(s)
      Sato F, Ito A, Ishida T, Mori F, Takino H, Inagaki A, Ri M, Kusumoto S, Komatsu H, Iida S, Okada N, Inagaki H, Ueda R
    • Journal Title

      Cancer Immunol Immunother

      Volume: 59 Pages: 1791-800

    • Related Report
      2011 Final Research Report
  • [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called "plasma cell granuloma of the lung"2010

    • Author(s)
      Kojima M, Nakamura N, Itoh H, Kamiyoshihara M, Matsumoto M, Nakazato N, Fujisawa T, Motoori T, Masawa N, Inagaki H
    • Journal Title

      Pathol Res Pract

      Volume: 206 Pages: 83-7

    • Related Report
      2011 Final Research Report
  • [Journal Article] Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma2010

    • Author(s)
      Yamamoto K, Utsunomiya A, Tobinai K, Tsukasaki K, Uike N, Uozumi K, Yamaguchi K, Yamada Y, Hanada S, Tamura K, Nakamura S, Inagaki H, Ohshima K, Kiyoi H, Ishida T, Matsushima K, Akinaga S, Ogura M, Tomonaga M, Ueda R
    • Journal Title

      J Clin Oncol

      Volume: 28 Pages: 1591-8

    • Related Report
      2011 Final Research Report
  • [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called"plasma cell granuloma of the lung"2010

    • Author(s)
      Kojima M, Inagaki H, et al.
    • Journal Title

      Pathol Res Pract

      Volume: 206 Pages: 83-87

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma.2010

    • Author(s)
      Yamamoto K, Inagaki H, et al.
    • Journal Title

      J Clin Oncol

      Volume: 28 Pages: 1591-1598

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis2010

    • Author(s)
      Sakuma H, Inagaki H, et al.
    • Journal Title

      Scand J Immunol

      Volume: 72 Pages: 44-49

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A complement-dependent cytotoxicity-enhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2R-γ(null) mouse lymphoma model2010

    • Author(s)
      Sato F, Inagaki H, et al.
    • Journal Title

      Cancer Immunol Immunother

      Volume: 59 Pages: 1791-1800

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light-chain-restricted monocytoid B-cell cluster in reactive lymphadenitis associated with Sjogren syndrome2010

    • Author(s)
      Kojima M, Inagaki H, et al.
    • Journal Title

      Leuk Lymphoma

      Volume: 28 Pages: 1591-1598

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 病理形態学キーワード第4章縦隔7 胸腺リンパ上皮病変2010

    • Author(s)
      稲垣宏
    • Journal Title

      病理と臨床 臨時増刊号

      Volume: 28 Pages: 76-77

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 節外性粘膜関連リンパ組織型辺縁帯リンパ腫(MALTリンパ腫)2010

    • Author(s)
      稲垣宏, 山田勢至, 滝野寿
    • Journal Title

      病理と臨床

      Volume: 28 Pages: 731-735

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 比較腫瘍学 造血系腫瘍:造血器腫瘍の病理学的概要 悪性リンパ腫を中心に2010

    • Author(s)
      稲垣宏
    • Journal Title

      アニテックス

      Volume: 22 Pages: 4-8

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 画像診断と病理 脾原発悪性リンパ腫2010

    • Author(s)
      荒川利直, 稲垣宏, 他
    • Journal Title

      画像診断

      Volume: 30 Pages: 130-131

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients with Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma2010

    • Author(s)
      Yamamoto K, Inagaki H, et al.
    • Journal Title

      J Clin Oncol 28

      Pages: 1591-8

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis2010

    • Author(s)
      Sakuma H, Inagaki H, et al
    • Journal Title

      Scand J Immunol (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyclin D1 protein overexpression in extramedullary plasmacytoma : A clinicopathologic study of 11 cases2009

    • Author(s)
      Kojima M, Motoori T, Tamaki Y, Igarashi T, Matsumoto M, Shimizu K, Ogawa A, Itoh H, Asano S, Masawa N, Inagaki H
    • Journal Title

      J Clin Exp Hemato

      Volume: 49 Pages: 53-6

    • NAID

      10025683712

    • Related Report
      2011 Final Research Report
  • [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rgamma(null) mouse model2009

