Study on Function of Eukaryotic Protein Kinase and Phosphatase in Firmicutes
| Project/Area Number |
21590482
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | Kagawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MIYATA Shigeru 香川大学, 医学部, 講師 (90314913)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ガス壊疽菌 / シグナル伝達 / リン酸化 / 形態形成 / プロテインキナーゼ / プロテインホスファターゼ / Clostridium perfringens / 多様性 / In-Frame遺伝子欠損 / プロテインボスファターゼ / Yeast-Two Hybrid |
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| Research Abstract |
Protein Ser/ Thr Kinase(K)-Phosphatase(P) plays essential roles in regulation of cellular functions in both prokaryotes and eukaryotes. Although Clostridia have also the K-P systems, they have not been investigated. In this study, we revealed function of the K-P system in C. perfringens by analyzing in-frame deletion mutants of the system and the target protein(S) for K identified. Our results indicate that the K-P system regulates morphology of Clostridia via phosphorylation of S.
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Report
(4 results)
Research Products
(47 results)
