Role of CM2 in the influenza C virus replication cycle
| Project/Area Number |
21590505
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Virology
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HONGO Seiji 山形大学, 医学部, 教授 (90229245)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | C型インフルエンザウイルス / 粒子形成 / uncoating / packaging / CM2蛋白質 / 増殖機構 |
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| Research Abstract |
The aim of the present study is to elucidate the role of CM2 in the influenza C virus replication cycle. We generated wild-type and CM2-deficient virus-like particles and examined the VLP-producing cells, VLPs and VLP-infected cells. The results showed that CM2 is involved in uncoating and packaging processes.
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Report
(4 results)
Research Products
(72 results)