    • Author(s)
      Ito A, Ishida T, Yano H, Inagaki A, Suzuki S, Sato F, Takino H, Mori F, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R
    • Journal Title

      Cancer Immunol Immunother

      Volume: 58 Pages: 1195-206

    • Related Report
      2011 Final Research Report
  • [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid, IL-2R gamma(null) mice in vivo2009

    • Author(s)
      Ito A, Ishida T, Utsunomiya A, Sato F, Mori F, Yano H, Inagaki A, Suzuki S, Takino H, Ri M, Kusumoto S, Komatsu H, Iida S, Inagaki H, Ueda R
    • Journal Title

      J Immunol

      Volume: 183 Pages: 4782-91

    • Related Report
      2011 Final Research Report
  • [Journal Article] B-cell lymphoma associated with Sjogren's syndrome among Japanese patients : a clinicopathologic and immunohistochemical study of 15 cases2009

    • Author(s)
      Kojima M, Tsukamoto N, Yokohama A, Suzuki Y, Shimizu K, Nishikawa M, Murayama K, Miyanaga T, Isoda A, Shimizu K, Itoh H, Masawa N, Yoshida K, Inagaki H
    • Journal Title

      J Clin Exp Hemato

      Volume: 49 Pages: 89-95

    • NAID

      10026387641

    • Related Report
      2011 Final Research Report
  • [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rγ null mouse model2009

    • Author(s)
      Ito A, Inagaki H, et al.
    • Journal Title

      Cancer Immunol Immunother 58

      Pages: 1195-206

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cyclin D1 protein overexpression in extramedullary plasmacytoma : A clinicopathologic study of 11 cases2009

    • Author(s)
      Kojima M, Inagaki H, et al.
    • Journal Title

      J Clin Exp Hematopathol 49

      Pages: 53-6

    • NAID

      10025683712

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in muco-epidermoid carcinoma : a molecular and clinicopathologic study of 101 cases2009

    • Author(s)
      Miyabe S, Inagaki H, et al.
    • Journal Title

      J Oral Maxillofac Surg 67

      Pages: 1432-41

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Defucosylated anti-CCR4 monoclonal antibody exerts potent ADCC against primary ATLL cells mediated by autologous human immune cells in NOD/Shi-scid IL-2Rγ null mice in vivo2009

    • Author(s)
      Ito A, Inagaki H, et al.
    • Journal Title

      J Immunol 183

      Pages: 4782-91

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma2009

    • Author(s)
      Nakayama T, Inagaki H, et al.
    • Journal Title

      Mod Pathol 22

      Pages: 1575-81

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] B-cell lymphoma associated with Sjogren's syndrome among Japanese patients : a clinicopathologic and immunohistochemical study of 15 cases2009

    • Author(s)
      Kojima M, Inagaki H, et al.
    • Journal Title

      J Clin Exp Hematopathol 49

      Pages: 89-95

    • NAID

      10026387641

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Presence of immunoglobulin heavy chain rearrangement in so-called "plasma cell granuloma of the lung"2009

    • Author(s)
      Kojima M, Inagaki H, et al.
    • Journal Title

      Pathol Res Pract 206

      Pages: 83-7

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of p27Kipl, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma : a molecular and clinicopathologic study of 101 cases.2009

    • Author(s)
      Miyabe S, Inagaki H, et al.
    • Journal Title

      J Oral Maxillofac Surg

      Volume: 67 Pages: 1432-1441

    • PMID

      19531414

    • Related Report
      Products Report
    • Peer Reviewed
  • [Journal Article] Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma2009

    • Author(s)
      Nakayama T, Inagaki H, et al.
    • Journal Title

      Mod Pathol

      Volume: 22 Pages: 1575-1581

    • PMID

      19749740

    • Related Report
      Products Report
    • Peer Reviewed
  • [Journal Article] 臨床検査の分子生物学 染色体検査(FISH法など)2009

    • Author(s)
      滝野寿、稲垣宏、他
    • Journal Title

      分子消化器病

      Volume: 6 Pages: 64-68

    • Related Report
      Products Report
  • [Journal Article] 胸腺MALTリンパ腫2009

    • Author(s)
      稲垣宏、他
    • Journal Title

      現代医学

      Volume: 57 Pages: 53-58

    • NAID

      40016892995

    • Related Report
      Products Report
  • [Journal Article] Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model

