Development of automated device for the assessment of platelet aggregation using Platelet-rich plasma and whole blood samples

• Project/Area Number: 21590618
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Laboratory medicine
• Research Institution: University of Yamanashi
• Principal Investigator: SATOH Kaneo 山梨大学, 医学部, 助手 (20242662)
• Co-Investigator(Kenkyū-buntansha): OZAKI Yukio 山梨大学, 大学院・医学工学総合研究部, 教授 (30134539)
• Project Period (FY): 2009 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 臨床検査医学 / 検査血液学 / 血小板凝集能検査 / 自動化法 / マイクロプレート / 血小板凝集能測定装置 / 自動化

Research Abstract

Platelet aggregometer based on the optical density method can be measured up to 4 tests, which is induced by ADP or arachidonic acid. The new automated device can be measured up to 24 tests induced by the agonists. The new device have results under lower efforts, lower costs and small sample volume than the optical density method.

Research Products

• [Journal Article] 血小板機能の新しい展開:血栓以外の役割 (2012)
  • Author(s): 尾崎由基男
  • Journal Title: 臨床病理 Volume: 60 Pages: 52-59
  • NAID: 10030463065
  • Peer Reviewed
• [Journal Article] Causes of thrombocytopenia in chronic hepatitis C viral infection (2012)
  • Author(s): Osada M, Kaneko M, Sakamoto M, Endoh M, Takigawa K, Suzuki-Inoue K, Inoue O, Satoh K, Enomoto N, Yatomi Y, Ozaki Y
  • Journal Title: Clin Appl Thromb Hemost Volume: 18 Pages: 272-80
  • Peer Reviewed
• [Journal Article] Novel synthetic collagen fibers, poly(PHG), stimulate platelet aggregation through glycoprotein VI (2009)
  • Author(s): Inoue O, Suzuki-Inoue K, Shinoda D, Umeda Y, Uchino M, Takasaki S, Ozaki Y.
  • Journal Title: FEBS Lett Volume: 583 Pages: 81-7
  • Peer Reviewed
• [Presentation] 血小板機能の新しい展開血栓以外の役割 (2011)
  • Author(s): 尾崎由基男
  • Organizer: 日本臨床検査医学会
  • Place of Presentation: 岡山
  • Year and Date: 2011-11-27
• [Presentation] 血小板機能の新しい展開血栓以外の役割 (2011)
  • Author(s): 尾崎由基男
  • Organizer: 日本臨床検査医学会
  • Place of Presentation: 岡山コンベンションセンター(岡山県)(招待講演)
  • Year and Date: 2011-11-17
• [Presentation] 血栓止血領域の診断、治療の最先端を探る血小板機能検査の現状と課題 (2011)
  • Author(s): 尾崎由基男
  • Organizer: 日本医学検査学会
  • Place of Presentation: 東京
  • Year and Date: 2011-06-04
• [Presentation] 血栓止血領域の診断、治療の最先端を探る血小板機能検査の現状と課題 (2011)
  • Author(s): 尾崎由基男
  • Organizer: 日本医学検査学会
  • Place of Presentation: 東京国際フォーラム(東京都)(招待講演)
  • Year and Date: 2011-06-04
• [Remarks]
  • URL: http://www.med.yamanashi.ac.jp/clinical/clin0lab/
• [Remarks]
  • URL: http://www.med.yamanashi.ac.jp/clinical/clin01ab/