| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Research Abstract |
Virulent proteins play important roles in the pathogenesis of Streptococcus pyogenes that causes streptococcal toxic shock syndrome. Nutritious conditions, especially carbohydrates are considered to be related with the productions of virulent proteins. For utilizing carbohydrates, bacteria need to take through transporters located in the membrane. In this project, we have studied the roles of transcriptional terminators and two-component regulatory proteins which may regulate the production of transporters. We have showed these regulatory factors were involved for specific carbohydrate utilizations and toxic protein productions.
|