    • Author(s)
      Mori F, Ishida T, Ito A, Sato F, Masaki A, Takino H, Ri M, Kusumoto S, Komatsu H, Ueda R, Inagaki H, Iida S
    • Journal Title

      Blood Cancer Journal

      Volume: (In press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] FOXP1 overexpression and its clinicopathological significance in peripheral T-cell lymphoma, not otherwise specified

    • Author(s)
      Yamada S, Sato F, Xia H, Takino H, Kominato S, Ri M, Ishida T, Iida S, Inagaki H, Yamada K
    • Journal Title

      Hum Pathol

      Volume: (in press)

    • Related Report
      2011 Final Research Report
  • [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in type 1 autoimmune pancreatitis

    • Author(s)
      Okumura F, Sakuma H, Nakazawa T, Hayashi K, Naitoh I, Miyabe K, Yoshida M, Yamashita H, Ohara H, Inagaki H, Joh T
    • Journal Title

      Pathol Int

      Volume: (in press)

    • NAID

      10031185207

    • Related Report
      2011 Final Research Report
  • [Journal Article] FOXP1 Overexpression and Its Clinicopathological Significance in Peripheral T-cell Lymphoma, NOS

    • Author(s)
      Yamada S, Inagaki H, et al
    • Journal Title

      Hum Pathol

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma

    • Author(s)
      Nishikawa H, Inagaki H, et al
    • Journal Title

      Blood

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis : a study of the Osaka Lymphoma Study Group

    • Author(s)
      Wada N, Inagaki H, et al
    • Journal Title

      Histopathology

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of VH gene rerrangement and somatic hypermutation in type 1 autoimmune pancreatitis

    • Author(s)
      Okumura F, Inagaki H, et al
    • Journal Title

      Pathol Int

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Potent antitumor effects of bevacizumab in a microenvironment-dependent human lymphoma mouse model

    • Author(s)
      Mori F, Inagaki H, et al
    • Journal Title

      Blood Cancer J

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of CRTC1/3-MAML2 Fusions on Histological Classification and Prognosis of Mucoepidermoid Carcinoma

    • Author(s)
      Okumura H, Inagaki H, et al.
    • Journal Title

      Histopathology

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of API2-MALT1 fusion, trisomies, and immunoglobulin VH genes in pulmonary MALT lymphoma

    • Author(s)
      Xia H, Inagaki H, et al.
    • Journal Title

      Hum Pathol

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of VH gene rearrangement and somatic hypermutation in type lautoimmune pancreatitis

    • Author(s)
      Okumura F, Inagaki H, et al.
    • Journal Title

      Pathol Int

    • PMID

      22524659

    • Description
      印刷中
    • Related Report
      Products Report
    • Peer Reviewed
  • [Presentation] Clinicopathological Significance of MAML2 Split in Mucoepidermoid Carcinoma2012

    • Author(s)
      Inagaki H
    • Organizer
      Workshop on Salivary Gland Tumor Research
    • Place of Presentation
      Bethesda North Marriott Hotel, Bethesda MD, USA
    • Year and Date
      2012-02-06 – 2012-02-07
    • Related Report
      Products Report
    • Invited
  • [Presentation] Clinicopathological Significance of MAML2 Split in Mucoepidermoid Carcinoma2012

    • Author(s)
      Inagaki H
    • Organizer
      Workshop on Salivary Gland Tumor Research
    • Place of Presentation
      Bethesda North Marriott Hotel, Bethesda MD, USA(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] ”非典型ワルチン腫瘍”におけるCRTC1/3-MAML2キメラ遺伝子の検討2011

    • Author(s)
      中山嵩久、稲垣宏、他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-04-26 – 2011-04-28
    • Related Report
      Products Report
  • [Presentation] Bevacizumab-induced potent antiyumor effect in a microenvironment-dependent mouse lymphoma model2011

    • Author(s)
      Mori F, Inagaki H, et al
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Late relapse more than 5 years following limited-stage extranodal NK/T cell lymphoma, nasal type2011

    • Author(s)
      Totani H, Inagaki H, et al
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Establishment of an angioimmunoblastic T-cell lymphoma(AITL) model in the NOG mounse2011

