Remodeling of lymph vessels in the fibrotic lesion of bronchioloalveolar cell carcinoma
Project/Area Number |
21590619
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Laboratory medicine
|
Research Institution | Shinshu University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
UEHARA Takeshi 信州大学, 医学部, 講師 (80402121)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 肺癌 / 肺腺癌 / リンパ管 / リンパ管侵襲 / 腺癌 / 肺 / 気管支肺胞上皮癌 / 線維化 |
Research Abstract |
The aim of this study is to clear three-dimensional morphological changes of lymphatic vessels in a progression of BAC. In the normal alveolar region, they straightly elongated without bifurcation and most of them were compressed. In the central portion of the fibrotic lesion, the density of lymph vessels was higher and the lumens were wider. The lymph vessels morphologically changed to a tank. As the BAC advances forming central fibrosis, the volume ratio of the lymph vessels to the whole one of the cancer will become larger, and probability of carcinoma cell invasion to the lymph vessels will increase.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Comparative study of three different catheters for CT imaging-bronchoscopy-guided radiofrequency ablation as a potential and novelinterventional therapy for lung cancer2011
Author(s)
Tanabe T, Koizumi T, Tsushima K, Ito M, Kanda S, Kobayashi T, Yasuo M, Yamazaki Y, Kubo K, Honda T, Kondo R, Yoshida K
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Journal Title
Chest
Volume: 137
Pages: 890-897
URL
Related Report
Peer Reviewed
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[Journal Article] Malignant hepatic epithelioid hemangioendothelioma withrapid progression and fatal outcome2010
Author(s)
Komatsu Y, Koizumi T, Yasuo M, Urushihata K, Yamamoto H, Hanaoka M, Kubo K, Kawakami S, Honda T, Fujimoto K, Hachiya T
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Journal Title
Intern Med
Pages: 1149-1153
NAID
URL
Related Report
Peer Reviewed
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[Journal Article] Comparative study of three different catheters for CT imaging-bronchoscopy-guided radiofrequency ablation as a potential and novel interventional therapy for lung cancer2010
Author(s)
Tanabe T, Koizumi T, Tsushima K, Ito M, Kanda S, Kobayashi T,Yasuo M, Yamazaki Y, Kubo K, Honda T, Kondo R, Yoshida K.
-
Journal Title
Chest
Volume: 137
Pages: 890-897
Related Report
Peer Reviewed
-
[Journal Article] Malignant hepatic epithelioid hemangioendothelioma with rapid progression and fatal outcome.2010
Author(s)
Komatsu Y, Koizumi T, Yasuo M, Urushihata K, Yamamoto H, Hanaoka M, Kubo K, Kawakami S, Honda T, Fujimoto K, Hachiya T.
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Journal Title
Intern Med
Volume: 49
Pages: 1149-1153
NAID
Related Report
Peer Reviewed
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