    • Author(s)
      Ito A, Inagaki H, et al
    • Organizer
      第73回日本血液学会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Final Research Report
  • [Presentation] Potent Tax-specific CTL response to primay autologous ATL cells2011

    • Author(s)
      Suzuki S, Inagaki H, et al
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Differential effect of thalidomide in the treatment of POEMS syndrome : Two case reports2011

    • Author(s)
      Yoshida T, Inagaki H, et al
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 自己免疫性膵炎の免疫グロブリン遺伝子解析2011

    • Author(s)
      佐久間英規、稲垣宏、他
    • Organizer
      第51回日本リンパ網内系学会総会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Related Report
      2011 Final Research Report
  • [Presentation] NOGマウスによるT細胞性リンパ腫の病態解明2011

    • Author(s)
      伊藤旭, 稲垣宏, 他
    • Organizer
      第51回日本リンパ網内系学会シンポジウム(招待講演)
    • Place of Presentation
      福岡国際会議場(福岡)
    • Related Report
      2011 Final Research Report
  • [Presentation] シェーグレン症候群およびIgG4関連慢性硬化性唾液腺炎における免疫グログリン重鎖遺伝子解析2011

    • Author(s)
      佐久間英規、稲垣宏、他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] 非特定末梢型T細胞リンパ腫におけるFOXP1遺伝子発現の臨床病理学的意義2011

    • Author(s)
      山田勢至、稲垣宏、他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] NOGマウスリンパ腫モデルに対してCDC増強抗CD20抗体の抗腫瘍活性の検討2011

    • Author(s)
      佐藤文彦、稲垣宏、他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Final Research Report
  • [Presentation] 成人T細胞白血病・リンパ腫におけるマイクロRNA発現異常の解析2011

    • Author(s)
      夏洪晶、稲垣宏、他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] NOGマウスによるT細胞性リンパ腫の病態解明2011

    • Author(s)
      伊藤旭, 稲垣宏, 他
    • Organizer
      第51回日本リンパ網内系学会シンポジウム
    • Place of Presentation
      福岡国際会議場(福岡)(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] NOGマウスモデルによるT細胞性リンパ腫の病態解明2011

    • Author(s)
      佐久間英規、稲垣宏, 他
    • Organizer
      第51回日本リンパ網内系学会総会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Establishment of an angioimmunoblastic T-cell lymphoma (AITL) model in the NOG mounse2011

    • Author(s)
      Ito A, Inagaki H, et al
    • Organizer
      第73回日本血液学会プレナリー発表
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 唾液腺原発粘表皮癌119例における遺伝子メチル化についての分子病理学的検討2011

    • Author(s)
      宮部悟、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] NOGマウスリンパ腫モデルに対してCDC増強抗CD20抗体の抗腫瘍活性の検討2011

    • Author(s)
      佐藤文彦、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川
    • Related Report
      2011 Annual Research Report
  • [Presentation] 後縦隔嚢胞におけるPAX2の免疫組織化学検討2011

    • Author(s)
      服部日出雄、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] 非ホルマリン系組織固定液の有用性に関する検討2011

    • Author(s)
      榊原健夫、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] CRTC1/3-MAML2キメラ遺伝子が粘表皮癌の病理学的分類や予後に与える影響2011

    • Author(s)
      奥村嘉英、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] "非典型ワルチン腫瘍"におけるCRTC1/3-MAML2キメラ遺伝子の検討2011

    • Author(s)
      中山嵩久、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 唾液腺原発粘表皮癌におけるFISH法を用いたキメラ遺伝子の検討2011

    • Author(s)
      野田晴菜、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] 大腸印環細胞癌の亜型分類のこころみ2011

    • Author(s)
      藤吉行雄、稲垣宏, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Annual Research Report Products Report
  • [Presentation] 唾液腺原発粘表皮癌におけるCRTC3-MAML2キメラ遺伝子の臨床病理学的意義2010

    • Author(s)
      中山崇久, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-04-27 – 2010-04-29
    • Related Report
      Products Report
  • [Presentation] 粘表皮癌におけるCRTC1-MAML2、CRCT3-MAML2キメラ遺伝子の臨床病理学的意義2010

    • Author(s)
      奥村嘉英, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-04-27 – 2010-04-29
    • Related Report
      Products Report
  • [Presentation] 非ホルマリン系組織固定液の有用性に関する検討2010

    • Author(s)
      榊原健夫, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-04-27 – 2010-04-29
    • Related Report
      Products Report
  • [Presentation] Oncocytomaと鑑別が困難であった腎臓のPapillary renal cell carcinomaの一例2010

    • Author(s)
      藤吉行雄, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-04-27 – 2010-04-29
    • Related Report
      Products Report
  • [Presentation] 膿胸関連肉腫の1症例2010

    • Author(s)
      服部日出雄, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-04-27 – 2010-04-29
    • Related Report
      Products Report
  • [Presentation] A CDC-enhancing anti-CD20 mAb mediating potent antitumor activity in the humanized NOG mouse model2010

    • Author(s)
      Ito A, Inagaki H, et al
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Final Research Report
  • [Presentation] 肺MALTリンパ腫における遺伝子異常とIgH遺伝子体細胞変異2010

    • Author(s)
      夏洪晶, 稲垣宏, 他
    • Organizer
      第50回日本リンパ網内系学会総会
    • Place of Presentation
      新潟コンベンションセンター(新潟)
    • Related Report
      2011 Final Research Report
  • [Presentation] 縦隔・胸腺のリンパ増殖性疾患の診断シンポジウム2縦隔腫瘍の多様性はどこまでわかってきたか2010

    • Author(s)
      稲垣宏
    • Organizer
      第99回日本病理学会総会(招待講演)
    • Place of Presentation
      京王プラザホテル(東京)
    • Related Report
      2011 Final Research Report
  • [Presentation] 縦隔・胸腺のリンパ増殖性疾患の診断シンポジウム2縦隔腫瘍の多様性はどこまでわかってきたか2010

    • Author(s)
      稲垣宏
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 唾液腺原発粘表皮癌におけるCRTC3-MAML2キメラ遺伝子の臨床病理学的意義2010

    • Author(s)
      中山崇久, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 粘表皮癌におけるCRTCI-MAMI2、CRCT3-MAML2キメラ遺伝子の臨床病理学的意義2010

    • Author(s)
      奥村嘉英, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 非ホルマリン系組織固定液の有用性に関する検討2010

    • Author(s)
      榊原健夫, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Oncocytomaと鑑別が困難であった腎臓のpapillary renal cell carcinomaの一例2010

    • Author(s)
      藤吉行雄, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 膿胸関連肉腫の1症例2010

    • Author(s)
      服部日出雄, 稲垣宏, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 肺MALT リンパ腫における遺伝子異常とIgH 遺伝子体細胞変異2010

    • Author(s)
      夏洪晶, 稲垣宏, 他
    • Organizer
      第50回日本リンパ網内系学会総会
    • Place of Presentation
      新潟(新潟コンベンションセンター)
    • Related Report
      2010 Annual Research Report
  • [Presentation] A CDC-enhancing anti-CD20 mAb mediating potent antitumor activity in the humanized NOG mouse model2010

    • Author(s)
      Ito A, Inagaki H, et al.
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Related Report
      2010 Annual Research Report
  • [Presentation] サルコイドーシスに合併した腹部大動脈破裂の1部検例2009

    • Author(s)
      小湊知、稲垣宏、他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2009-05-01 – 2009-05-03
    • Related Report
      Products Report
  • [Presentation] 腎静脈発生と考えられた腎平滑筋肉腫の1例2009

    • Author(s)
      中山崇久、稲垣宏、他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2009-05-01 – 2009-05-03
    • Related Report
      Products Report
  • [Presentation] 小児こう胞性疾患の免疫染色的検討2009

    • Author(s)
      清水重喜、稲垣宏、他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2009-05-01 – 2009-05-03
    • Related Report
      Products Report
  • [Presentation] 造血系腫瘍の病理学的概要2009

    • Author(s)
      稲垣宏
    • Organizer
      第3回伴侶動物の臨床医学研究会(招待講演)
    • Place of Presentation
      岡崎コンファレンスセンター(愛知)
    • Related Report
      2011 Final Research Report
  • [Presentation] 悪性リンパ腫:病理診断と治療2009

    • Author(s)
      稲垣宏
    • Organizer
      第48回中部医学検査学会(招待講演)
    • Place of Presentation
      三島市民文化会館(静岡)
    • Related Report
      2011 Final Research Report
  • [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立2009

    • Author(s)
      伊藤旭、稲垣宏、他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Related Report
      2011 Final Research Report
  • [Presentation] EBER陽性のALK陰性anaplastic large cell lymphoma(ALCL)の2例2009

    • Author(s)
      稲垣淳、稲垣宏、他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Related Report
      2011 Final Research Report
  • [Presentation] B-LBLモデルマウスの樹立及び病態解析2009

    • Author(s)
      森芙美子、稲垣宏、他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Related Report
      2011 Final Research Report
  • [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立2009

    • Author(s)
      伊藤旭、稲垣宏、他
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Related Report
      2011 Final Research Report
  • [Presentation] 胸腺MALTリンパ腫における遺伝子過剰メチル化とFas遺伝子異常の解析2009

    • Author(s)
      滝野寿、稲垣宏、他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会議場(京都)
    • Related Report
      2011 Final Research Report
  • [Presentation] サルコイドーシスに合併した腹部大動脈破裂の1剖検例2009

    • Author(s)
      小湊知, 稲垣宏, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] 胸腺MALTリンパ腫における遺伝子過剰メチル化とFas遺伝子異常の解析2009

    • Author(s)
      滝野寿, 稲垣宏, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] 腎静脈発生と考えられた腎平滑筋肉腫の1例2009

    • Author(s)
      中山崇久, 稲垣宏, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立2009

    • Author(s)
      伊藤旭, 稲垣宏, 他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] EBER陽性のALK陰性 anaplastic large cell lymphoma(ALCL)の2例2009

    • Author(s)
      稲垣淳, 稲垣宏, 他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] B-LBLモデルマウスの樹立及び病態解析2009

    • Author(s)
      森芙美子, 稲垣宏, 他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      京都
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト免疫担当細胞移入NOD/Shi-scid, IL2Rgamma null(NOG)マウスを用いた抗体療法評価システムの確立2009

    • Author(s)
      伊藤旭, 稲垣宏, 他
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] 悪性リンパ腫:病理診断と治療2009

    • Author(s)
      稲垣宏
    • Organizer
      第48回中部医学検査学会
    • Place of Presentation
      三島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 造血系腫瘍の病理学的概要2009

    • Author(s)
      稲垣宏
    • Organizer
      第三回伴侶動物の臨床医学研究会
    • Place of Presentation
      岡崎
    • Related Report
      2009 Annual Research Report
  • [Book] 癌診療指針のための病理診断プラクティス:食道癌・胃癌2012

    • Author(s)
      稲垣宏, 楠本茂, 片岡洋望
    • Total Pages
      307
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 癌診療指針のための病理診断プラクティス:リンパ球増殖疾患2010

    • Author(s)
      稲垣宏, 楠本茂
    • Total Pages
      335
    • Publisher
      中山書店
    • Related Report
      2011 Final Research Report
  • [Book] WHO血液腫瘍分類WHO分類2008をうまく活用するために2010

    • Author(s)
      佐藤文彦、稲垣宏
    • Total Pages
      587
    • Publisher
      医薬ジャーナル社
    • Related Report
      2011 Final Research Report
  • [Book] 癌診療指針のための病理診断プラクティス2010

    • Author(s)
      稲垣宏, 楠本茂
    • Total Pages
      335
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Book] WHO血液腫瘍分類:WHO分類2008をうまく活用するために2010

    • Author(s)
      佐藤文彦, 稲垣宏
    • Total Pages
      587
    • Publisher
      医薬ジャーナル社
    • Related Report
      2010 Annual Research Report
  • [Book] WHO血液腫瘍分類 WHO分類2008をうまく活用するために2010

    • Author(s)
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    • Total Pages
      587
    • Publisher
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    • Related Report
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  • [Remarks]

    • URL

      http://www.med.nagoya-cu.ac.jp/patho2.dir/4pep.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://www.med.nagoya-cu.ac.jp/patho2.dir/4pep.html

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.nagoya-cu.ac.jp/patho2.dir/index.htm

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.nagoya-cu.ac.jp/patho2.dir/index.htm

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-09-09  

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